Glicociência

<p>2-AB labeled core pentasaccharide found in most N-linked oligosaccharides.  Purified from the oligosaccharide pool released from bovine serum by hydrazinolysis using a combination of HPLC and glycosidase digestion.</p>

<p>Glycosyl-donor for syntheses of mannosyl-glycoconjugates</p>

<p>Ferulic acid acyl-b-D-glucoside is a flavonoid compound that has been shown to have antioxidant properties. It is found in plants and can be synthesized by the enzyme phenylalanine ammonia-lyase. Ferulic acid acyl-b-D-glucoside is insoluble in water, but soluble in organic solvents such as ethanol and acetone. The chemical composition of ferulic acid acyl-b-D-glucoside is not well understood, but it has been shown to contain chalcone, chlorogenic acids, aldehydes, celosianin, and betanidin.</p>

<p>GT3 oligosaccharide (free acid) is a disaccharide (Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the galactose residue (Ledeen, 2009). The GT3 ganglioside is the carbohydrate moiety in the GT3 ganglioside, which is implicated in type 1 diabetes. GT3 ganglioside is expressed on pancreatic cells and is the target antigen of anti-GM3-antibodies, which contribute to the autoimmune destruction of pancreatic beta cells (Misasi, 1997). GT3 ganglioside is also abundant in lung tissues and the nervous system.</p>

<p>Monofucosyllacto-N-hexaose II is a tetraol that is used as a reagent in the synthesis of enantioenriched and synthetically tetrasaccharidic products. Monofucosyllacto-N-hexaose II can be obtained by the reaction of Grignard reagents with glucose or by stereoselective reduction of an alpha, beta unsaturated ketone. The presence of the glucose residue in Monofucosyllacto-N-hexaose II makes it an acceptor for esterification reactions. This compound has chiral centers due to its two stereogenic centers at C2 and C3, which are both beta positions on the glucose residue. Monofucosyllacto-N-hexaose II also has a free hydroxyl group at C5 that can be esterified to produce chiral esters.</p>

<p>Phenethyl glucosinolate potassium salt is a compound found in plants belonging to the Brassicaceae family. It has been shown to be highly toxic to larvae of the cabbage butterfly and other insects that feed on brassica plants. Phenethyl glucosinolate potassium salt has been shown to inhibit the development of these insects, probably by inhibiting protein synthesis in the insect's gut. The major sulfur-containing compound in this product is gluconasturtiin, which has been shown to inhibit growth of pekinensis at high temperatures. This compound also inhibits radiation-induced DNA damage and does not show significant effects on nonsignificant organisms such as yeast and mold.</p>

<p>8-methoxycarbonyl ester of Gal-a1-3(Fuc-a1-2)Gal</p>

<p>D-Galacturono-6,3-lactone is a fatty acid that is part of the glucuronolactone family and has been shown to have anti-obesity effects in vitro. D-Galacturono-6,3-lactone has been synthesized from sodium citrate and hydrochloric acid in the presence of magnesium salt, and the product was purified by crystallization. It has also been shown to inhibit aminotransferase activity and increase locomotor activity. D-Galacturono-6,3-lactone has a ph optimum of 4.5, which can be determined by an analytical method involving the measurement of hydrogen ion concentration.</p>

<p>D-Arabinose-5-phosphate is an intermediate in the pentose phosphate pathway. It is synthesized from D-xylulose-5-phosphate by xylitol dehydrogenase. D-Arabinose-5-phosphate inhibits the enzyme xylitol dehydrogenase, which converts xylulose to d-xylulose, and thus prevents the formation of 5-hydroxyisoxazole phosphate, a precursor to the synthesis of NADPH. In this way, it blocks the synthesis of NADPH, which is essential for aerobic metabolism. This inhibition leads to a decrease in ATP production and consequently cell death.</p>

<p>Methyl 2-deoxy-L-ribofuranoside is an intermediate in the synthesis of l-arabinose. It can be obtained by the reaction of methyl 2,3-dideoxy-D-ribofuranoside with pivaloyl chloride. The antiviral activity of this compound has been shown by its ability to inhibit the replication of influenza A virus. Methyl 2-deoxy-L-ribofuranoside is a fluorinating agent that can be used for the synthesis of oligosaccharides and nucleosides. This intermediate also serves as a substrate for a number of organic reactions, including regioselective and stereoselective chlorination.</p>

<p>1,2,3-Tri-O-methyl-D-glucopyranoside is a custom synthesis and modification of the natural product 1,2,3-tri-O-methyl-D-mannopyranoside. The compound was synthesized by fluorination of the 3' hydroxyl group followed by methylation of the 2', 3' hydroxyl groups to form a triol. This sugar was then glycosylated with D-glucose to produce an oligosaccharide. 1,2,3 - Tri -O - methyl - D - glucopyranoside is a natural product that can be found in plants such as barley and wheat. It has been shown to have antiinflammatory properties.</p>

