Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(274.923 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.873 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Cinnamyl Alcohol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Cinnamyl alcohol is used as a fragrance ingredient and is a known a cause of allergic dermatitis in humans. Cinnamyl alcohol is also part of a group of cinnamic acid derivatives (for example: 4-Methoxycinnamic acid -M262150) that might be useful for the treatment of diabetes and obesity.<br>References Adisakwattana, S., et al.: J. Emzym. Inhib., 28, 1067, (2013); Basketter, D.: Acta-Derm.-Venereol., 72, 264 (1992); Letizia, C. S., et al.: Food Chem. Toxicol., 43, 837 (2005);<br></p>Fórmula:C9H10OCor e Forma:Light YellowPeso molecular:134.18Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Fórmula:C12H13NCor e Forma:OrangePeso molecular:171.241,3-Diphenylurea
CAS:<p>Applications 1,3-Diphenylurea (cas# 102-07-8) is a useful research chemical.<br></p>Fórmula:C13H12N2OCor e Forma:NeatPeso molecular:212.252-Bromoanthracene
CAS:Produto Controlado<p>Applications 2-Bromoanthracene<br></p>Fórmula:C14H9BrCor e Forma:NeatPeso molecular:902.9572-(Dimethylamino)guanosine
CAS:Produto Controlado<p>Applications 2-(Dimethylamino)guanosine (cas# 2140-67-2) is a compound useful in organic synthesis.<br></p>Fórmula:C12H17N5O5Cor e Forma:NeatPeso molecular:311.29Amlodipine Dimethyl Ester
CAS:<p>Impurity Amlodipine EP Impurity F / Amlodipine USP Related Compound F<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity F<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Fórmula:C19H23ClN2O5Cor e Forma:Light Yellow To YellowPeso molecular:394.85Des-4-fluorobenzyl Mosapride
CAS:Produto Controlado<p>Applications The major metabolite of Mosapride (M731000).<br>References Somogyi, A., et al.: Clin. Pharmacokinet., 8, 463 (1983), Cashman, J., et al.: Drug Metab. Dispos., 21, 587 (1993), Berkman, C., et al.: Biochem. Pharmacol., 50, 565(1995), Blake, B., et al.: Xenobiotica, 25, 377 (1995),<br></p>Fórmula:C14H20ClN3O3Cor e Forma:NeatPeso molecular:313.783,3'-di-tert-Butyl-5,5'-dimethoxybiphenyl-2,2'-diol
CAS:Produto Controlado<p>Applications 3,3'-di-tert-butyl-5,5'-dimethoxybiphenyl-2,2'-diol (cas# 14078-41-2) is a useful research chemical.<br></p>Fórmula:C22H30O4Cor e Forma:Light OrangePeso molecular:358.471Isometheptene Maleate
CAS:<p>Applications Isometheptene Maleate belongs to a group of sympathomimetic amine and shows very little antihypertensive activity. Isometheptene Maleate is used as an antispasmodic drug.<br>References Vidrio, H. et al.: J. Pharmacol. Exp. Therap., 187, 308 (1973); Taylor, W.G. et al.: Drug Metab. Disp., 5, 564 (1977);<br></p>Fórmula:C9H19N·C4H4O4Cor e Forma:White To Off-WhitePeso molecular:257.33Tetrachloroauric Acid
CAS:Produto Controlado<p>Applications Tetrachloroauric Acid, is used for the recovery, concentrating, purification, and analytical determinations of gold. It is the precursor used in the purification of gold by electrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mironov, I. V., et al.: Russian J. Inorg. Chem., 57, 610 (2012); Feather, A., et al.: J. Southern Africa Inst. mining Metal., 169 (1997);<br></p>Fórmula:AuCl3·ClHCor e Forma:NeatPeso molecular:339.79Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Cor e Forma:NeatPeso molecular:330.38Ambrisentan
CAS:Produto Controlado<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H22N2O4Cor e Forma:Off-WhitePeso molecular:378.425α-Pregnane-3β,20(S)-diol
