Glicociência

Glcnacβ(1-2)man-α-ethylazide is a modified oligosaccharide that has been synthesized from the sugar GlcNAcβ(1-2)mannose. It is a complex carbohydrate with a high purity, which can be used as a custom synthesis. The synthesis of this product involves fluorination and saccharide methylation. The CAS number for this product is 1858224-15-3.

3'-Sialyllactose-GEL is a custom synthesis of a complex carbohydrate. It has CAS No. and is a polysaccharide that has been modified by methylation, glycosylation, and click modification. 3'-Sialyllactose-GEL is a high purity product with fluorination. It is synthetic and has a molecular weight of 1,000 Daltons.

Norfluoxetine is a selective serotonin reuptake inhibitor (SSRI) that is metabolized to the active metabolite, norfluoxetine b-D-glucuronide. The metabolism of norfluoxetine b-D-glucuronide has been shown to be inhibited by estradiol. Norfluoxetine b-D-glucuronide also exhibits antioxidant activity, which may be related to its ability to modulate expression of genes encoding antioxidant proteins. Norfluoxetine b-D-glucuronide has been found in wastewater and wastewater treatment plant effluents, suggesting this drug may have an environmental impact. The transcriptome of organisms exposed to norfluoxetine b-D-glucuronide has been studied and it was found that there are some genes that are responsive to this drug.

5-Deoxy-D-xylose is a metabolite that is produced as a byproduct of the metabolism of l-arabinose. It can be found in urine, saliva, and cerebrospinal fluid. 5-Deoxy-D-xylose has been shown to have a role in mediating the effects of nitroacetate and hydrogen fluoride on nitric oxide synthase. This compound also has an anti-inflammatory effect, which may be due to its ability to inhibit the production of neopterin. The isomers form from 5-deoxy-D-xylose are tautomeric with each other and their optical isomers are chemically different from one another. 5-Deoxy-D-xylose can exist as a cyclic form or as an open chain form.

1,6:2,3-Dianhydro-4-O-(2',3',4',6'-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-mannopyranose is a custom synthesis of an oligosaccharide that contains a saccharide. It belongs to the class of carbohydrates and can be used in research as a fluorinated complex carbohydrate for modification. This product is not intended for human or animal consumption.

1,2,3,6-Tetra-O-benzoyl-5-thio-D-glucopyranose is a monosaccharide that can be synthesized by the methylation of 1,2,3,6-tetra-O-(benzoyl) D-glucopyranose. The synthesis of this compound is accomplished by a click modification and the use of a fluoroquinolone to modify the sugar at C1. This compound has been shown to be an excellent substrate for polysaccharide and saccharide synthesis as well as fluorination. Purity levels are high with this product.

3-Pyridinylmethylbeta-D-glucopyranoside is a sugar that can be custom synthesized. It is a white to off-white crystalline powder with an odorless taste and is soluble in water. 3-Pyridinylmethylbeta-D-glucopyranoside is used in the synthesis of glycosides, saccharides, oligosaccharides, and monosaccharides. This compound can also be modified with fluorination or methylation reactions. The use of this product has been shown to produce high purity compounds for use in pharmaceuticals, agrochemicals, and other chemical industries.

6-O-Triisopropylsilyl-D-glucal is a silyl ether that can be used as a protecting group for benzyl alcohol. It is an efficient, large-scale synthesis of the benzyl alcohol and d-glucuronolactone. 6-O-Triisopropylsilyl-D-glucal accelerates the reaction by removing water as a byproduct of the reaction, simplifying the synthesis to just two steps. This product is also useful for synthesizing other products with similar structures.

Phenyl 2,3,4,6-tetra-O-benzoyl-a-D-thiomannopyranoside is a synthetic carbohydrate that can be modified with methylation, saccharide and fluorination. This product has been modified with a Click reaction to create an oligosaccharide. Phenyl 2,3,4,6-tetra-O-benzoyl-a-D-thiomannopyranoside is synthesized by the glycosylation of the sugar phenyl 2,3,4,6-tetraacetate. The CAS number for this product is 65236-83-1.

Phenyl a-D-thiogalactopyranoside is a sugar with a galactose and thioglucose residue linked by an alpha-1,6 glycosidic bond. It is obtained from the hydrolysis of starch or starch derivatives such as maltodextrin. This compound can be modified through various reactions, including fluorination, glycosylation, methylation, and modification. Phenyl a-D-thiogalactopyranoside has CAS number 5664-77-5 and molecular weight of 288.24 g/mol.

Gala1-3Gal-HSA is a modified glycan with three terminal alpha-galactoside units. It is synthesized by the modification of Gala1-3Gal (saccharide) with HSA. This product is also fluorinated, methylated and click-modified. The chemical name for this product is 3-[(2S,3S)-2,3-bis[(carboxymethyl)amino]propyl]-alpha-D-galactopyranosyl-(1→4)-O-[(carboxymethyl)(hydroxyethyl)]-.

