Canabinóides
Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.
Foram encontrados 299 produtos de "Canabinóides"
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1,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS:<p>1,2,3,9-Tetrahydro-4H-carbazol-4-one is a cyclic ketone compound, which can be synthesized through various organic reactions involving appropriate precursors. It is often derived from indole-based substrates through catalytic hydrogenation, allowing the formation of its stable tetrahydro structure with a retained core carbazole skeleton.</p>Fórmula:C12H11NOPureza:Min. 95%Cor e Forma:PowderPeso molecular:185.23 g/molC2
CAS:<p>Positive allosteric modulator (PAM) of cannabinoid receptors CB2. The C2 modulator is the first synthetic PAM of CB2 receptors with antinociceptive properties, which were observed in a mouse model of neuropathic pain.</p>Fórmula:C21H24BrFN2O2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:435.33 g/molGW 833972A hydrochloride
CAS:<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Fórmula:C18H13ClF3N5O·HClPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:444.24 g/molGW 833972A
CAS:<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Fórmula:C18H13ClF3N5OPureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:407.78 g/molACEA, 5mg/ml solution in ethanol
CAS:<p>Cannabinoid type 1 (CB1) receptor agonist. Anti-depressant activity demonstrated in vivo alone, as well as enhancing the effect of fluoxetine. In the brain, ACEA activates CB1 receptors expressed in the mitochondria of neuronal cells to elicit neuroprotective effects. This is mediated by inducing glycogen synthase kinase-3β (GSK-3β) phosphorylation and inhibiting the opening of mitochondrial permeability transition pore (MPTP).<br>Sold by weight of solid</p>Fórmula:C22H36ClNOPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:365.98 g/molAnandamide
CAS:<p>Anandamide is an endogenous cannabinoid, which is a bioactive lipid mediator primarily found in the brain and peripheral organs. It is synthesized from membrane phospholipid precursors through enzymatic pathways, primarily involving the enzyme N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD). Anandamide acts as a ligand for cannabinoid receptors, mainly the CB1 receptor located in the central nervous system, and the CB2 receptor found in peripheral tissues.</p>Fórmula:C22H37NO2Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:347.53 g/molCannabichromenic Acid
CAS:<p>Cannabichromenic acid is a non-psychoactive phytocannabinoid and a precursor of cannabichromene1 which toxicological and pharmacological properties are unknown. Due to its structural similarity to cannabichromene, it is thought to reportedly exert anti-analgesic and anti-inflammatory activity.</p>Fórmula:C22H30O4Pureza:Min. 95%Peso molecular:358.47 g/molCannabigerovarinic acid
CAS:Produto Controlado<p>Cannabigerovarinic acid is a phytocannabinoid and the precursor to tetrahydrocannabivarinic acid, cannabidivarinic acid, and cannabichromevarinic acid1. No in vitro or in vivo pharmacological and toxicological studies have been conducted on cannabigerovarinic acid.</p>Fórmula:C20H28O4Pureza:Min. 95%Peso molecular:332.43 g/molrel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-na phthalenedicarboxamide
CAS:<p>rel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-naphthalenedicarboxamide is a synthetic chemical compound, which is derived through targeted organic synthesis and structural optimization efforts. Its source lies in advanced laboratory methodologies designed to enhance specific pharmacological properties. The mode of action is expected to involve selective interaction with particular molecular targets, potentially modulating distinct pathways related to cellular function or signaling processes.</p>Fórmula:C36H34Br2N2O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:782.47 g/molAPD 371
CAS:<p>A selective cannabinoid receptor type 2 (CB2) agonist. Commonly, CB2 agonists induce receptor internalization, which results in desensitization and tachyphylaxis. However, APD 371 mediates efficient recycling of internalized receptors back to the plasma membrane and thus sustains analgesic effects, upon subchronic treatment, in an osteoarthritis pain model in vivo.</p>Fórmula:C18H23N5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:357.41 g/molAbnormal 1''-Hydroxycannabidiol