CAS:Produto Controlado<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Cor e Forma:NeatPeso molecular:320.51Dehydro Nicardipine Hydrochloride
CAS:<p>Impurity Nicardipine USP Related Compound B<br>Applications A pyridine metabolite M-5 of Nicardipine. Nicardipine USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Triggle, A., et al.: J. Med. Chem., 23, 1442 (1980), Freedman, D., et al.: Drugs, 34, 578 (1987), Guengerich, F., et al.: Xenobiotica, 25, 689 (1995), Schleifer, K., et al.: Pharmazie, 54, 804 (1999),<br></p>Fórmula:C26H27N3O6·ClHCor e Forma:NeatPeso molecular:513.979-Methyl Adenine-d3
CAS:Produto Controlado<p>Applications Labelled receptor adenine derivative binding membrane brain animal cell line.<br>References Camaioni, E., et al.: Bioorg. Med. Chem., 6, 523 (1998), Kelly, M., et al.: Br. J. Pharmacol., 125, 979 (1998), Redzic, Z., et al.: Brain Res., 888, 66 (2001), Levy, D., et al.: J. Med. Chem., 46, 2177 (2003),<br></p>Fórmula:C62H3H4N5Cor e Forma:NeatPeso molecular:152.1719-Norandrosterone
CAS:Produto Controlado<p>Applications 19-Norandrosterone is the oxidized byproduct of Nandrolone (N315000), an anabolic steroid that is present naturally in the human body.<br>References Jiang, J.Q., et al.: J. Food. Sci., 77, 63 (2012); Delgadillo, M.A., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 897 (2012);<br></p>Fórmula:C18H28O2Cor e Forma:NeatPeso molecular:276.41Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C98H137N23O34•xC2HF3O2Cor e Forma:NeatPeso molecular:2181.271α-(Chloromethyl) Chlormadinone Acetate
CAS:Produto Controlado<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Fórmula:C24H30Cl2O4Cor e Forma:NeatPeso molecular:453.40Muraglitazar
CAS:Produto Controlado<p>Applications It is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist.<br>References Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 6, 427 (2005), Devasthale, P.V., et al.: J. Med. Chem., 48, 2248 (2005), Kendall, D.M., et al.: Diabetes care, 29, 1016 (2006),<br></p>Fórmula:C29H28N2O7Cor e Forma:NeatPeso molecular:516.54γ-Butyrobetaine-d9
CAS:Produto Controlado<p>Applications γ-Butyrobetaine-d9 is the labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002)<br></p>Fórmula:C72H9H7NO2Cor e Forma:NeatPeso molecular:155.26Diacetyl Bis(2,4-dinitrophenylhydrazone)
CAS:Produto Controlado<p>Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C16H14N8O8Cor e Forma:NeatPeso molecular:446.334-Hydroxy Estrone 1-N7-Guanine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Cor e Forma:NeatPeso molecular:435.48CRL-40,941
CAS:Produto Controlado<p>Applications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.<br>References Lafon, L.: US4489095 (A) (1984)<br></p>Fórmula:C15H13F2NO3SCor e Forma:WhitePeso molecular:325.336-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt
CAS:<p>Applications 6-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt is used the in the synthesis of azo dyes and pigments.<br>References Gao, Pu. et al., Dyes Pigm. 179, 108376(2020);<br></p>Fórmula:C10H7O4S·KCor e Forma:NeatPeso molecular:262.3235Bis (2-Ethylhexyl) 4,4’-(6-(4-(ethoxycarbonyl)phenylamino)-1,3,5-triazine-2,4-diyl)bis(azanediyl)dibenzoate
Fórmula:C42H54N6O6Cor e Forma:NeatPeso molecular:738.91Isopilocarpic Acid Sodium Salt
CAS:Produto Controlado<p>Impurity Pilocarpine Hydrochloride EP Impurity C<br>Stability Hygroscopic<br>Applications Isopilocarpic Acid is a degradation product of Pilocarpine (P441500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szepesi, G. et al.: Pharmazie, 38, 94 (1983); Bundgaard, H. et al.: Int. J. Pharmac., 10, 281 (1982);<br></p>Fórmula:C11H17N2O3·NaCor e Forma:WhitePeso molecular:248.25α-Naphthyl Glycidyl Ether, 90%