Please enquire for more information about 1,3-o-Dibenzyl-N-acetyl-β-D-glucosamine 4,6-diacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,5,6-Tri-O-benzyl-3-benzyloxymethyl-octa-1,7-dien-3-ol is an oligosaccharide that is synthesized by the modification of a simple sugar with two benzyloxymethyl groups. It can be used as a carbohydrate in pharmaceuticals and other applications.

Lipid X is a monosaccharide precursor of E. coli lipid A. It is an N-acyl-D-glucosamine 1-phosphate where the N-acyl group is (R)-3-hydroxytetradecanoyl and carrying an additional (R)-3-hydroxytetradecanoyl, and it is a component of the cell wall of Gram-negative bacteria. Due to its physiological functions and biological properties, Lipid X can be used to treat infectious diseases, autoimmune diseases, and HIV infection. It has also been shown to inhibit the production of inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin-1β (IL-1β). This effect is due to its ability to disrupt hydrogen bonds between lipids in the cell membrane. As a biosynthetic intermediate of Lipid A, it seems to play a role in bacterial virulence and can trigger an immune response in humans, and protect against endotoxins.

Didesmethylsibutamine D-glucuronide is a custom synthesis, complex carbohydrate, Oligosaccharide, CAS No. that is modified with saccharide and Methylation. It is synthesized with Carbohydrate and sugar to produce a high purity product. It also has the following modifications: Fluorination, Synthetic.

Blood group B trisacchharide-APE-HSA is a synthetic carbohydrate that inhibits the synthesis of complex carbohydrates. The methylation of saccharides and polysaccharides can be accomplished by the addition of an amine to the 3′ hydroxyl group. In this reaction, the sugar is attached to a protein carrier (e.g., human serum albumin) via an amide bond, which prevents its degradation by proteases in the body. The modification of saccharides and polysaccharides is also accomplished through click chemistry, which is based on copper catalysis. This process involves attaching two functional groups through a copper-mediated reaction, forming a new carbon-carbon bond. Modification of saccharides and oligosaccharides can be accomplished using either chemical or enzymatic methods. Sugar modification can be achieved using high purity enzymes that have been custom synthesized for specific purposes (e.g., glycosylation). Carbohydrate modification can

2-Amino-2-deoxy-D-xylose is a metal chelator that can be used in the treatment of infections caused by bacteria. It has been shown to have synergistic effects with metaperiodate, a compound that inhibits bacterial growth by blocking the synthesis of folic acid. 2-Amino-2-deoxy-D-xylose also chelates and removes heavy metals such as mercury and lead from the bloodstream and other tissues. In addition, this drug is an efficient method for producing amino function pyrimidine nucleosides, which are precursors to DNA and RNA synthesis. The metal chelate ring is formed through dehydration of a furanose molecule with a chloride ion. This leads to an advanced carbohydrate product that contains chlorine.

Methimazole is a drug that inhibits the synthesis of thyroid hormones by blocking the action of thyroperoxidase. Methimazole thio-b-D-glucuronide is a non-toxic, water-soluble derivative of methimazole. It is used in the treatment of hyperthyroidism and thyrotoxicosis. This compound can be synthesized from methimazole by click chemistry, fluorination or glycosylation. The product can be custom synthesized with high purity and high carbohydrate content.

4'-Hydroxytrazodone b-D-glucuronide is a modification of the drug 4'-hydroxytrazodone, which is used to treat hypertension and depression. The modification prevents the degradation of 4'-hydroxytrazodone by glucuronyl transferase enzymes in the liver, prolonging its half-life. It is synthesized from the glycogen or starch of plants such as corn, wheat, or potatoes. This compound can also be found in natural sources such as honey and fruit juices.

Sucralose is a non-nutritive artificial sweetener that has no calories and is used in place of sugar. It is made from sucrose by substituting three hydrogen-oxygen groups with three chlorine atoms. The deuterium isotope, D6, was used to prepare this compound for analysis because it only emits positrons that can be detected using a PET scanner. Sucralose-d6 was shown to have high resistance to degradation due to its strong bond between the carbon and oxygen atoms in the molecule. This property makes it more stable than other sugars and carbohydrates which are subject to hydrolysis by enzymes in wastewater treatment plants. Deionized water can be used as a sample preparation solvent for sucralose-d6 because it does not contain any ions that may react with this compound.

5-Fluorouracil N-b-D-glucuronide is the major metabolite of 5-fluorouracil. It is mainly excreted in urine and bile, and has a high blood level. The glucuronide conjugate of 5-fluorouracin is hydrolyzed by beta-glucuronidase to generate 5-fluorouridine, which can be reabsorbed into the cell to form cytotoxic 5-fluoro uridine triphosphate. This process inhibits protein synthesis, leading to cell death. The half life of 5FU glucuronide is short and it needs to be constantly replaced with new doses. It has also been shown that levels of 5FU glucuronide are higher in tissues than in plasma, which may explain its inhibitory effect on tumors.

UDP-a-D-Xylose disodium is a fluorinated synthetic monosaccharide that has been synthesized to produce an oligosaccharide. It is a complex carbohydrate with glycosylation and polysaccharide modifications, which can be modified by methylation or click chemistry. This product is usually used as a custom synthesis for research purposes.

Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).