<p>Onitin 2'-O-glucoside is a sugar that is custom synthesized and purified. It is a modification of oligosaccharides, complex carbohydrates, and polysaccharides. Onitin 2'-O-glucoside is an Oligosaccharide Carbohydrate which can be used in the synthesis of high purity monosaccharides and methylations. It also has the ability to form glycosylation with saccharides, such as glucose or fructose. This product can also be fluorinated to produce saccharides that are water soluble.</p>

<p>2-Acetamido-2-deoxy-D-glucopyranosyl serine is a compound that belongs to the class of coumarins and monosaccharides. It contains a nitro group and a heterocycle, making it a unique and versatile molecule. This compound has been studied for its various properties, including its interaction with liver microsomes and its ability to undergo crystallization. Additionally, 2-Acetamido-2-deoxy-D-glucopyranosyl serine has shown promising effects on TGF-beta activation and has been found to inhibit aldehyde formation in trichloroacetic acid solutions. This compound also exhibits interactions with other molecules such as pyrazine, ofloxacin, and famotidine. Its diverse characteristics make it an intriguing compound for further research and potential applications in various fields.</p>

<p>Quaternization of the primary amine in N-Trimethylchitosan increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. N-Trimethylchitosan is soluble in water and ethanol, making it ideal for use in biotechnology applications.The degree of quaternization is 30-70%</p>

<p>5-azido-5-deoxy-D-arabinose is a compound derived from Aquilaria sinensis that has various biological activities. It has been shown to modulate transmembrane conductance by interacting with fatty acid-binding proteins and divalent metal ions. Additionally, it can regulate the activity of potassium channels, which play a crucial role in cellular function. 5-azido-5-deoxy-D-arabinose is known for its reactive properties and can form covalent adducts with nucleophilic residues in proteins, affecting their structure and function. This compound has also been studied for its potential therapeutic applications, such as enhancing the delivery of iron sucrose through electrode-based systems or improving the bioavailability of drugs like ketorolac or creatine. Furthermore, 5-azido-5-deoxy-D-arabinose exhibits interesting carbohydrate chemistry, making it a valuable tool for carbohydrate synthesis and modification. Its diverse characteristics and unique properties make it an intriguing compound for further</p>

<p>Please enquire for more information about N-(Formylamidino)-N-b-D-ribofuranosylurea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is a carbohydrate that has been shown to bind to the lectin domain of the human insulin receptor. This binding is thought to modulate the activity of this protein. The carbohydrate has also been shown to inhibit the uptake of galactose by pancreatic beta cells in vitro. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is postulated to have anti cancer properties and may be used as a blocker for tumor growth.</p>

<p>D-Glucosamine-3,4,6-tri-O-sulphate trisodium salt is a high purity and custom synthesis of D-glucosamine. It is a sugar with click modification and fluorination. It has CAS No. 157297-03-5 and it is synthesized from glycosylation, methylation, and modification. It has a molecular weight of 517.85 g/mol and the chemical formula C9H14N2O12S3NaO6. Glucosamine is an oligosaccharide that can be found in many complex carbohydrates such as chitin or cellulose.</p>

<p>Tetradecyl b-D-maltopyranoside is a crystalline polymer of high molecular weight that is made up of repeating units of tetradecyl b-D-maltose. It has a lamellar morphology and can be sectioned with techniques such as electron microscopy, X-ray diffraction, and differential scanning calorimetry. Tetradecyl b-D-maltopyranoside is a metastable form of the compound. It has been found in nature in the form of the monomer unit, tetradecyl maltosyl (tetramethyleneglycol) b-d-maltoside. In order to produce this compound as a polymer, it must first be heated to about 160°C for several hours, which causes the monomers to assemble into chains of tetrahedrons. The properties of tetradecyl b-D-maltopyranoside depend on its environment</p>

<p>N-Oleoyl-N-Methyltaurine sodium salt is a glycol ether that has been shown to be an effective transport inhibitor for fatty acids. It inhibits the growth of bacteria and fungi by interfering with the cell membrane lipid synthesis. N-Oleoyl-N-Methyltaurine sodium salt also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Tetragalacturonic acid (α-1,4 galacturonotetraose) is derived from pectin or pectic acid by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Globotriose-sp-biotin is a custom synthesis that contains a fluorinated, methylated, and modified monosaccharide. It is a synthetic oligosaccharide with glycosylation at the reducing end. Globotriose-sp-biotin can be used in the modification of polysaccharides and complex carbohydrates to improve their bioactivity. This product has a CAS number of 127798-73-5 and is listed as an Oligosaccharide under Glycosylations in the Carbohydrate section.</p>