CAS:Produto Controlado<p>Applications Used in the preparation of Naftopidil (N213500) and propranolol (P831800).<br>References Erhard, P., et al.: J. Med. Chem., 25, 1402 (1982), Campbell, L., et al.: BioMed. Chem. Lett., 4, 2627 (1994),<br></p>Fórmula:C13H12O2Pureza:90%Cor e Forma:NeatPeso molecular:200.23(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
CAS:Produto Controlado<p>Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>Fórmula:C17H17NO4Cor e Forma:Off White PowderPeso molecular:299.32Tetramethylol Acetylenediurea
CAS:Produto Controlado<p>Applications Tetramethylol Acetylenediurea is a useful additive for forming etching patterns in semiconductor manufacturing.<br>References Lee, S. J., et al.: PCT Int. Appl. (2020), WO 2020184904 A1<br></p>Fórmula:C8H14N4O6Cor e Forma:NeatPeso molecular:262.22Camphorquinone-10-sulfonic Acid Hydrate
CAS:Produto Controlado<p>Applications A crystalline water-soluble reagent that is useful for specific, reversible modification of the guanidino groups of arginine residues. Suitable for use with small arginine-containing molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallace, C.J.A., et al.: Biochem. J., 215, 651 (1983), Dailey, H.A., et al.: J. Biol. Chem., 261, 7902 (1986),<br></p>Fórmula:C10H14O5S·H2OCor e Forma:NeatPeso molecular:264.304-Benzyloxyacetophenone
CAS:Produto Controlado<p>Applications 4-Benzyloxyacetophenone is used in preparation of inhibitors of various proteins such as hepatitis C virus polymerase, glucosylceramide synthase and protein tyrosine phosphatase 1B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deng, Y., et al.: Bioorg. Med. Chem. Lett., 19, 5363 (2009); Lee, L., et al.: J. Biol. Chem., 274, 14662 (2009); Liu, Z., et al.: Bioorg. Med. Chem. Lett., 21, 3755 (2011)<br></p>Fórmula:C15H14O2Cor e Forma:NeatPeso molecular:226.274-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic Acid
CAS:Produto Controlado<p>Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.<br></p>Fórmula:C12H8F3NO2SCor e Forma:NeatPeso molecular:287.26Allo-3α-tetrahydro Cortisol
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Cortisol (H714615).<br>References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),<br></p>Fórmula:C21H34O5Cor e Forma:Off White SolidPeso molecular:366.491,5-Dibromoanthracene
CAS:Produto Controlado<p>Applications 1,5-dibromoanthracene (cas# 3278-82-8) is a useful research chemical.<br></p>Fórmula:C14H8Br2Cor e Forma:NeatPeso molecular:336.02Chenodeoxycholic acid-3-β-D-glucuronide
CAS:Produto ControladoFórmula:C30H48O10Cor e Forma:White To Off-WhitePeso molecular:568.7N-Des((tetrahydrofuran-2-yl)methanone)) Terazosin Dihydrochloride
CAS:Produto Controlado<p>Applications N-Des((tetrahydrofuran-2-yl)methanone)) Terazosin Dihydrochloride is a related compound to Terazosin (T105000), a α-1-adrenergic blocker related to Prazosin (P702325).<br>References Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984), Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984), Lepor, H., et al.: J. Urol., 148, 1467 (1992),<br></p>Fórmula:C14H19N5O2HClCor e Forma:NeatPeso molecular:362.25Indole-3-butyric Acid
CAS:<p>Applications Used to stimulate root formation of plant clippings. Suitable for plant cell culture tested.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Handa, A., et al.: Plant Physiol., 69, 514 (1982), Polanco, C., et al.: Plant Sci., 162, 817 (2002), Rzepka-Plevnes, D., et al.: J. Food Agric. Environ., 5, 194 (2007),<br></p>Fórmula:C12H13NO2Cor e Forma:BeigePeso molecular:203.24Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Fórmula:C20H24N2O3SCor e Forma:White To BrownPeso molecular:372.485-Iodovanillic Acid
CAS:Produto Controlado<p>Applications 5-Iodovanillic acid (cas# 98554-57-5) is a useful research chemical.<br></p>Fórmula:C8H7IO4Cor e Forma:Off-WhitePeso molecular:294.04Benoxaprofen
CAS:Produto Controlado<p>Applications A non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003), Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),<br></p>Fórmula:C16H12ClNO3Cor e Forma:NeatPeso molecular:301.726-Hydroxy-2-naphthaleneacetic Acid
CAS:<p>Applications A metabolite of Nabumetone.<br>References Nobilis, M., et al.: J., Pharm., Biomed., Anal., 32, 641 (2003),<br></p>Fórmula:C12H10O3Cor e Forma:NeatPeso molecular:202.21Androstenediol 3-Acetate
CAS:Produto Controlado<p>Applications Androstenediol 3-Acetate is an intermediate in the synthesis of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Stastna, E., et al.: Steroids., 75, 721 (2010);<br></p>Fórmula:C21H32O3Cor e Forma:NeatPeso molecular:332.48trans-α-Asarone
CAS:Produto ControladoFórmula:C12H16O3Cor e Forma:White To Off-WhitePeso molecular:208.25Bromfenac Sodium Sesquihydrate
CAS:Produto Controlado<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C15H11BrNO3·2Na·3H2OCor e Forma:Light YellowPeso molecular:766.34Acetyl-1,2-13C2 Coenzyme A Sodium Salt (~2% Unlabelled)
CAS:Produto Controlado<p>Applications Acetyl-1,2-13C2 Coenzyme A Sodium Salt is a useful synthetic intermediate.<br></p>Fórmula:C2113C2H38N7O17P3S•x(Na)Cor e Forma:NeatPeso molecular:811.5622992,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5
CAS:Produto Controlado<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>Fórmula:C13D5H5O4Cor e Forma:NeatPeso molecular:235.247Acetyldiethylstilbestrol 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester
CAS:Produto Controlado<p>Applications Intermediate for the preparation of Diethylstilbestrol β-D-Glucuronide.<br></p>Fórmula:C33H38O12Cor e Forma:Light YellowPeso molecular:626.65N-Isopropyl Noratropine
CAS:Produto Controlado<p>Impurity Ipratropium EP Impurity E<br>Applications N-Isopropyl Noratropine is a Noratropine derivative, an intermediate in the production of Ipratropium.<br>References Simms, P., et al.: J. Pharm. Biomed. Anal., 17, 841 (1998),<br></p>Fórmula:C19H27NO3Cor e Forma:NeatPeso molecular:317.42(-)-Citronellal
CAS:Produto Controlado<p>Applications (-)-Citronellal is the s-isomer of (R)-Citronellal (C525025), a natural insect repellant. (-)-Citronellal (a monoterpene) was found to activate human olfactory receptor OR1A2 at the mRNA and protein levels resulting in reduced cell proliferation and reduced hepatocellular carcinoma progression.<br>References Massberg, D., et al.: Arch. Biochem. Biophys., 566, 100 (2015);<br></p>Fórmula:C10H18OCor e Forma:NeatPeso molecular:154.25(S)-Duloxetine Phthalamide
CAS:Produto Controlado<p>Impurity Duloxetine Phthalamide Impurity<br>Applications (S)-Duloxetine Phthalamide is an impurity of (S)-Duloxetine present with enteric polymer hydroxypropylmethylcellulose phthalate (HPMCP) in dosage formulations.<br>References Jansen, P.J., et al.: J. Pharmaceut. Sci., 87, 81 (1998),<br></p>Fórmula:C26H23NO4SCor e Forma:White To Off-WhitePeso molecular:445.53Tenivastatin Calcium Hydrate