<p>2-Acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-4-fluoro-D-glucopyranose is a high purity synthetic glycosylate with a custom synthesis. It is an oligosaccharide that has been modified for fluorination and methylation. This product is used as an intermediate in the production of complex carbohydrates.</p>

<p>Methyl 2-deoxy-5-O-toluoyl-L-ribofuranoside is a high purity, custom synthesis, methylated, Glycosylation and Oligosaccharide. It has CAS No. 676598-19-9 and is Glycosylated and Methylated. This complex carbohydrate is a synthetic, monosaccharide or saccharide that can be modified with fluorination, Click modification or glycosylation.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Neutral difucosylated hexasasaccharide naturally present in human breast milk</p>

<p>6-Chloro-6-deoxy-D-mannose is a naturally occurring sugar that is found in the spermatozoa of many animals. It is a mannose derivative that has been shown to be an inhibitor of the enzyme glyceraldehyde 3-phosphate dehydrogenase, which plays an important role in energy metabolism and isomerization of 6-phosphate to glucose-1 phosphate. This property may be responsible for its contraceptive effects. The drug also inhibits phosphoglucomutase and enhances the transfer of glucose from the liver to other tissues, increasing blood glucose concentrations. 6-Chloro-6 deoxy mannose also has antifertility effects in rats by inhibiting transfer of spermatozoa through the female reproductive tract.</p>

<p>Building block for chemical modification of GlcU, including glucuronylation</p>

<p>β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a synthetic, nonsteroidal estrogen with a high affinity for the human estrogen receptor. It is used in the treatment of various types of breast cancer and as hormone replacement therapy. β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a part of the drug class selective estrogen receptor modulators (SERMs). The compound has been shown to have antiestrogenic activity through its ability to compete with estradiol for binding to the estrogen receptor. This compound also has some antiandrogenic effects and can inhibit sex hormone binding globulin (SHBG), leading to increased levels of free testosterone in blood plasma.</p>

<p>Please enquire for more information about 3'-methoxy apiin;Chrysoeiol-7-(2-O-apiosylglucoside) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cellulose is a linear polysaccharide of β 1-4 linked glucose residues. The polysaccharide chains are bundled as microfibrils in cell walls and provide the essential structural components within growing plants. Each microfibril exhibits a high degree of three-dimensional internal bonding resulting in a crystalline structure that is insoluble in water, resistant to reagents and very strong. The crystalline region of cellulose is isolated to produce microcrystalline cellulose. Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production.</p>

<p>Please enquire for more information about (Hydroxypropyl)methyl cellulose, viscosity 5 cP 80%-120%, 2% aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Benzamido-2-deoxy-D-glucopyranose is a synthetic, inexpensive, and non-toxic compound that has antibiotic properties. It is used as a reagent for the sulfonylating of aromatic rings and as an intermediate in the synthesis of other compounds. 2-Benzamido-2-deoxy-D-glucopyranose can be radiolabeled with carbon or fluorine atoms to form a resonance labeled probe that can be used in magnetic resonance spectroscopy.</p>

<p>2-Deoxy-D-glucono-1,5-lactone is a crystalline compound that is isolated from the hydrolysis of D-gluconic acid. This compound has been found to be a diastereoisomeric product with a lactone ring and an epimerization process. It can also be synthesized by reacting epichlorohydrin with potassium hydroxide in the presence of a hydroxy group. 2DG is an elimination product of 2-deoxyglucose and has been shown to have antihyperglycemic effects due to its ability to inhibit glucose synthesis in the liver and muscle cells. This compound also inhibits protein synthesis in bacteria, which may lead to cell death.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Gamma-cyclodextrin (γ-CD) is a cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarooctaose is reported to have potential for novel cosmeceuticals.</p>

<p>Polysorbate 60 is a polyoxyethylene-polyoxypropylene block copolymer that is composed of two different saturated fatty acid chains. It has been used as a surfactant and stabilizer in the manufacture of pharmaceuticals, foods, cosmetics, and other products. Polysorbate 60 has been shown to inhibit the growth of epidermal cells by binding to epidermal growth factor (EGF) receptors on the cell surface. The effects of polysorbate 60 are also mediated through hydrogen bonding with the EGF receptor. The pharmacokinetic properties of polysorbate 60 have been studied in vitro using human serum. This polymer is used as an excipient in solid dispersions for oral administration and can be administered intravenously or subcutaneously. Polysorbate 60 is chemically stable at acidic pH levels and hydrochloric acid does not affect its structure. Polysorbate 60 also has protease activity against trypsin at high temperatures,</p>