CAS:Produto Controlado<p>Applications Tenivastatin Calcium is derived from Simvastatin (S485000), which is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.<br>References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986)<br></p>Fórmula:C25H39O6Ca·xH2OCor e Forma:NeatPeso molecular:929.242-Naphthylacetonitrile
CAS:Produto Controlado<p>Applications 2-Naphthylacetonitrile (cas# 7498-57-9) is a useful research chemical.<br></p>Fórmula:C12H9NCor e Forma:NeatPeso molecular:167.21N-Desmethyl Rosuvastatin Disodium Salt Monohydrate
CAS:Produto Controlado<p>Applications Inhibits the enzyme HMG-CoA reductase in vitro.<br>References Endo, A., et al.: J. Antibiot., 32, 852 (1979), Alberts, A.W., et al.: Drug Invest., 2 (Suppl. 2), 9 (1990), Kuroda, M., et al.: Biochim. Biophys. Acta, 486, 70 (1977),<br></p>Fórmula:C21H24FN3Na2O6S•H2OCor e Forma:NeatPeso molecular:511.481802Gibberellin A34 (>90%)
CAS:Fórmula:C19H24O6Pureza:>90%Cor e Forma:Light Yellow SolidPeso molecular:348.39Droxicam
CAS:Produto Controlado<p>Applications Droxicam is a non-steroidal anti-inflammatory drug.<br>References Lapeyre-Mestre, M., et. al.: Fundam. Clin. Pharm., 20, 391 (2006)<br></p>Fórmula:C16H11N3O5SCor e Forma:Off-White To Light YellowPeso molecular:357.344-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS:Produto Controlado<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Fórmula:C23H26O3Cor e Forma:NeatPeso molecular:350.45N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Cor e Forma:NeatPeso molecular:415.573,5,6-Trichlorosalicylic Acid
CAS:Produto Controlado<p>Applications 3,5,6-TRICHLOROSALICYLIC ACID (cas# 40932-60-3) is a useful research chemical.<br></p>Fórmula:C7H3Cl3O3Cor e Forma:NeatPeso molecular:241.46(+)-(S)-Dihydrokavain
CAS:Produto Controlado<p>Applications (+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.<br>References Warburton, E., et al.: Eur. J. Mass Spectrom., 12, 223(2006); Wang, J., et al.: J. Food Sci. Technol., 52, 1164 (2015)<br></p>Fórmula:C14H16O3Cor e Forma:NeatPeso molecular:232.283'-Chloropropiophenone
CAS:Produto Controlado<p>Impurity Bupropion Des-t-Butylamino Impurity<br>Applications 3'-Chloropropiophenone is a reagent used in the vinylation, alkylation and dienylation of ketones. It is also used in the preparation of thizaine derivatives that show antibacterial activity.<br>References Li, H. et al.: J. Am. Chem. Soc., 127, 8355 (2005); Deepika, G. et al.: J. Pharm. Res., 5, 1105 (2012);<br></p>Fórmula:C9H9ClOCor e Forma:NeatPeso molecular:168.6202Betaine-d3 Hydrochloride
CAS:Produto Controlado<p>Applications Betaine-d3 Hydrochloride is a useful gastric acidifier.<br>References Wilcken, D.E., et al.: N. Engl. J. Med., 309, 448 (1983),<br></p>Fórmula:C52H3H9NO2·ClCor e Forma:White To Off-WhitePeso molecular:156.631,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine
CAS:Produto Controlado<p>Applications 1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine is used as a stabilizer for Irganox MD 1024 on thermo-oxidative stability of PP/PP-g-MA/OMMT nanocomposites.<br>References Fitaroni, L, B.; et al.: Polym. Test., 53, 165 (2016).<br></p>Fórmula:C34H52N2O4Cor e Forma:White To Off-WhitePeso molecular:552.7877Formic Acid, 97+%
CAS:Produto Controlado<p>Stability Volatile<br>Applications Formic Acid is used as a potential energy source in the preparation of fuel cells. Also used in chemical synthesis of various anti-inflammatory and anti-microbial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yu, X. et al.: J. Power Source., 182, 124 (2008); Bekhit, A. et al.: Bioorg. Med. Chem., 12, 1935 (2004);<br></p>Fórmula:CH2O2Pureza:97%Cor e Forma:ColourlessPeso molecular:46.033-Sulfoglycolithocholic Acid Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.<br>References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)<br></p>Fórmula:C26H41NO7S·2NaCor e Forma:NeatPeso molecular:557.651,5-Dinitronaphthalene
CAS:Produto Controlado<p>Applications 1,5-DINITRONAPHTHALENE (cas# 605-71-0) is a useful research chemical.<br></p>Fórmula:C10H6N2O4Cor e Forma:NeatPeso molecular:218.17Vanillylmethanol
CAS:Produto Controlado<p>Applications An odorant found in strawberries, grapes and olive oil. Vanillylmethanol has high scavenging activities and inhibits homocysteine-induced endothelial cell adhesion.<br>References Ubeda, C. et al.: J. Agr. Food. Chem., 60, 6095 (2012); Barata, A. et al.: J. Agr. Food Chem., 59, 2543 (2011); Manna, C. et al.: J. Agr. Food Chem., 57, 3478 (2009)<br></p>Fórmula:C9H12O3Cor e Forma:NeatPeso molecular:168.192,2'-Thiodiacetic Acid
CAS:Produto Controlado<p>Applications 2,2'-Thiodiacetic Acid is a highly flexible ligand used in the synthesis of a series of metal complexes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hou, X., et al.: Chin. J. Struct. Chem., 32, 1339 (2013); Wu, X.X., et al.: Synth. React. Inorg. Me., 44, 486 (2014); Ma, C., et al.: J. Inorg. Organomet. P., 22, 1206 (2012)<br></p>Fórmula:C4H6O4SCor e Forma:NeatPeso molecular:150.15Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt is a metabolite of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993),<br></p>Fórmula:C24H23FNNaO3Cor e Forma:NeatPeso molecular:415.43Phenylglyoxylic Acid-13C8
CAS:<p>Applications Phenylglyoxylic Acid-13C8 is an intermediate used in the synthesis of Mandelic Acid-13C8 (M162523), which is the C13 labelled Mandelic Acid which is used as an antiseptic (urinary). It is also used as a short-term exposure biomarker in urine from styrene exposed workers.<br>References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007); Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009); Fustinoni, S., et al.: Toxicol. Lett., 192, 40 (2010)<br></p>Fórmula:C8H6O3Cor e Forma:NeatPeso molecular:158.07Beclomethasone 21-Propionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity A<br>Applications Beclomethasone 21-Propionate (Beclomethasone Dipropionate EP Impurity A) is a metabolite of Beclomethasone Dipropionate (BDP).<br>References Foe, K., et al.: Biopharm. Drug Disposition, 19, 1 (1998), Harrison, L., et al.: Eur. J. Clin. Pharmacol., 58, 197 (2002),<br></p>Fórmula:C25H33ClO6Cor e Forma:WhitePeso molecular:464.98Carvedilol Bis-carbazole
CAS:Produto Controlado<p>Impurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B<br>Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).<br></p>Fórmula:C39H39N3O6Cor e Forma:Off-White To Light BeigePeso molecular:645.742-Naphthylacetic Acid
CAS:Produto Controlado<p>Applications 2-Naphthylacetic acid can be used to synthesize hydrolase inhibitors. It can also be utilized for developing γ-dipeptide derivatives that can bind human somatostatin receptors.<br>References Tarzia, G., et al.: J. Med. Chem. 46, 2352 (2003); Seebach, D., et al.: Angew. Chem. Int. Ed. 42, 776 (2003)<br></p>Fórmula:C12H10O2Cor e Forma:NeatPeso molecular:186.21Limonin
CAS:<p>Applications Limonin is a limonoid extracted from various citrus plants. Bioactivity of Limonin have been revolved around its anti-HIV properties.<br>References Battinelli, L., et al.: Planta. Med., 69, 910 (2003); Kim, J., et al.: Food. Function., 4, 258 (2013); Chaudhary, P., et al.: Food. Chem., 135, 1667 (2012);<br></p>Fórmula:C26H30O8Cor e Forma:NeatPeso molecular:470.51Potassium p-Nitrophenyl Sulphate