<p>Trehalose 6-octanoate is a modified form of trehalose that has been synthesized and fluorinated. It is a monosaccharide, which means it is one of the simplest forms of sugar. Trehalose 6-octanoate is an oligosaccharide, which means it is a sugar molecule made up of several smaller sugar molecules. This sugar can be modified to include methyl groups, making it a polysaccharide. Polysaccharides are complex carbohydrates that can often be found in plants or animals. Trehalose 6-octanoate is used in the modification of proteins and lipids for the production of pharmaceuticals and other products.</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>Dipyridamole di-O-b-D-glucuronide is a fluorinated oligosaccharide that has been synthesized using the click chemistry reaction. It is a monosaccharide that has been glycosylated and modified with methyl groups to produce a high purity product. The carbohydrate consists of one or more sugar units linked by glycosidic bonds. Carbohydrates are classified by their number of sugar units and by the presence of other chemical groups such as phosphate, sulfate, or hydroxyl. This product is also used in the synthesis of complex carbohydrates and polysaccharides.</p>

<p>a-D-Mannopyranosyl amine is a synthetic product that is used as a sugar donor in glycosylation reactions. It can be custom synthesized to suit the needs of the customer. The chemical structure contains a methyl group and an oxygen atom, which are both in their highest oxidation state. This product is not intended for use as a food additive or dietary supplement.</p>

<p>Methyl 2-azido-3,4,6-tri-O-acetyl-2-deoxy-bD mannoside is a custom synthesis that can be modified to suit the needs of the customer. It is an oligosaccharide and polysaccharide that has been modified with methylation and glycosylation. This product has CAS No. 97604-59-6 and is available for purchase in high purity with a purity level of at least 95%. Methyl 2-azido-3,4,6-triO acetyl -2 deoxy b D mannoside has been fluorinated to create a synthetic sugar.</p>

<p>1,2,3,4,6-Penta-O-acetyl-D-galactopyranose is an analog of the natural pentoses that binds to the mitochondrial membrane and inhibits the production of pro-inflammatory cytokines. This drug has been shown to inhibit the binding of lysophosphatidic acid (LPA) to its receptor by substituting for LPA in this binding site. 1,2,3,4,6-Penta-O-acetyl-D-galactopyranose also inhibits the expression of proinflammatory cytokines such as interleukin 6 (IL6) and IL1β in a dose dependent manner. This drug is also capable of inhibiting phosphotungstic acid from binding to a monolayer surface and can be used as a glycopolymer for cell culture. It has been shown that 1,2,3,4,6-Penta-O-acetyl</p>

<p>In plants and algae, the two main galactolipids, monogalactosyldiacyglycerol (MGDG) and digalactosyldiacyglycerol (DGDG), are synthesized by galactosyltransferases in the plastid envelope. They have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO)</p>

<p>Please enquire for more information about Galacto-RGD trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl b-D-fructofuranoside is a chemical compound that is used in the production of esters and fatty acids. Methyl b-D-fructofuranoside is produced by a dehydration reaction between two molecules of acetone. The product of this reaction, methyl b-D-fructopyranoside, can be broken down into two molecules of acetone and one molecule each of methyl alcohol and carbon dioxide. This process is called alkylation. Furanocoumarin derivatives are often found in plants such as asperulosidic acid and quinquefasciatus. These compounds are found in many species of plant, but they are most concentrated in the roots of these plants because they are more metabolically active there than other parts of the plant. Environmental pollution can lead to high concentrations of furanocoumarins in plants, which can have toxic effects on organisms that come into contact with them.</p>

<p>1,2,3,4-Tetra-O-acetyl-D-glucuronide methyl ester is a lactone that can be used as a precursor for the synthesis of various types of compounds. The chemical structure was determined by high-resolution x-ray diffraction to be a planar molecule with two conformations: one where the four acetyl groups are on different sides and another where they are all on the same side. The latter conformation is more stable due to the dihedral angle between the hydroxyl group and carbonyl group. This compound is an intermediate in synthesizing 2-(4'-hydroxybenzoyl)-1,2,3,4-tetra-O-acetyl-.alpha.-D-.beta.-D glucopyranoside methyl ester by reacting with 3-(3'-azido)benzaldehyde. The single crystal x-ray diffraction study revealed that this compound has a conformation</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Benzyl 2-acetamido-2-deoxy-α-D-glucopyranoside is a synthetic compound with a molecular weight of 342.45 g/mol. It is a white to pale yellow crystalline solid that is soluble in water and methanol. The chemical formula for this compound is C12H14N2O6 and its structural formula is represented as CH2(COOCH3)COOC8H11O6. The CAS number for this compound is 13343-62-9, and the IUPAC name for it is benzyl 2-(2-acetamido)-2,3,4,5,6-pentaacetoxy αDglucopyranoside. This compound has been used in methylation reactions and click chemistry applications due to its ability to form stable carbonyl bonds with other molecules. Benzyl 2-(2-acetamido)-2,3,4,5,6</p>