CAS:<p>Applications Potassium p-Nitrophenyl Sulphate (cas# 6217-68-1) is a compound useful in organic synthesis.<br></p>Fórmula:C6H4NO6S·KCor e Forma:NeatPeso molecular:257.262-Methylnaphthalene-D10
CAS:Produto Controlado<p>Applications 2-Methylnaphthalene-D10 is a labelled analogue of 2-Methylnaphthalene (M323130). 2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been used as an indicator of smoke exposure in food and packaging materials.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Johnston, J.J., et. al.: J. Agr. Food Chem., 42, 1954 (1994)<br></p>Fórmula:C112H10Cor e Forma:NeatPeso molecular:152.263,3'-Dichlorobenzidine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,3'-Dichlorobenzidine Dihydrochloride, is structurally similar to Benzidine (B121000), and thus is considered a carcinogen. It can be used in the production of azo dyes. Dyes and metabolites, Environmental Testing<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Min, Zh., et al.: Chem. Res. Toxic., 26, 741 (2013); Rainer, F., et al.: Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis, 691, 27 (2010);<br></p>Fórmula:C12H10Cl2N2·2ClHCor e Forma:NeatPeso molecular:326.051-Phenyl-1,2,3,4-tetrahydronaphthalene
CAS:<p>Applications 1-phenyl-1,2,3,4-tetrahydronaphthalene (cas# 3018-20-0) is a useful research chemical.<br></p>Fórmula:C16H16Cor e Forma:ColourlessPeso molecular:208.298Betamethasone 21-Propionate
CAS:Produto Controlado<p>Impurity Clobetasol Propionate EP Impurity K / Betamethasone Dipropionate EP Impurity C<br>Applications Betamethasone 21-Propionate (Clobetasol Propionate EP Impurity K) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Cor e Forma:Off-WhitePeso molecular:448.52Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Produto Controlado<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Fórmula:C22H27FO4Cor e Forma:NeatPeso molecular:374.451,3-Bis(trimethylsilyl)urea
CAS:Produto Controlado<p>Applications 1,3-Bis(trimethylsilyl)urea (cas# 18297-63-7) is a useful research chemical.<br></p>Fórmula:C7H20N2OSi2Pureza:>85%Cor e Forma:NeatPeso molecular:204.42(1R)-(+)-a-Pinene (~80% ee)
CAS:Produto Controlado<p>Applications (1R)-(+)-α-Pinene is used in hydroboration reactions and the reduction of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, H. et al.: J. Org. Chem., 50, 1384 (1985);<br></p>Fórmula:C10H16Cor e Forma:NeatPeso molecular:136.235,8-Epoxy-13-cis Retinoic Acid(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications A metabolite of 13-cis-Retinoic Acid (R250000).<br>References Samokyszyn, V., et al.: J. Biol. Chem., 262, 14119 (1987), Oldfield, N., et al.: Drug Metabol. Dispos., 18, 1105 (1990), Samokyszyn, V., et al.: Chem. Res. Toxicol., 10, 795 (1997),<br></p>Fórmula:C20H28O3Cor e Forma:NeatPeso molecular:316.43Perfluorodecane Sulfonic Acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Perfluorodecane Sulfonic Acid, is a micropollutant found in marine organisms and waste water sludge.<br>References Wille, K., et. al.: Anal. Bioanal. Chem., 400, 1459 (2011); Arvaniti, O.S., et. al.: J. Hazard. Mater., 239, 24 (2012)<br></p>Fórmula:C10HF21O3SCor e Forma:Off-White To BlackPeso molecular:600.14Glutaurine Sodium Salt
CAS:<p>Applications Glutaurine Sodium Salt is the salt of Glutaurine (G597350) which has been observed to display antiepileptic effects with anti-amnesia properties. Mimics anxiolytic drug Diazepam (D416855).<br>References Bittner, S. et al.: Amino Acids., 28, 343 (2005); Uemura, S. et al.: Brain. res., 594, 347 (1992);<br></p>Fórmula:C7H14N2O6S•x(Na)Cor e Forma:NeatPeso molecular:254.2622997-Hydroxy-1,3-naphthalenedisulfonic Acid Dipotassium Salt
CAS:Produto Controlado<p>Applications 7-Hydroxy-1,3-naphthalenedisulfonic acid is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Fórmula:C10H6O7S2·2KCor e Forma:Off White SolidPeso molecular:380.48Hydrocinnamic Acid N-Hydroxysuccinimide Ester
CAS:Produto Controlado<p>Applications Hydrocinnamic Acid N-Hydroxysuccinimide Ester (cas# 109318-10-7) is a compound useful in organic synthesis.<br></p>Fórmula:C13H13NO4Cor e Forma:NeatPeso molecular:247.2517β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H21O5S·NaCor e Forma:NeatPeso molecular:372.414-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Cor e Forma:White To BrownPeso molecular:618.60Indoleacetic Acid-d4
CAS:Produto Controlado<p>Applications Labelled Indoleacetic Acid (I577343) has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);<br></p>Fórmula:C102H4H5NO2Cor e Forma:NeatPeso molecular:179.21Isovaleric anhydride
CAS:Produto Controlado<p>Applications Isovaleric anhydride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H18O3Cor e Forma:ColourlessPeso molecular:186.253-Sulfo-glycodeoxycholic Acid Disodium Salt
CAS:Produto ControladoFórmula:C26H41NNa2O8SCor e Forma:NeatPeso molecular:573.65Pipamazine
CAS:<p>Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.<br>References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);<br></p>Fórmula:C21H24ClN3OSCor e Forma:NeatPeso molecular:401.95N-Acetyl Sulfapyridine
CAS:Produto Controlado<p>Applications A major active metabolite related to the adverse effects of Sulfasalazine in human serum.<br>References Stenson, W., et al.: J. Clin. Invest., 69, 494 (1982), Bissonnette, E., et al.: J. Immunol., 156, 218 (1996), Hirohata, S., et al.: J. Neurol. Sci., 67, 115 (1985), Pullar, T., et al.: Br. Med. J., 290, 1535 (1985), Ireland, A., et al.: Clin. Sci., 78, 119 (1990),<br></p>Fórmula:C13H13N3O3SCor e Forma:NeatPeso molecular:291.33Boc-L-aspartic Acid β-Methyl Ester
CAS:Produto Controlado<p>Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.<br>References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)<br></p>Fórmula:C10H17NO6Cor e Forma:NeatPeso molecular:247.245Tranexamic-d2 Acid
CAS:Produto Controlado<p>Applications Tranexamic-d2 acid is deuterium labelled tranexamic acid (T714505), which is an antifibrinolytic agent that blocks lysine binding sites of plasminogen. Hemostatic.<br>References Andersson, et al.: Scand. J. Haematol. 2, 230 (1965), Melander, B., et al.: Acta Pharmacol. Toxicol., 22, 340 (1965), Bonnar, J., et al.: Br. Med. J., 313, 579 (1996), Dunn, C.J., et al.: Drugs, 57, 1005 (1999),<br></p>Fórmula:C8H13D2NO2Cor e Forma:NeatPeso molecular:159.22Docosanoic Acid Methyl Ester
CAS:<p>Applications Docosanoic Acid Methyl Ester is a long chain fatty acid, existing as a wax and is found in sunflower seeds. It can be used in biodiesel production.<br>References Soh, L. et al.: Green Chem., 13, 1422 (2011); Kanya, T.. et al.: Food Chem., 101, 1552 (2006);<br></p>Fórmula:C23H46O2Cor e Forma:Off White SolidPeso molecular:354.61Inosine-5'-monophosphate Disodium Salt Hydrate
CAS:Produto Controlado<p>Applications Inosine-5'-monophosphate Disodium Salt Hydrate is used in Raman spectra of alkali and alkaline earth metal salts of inosine 5'-monophosphoric acid.<br>References Carmona, P., et al.: J. Raman Spectrosc., 27, 817 (1996)<br></p>Fórmula:C10H11N4O8PNa·xH2OCor e Forma:NeatPeso molecular:392.17+144.12
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