Produto ControladoFórmula:C21H30O3Cor e Forma:NeatPeso molecular:330.4615-(4-Hydroxypentyl)-1,3-benzenediol
CAS:Produto Controlado<p>Applications 5-(4-Hydroxypentyl)-1,3-benzenediol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Fórmula:C11H16O3Cor e Forma:NeatPeso molecular:196.24Cannabigerovarinic acid
CAS:Carboxylic acid with phenol functionFórmula:C20H28O4Pureza:≥ 90.0 % (HPLC)Cor e Forma:PowderPeso molecular:332.43Dehydroabiethylamine
CAS:<p>Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.</p>Fórmula:C20H31NPureza:98.79%Cor e Forma:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidPeso molecular:285.472-[(9Z)-9-Octadecenyloxy]-1,3-propanediol
CAS:Produto Controlado<p>Applications 2-[(9Z)-9-Octadecenyloxy]-1,3-propanediol, which is an endogenous cannabinoid receptor ligand.<br>References Suhara, Y. et al.: Chem. Pharm. Bull., 48, 903 (2000);<br></p>Fórmula:C21H42O3Cor e Forma:NeatPeso molecular:342.561-(3,5-Bis(benzyloxy)phenyl)pentan-1-ol
CAS:Produto ControladoFórmula:C25H28O3Cor e Forma:NeatPeso molecular:376.491-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications (Z)-1-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one is a reagent in the synthesis of 3''-Hydroxycannabidiol (H824825) which is a major constituents in marijuana. 3''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Fórmula:C25H24O3Cor e Forma:NeatPeso molecular:372.46Ethyl 2-Oxopentanoate
CAS:Produto Controlado<p>Applications Ethyl 2-oxopentanoate is used as a reagent to synthesize selective CB1 cannabinoid receptor antagonists. Ethyl 2-oxopentanoate is also used to synthesize derivatives of iminodiacid, an inhibitor of angiotensin converting enzyme.<br>References Lange, J., et al.: J. Med. Chem., 48, 1823 (2005); Vincent, M., et al.: Tetrahedron Lett., 23, 1677 (2982)<br></p>Fórmula:C7H12O3Cor e Forma:NeatPeso molecular:144.17(1S,4R)-1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
CAS:Produto Controlado<p>Applications 1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol is an acetal reagent used in the synthesis of desoxy cannabidiols and THC (T293202) related psychoactive compounds. It is formed from (+)-Limonene using a photosynthesized O2 transfer.<br>References Wilkinson, S. et al.: Tetrahedron Lett., 54, 52 (2013);<br></p>Fórmula:C10H16OCor e Forma:NeatPeso molecular:152.23Cannabigerorcinic Acid
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Cannabigerorcinic Acid is a compound that takes part in the biosynthesis of daurichromenic acid synthase which is active in anti-HIV biosynthesis.<br>References Iijima, M. et al.: Plant Phys., 174, 2213 (2017);<br></p>Fórmula:C18H24O4Cor e Forma:NeatPeso molecular:304.382-Arachidonyl glycerol
CAS:<p>2-Arachidonyl glycerol is an endogenous cannabinoid receptor agonist, which is derived from arachidonic acid present in cellular membranes. It functions as a signaling lipid and plays a critical role in the endocannabinoid system, which is a complex network of receptors and ligands involved in maintaining physiological homeostasis.</p>Fórmula:C23H38O4Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:378.55 g/molS-777469
CAS:<p>S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.</p>Fórmula:C23H27FN2O4Cor e Forma:SolidPeso molecular:414.47AM-6538
CAS:<p>AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.</p>Fórmula:C26H25Cl2N5O4Cor e Forma:SolidPeso molecular:542.41NIDA 41020
CAS:<p>NIDA 41020 is a CB1 receptor antagonist.</p>Fórmula:C23H24Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:459.37PGN36
CAS:<p>PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43LEI-101
CAS:<p>LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.</p>Fórmula:C23H25FN4O4SPureza:98%Cor e Forma:SolidPeso molecular:472.53GPR55 agonist 3
CAS:<p>Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.</p>Fórmula:C19H16F4N4Cor e Forma:SolidPeso molecular:376.35MJ 15
CAS:<p>MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.</p>Fórmula:C23H17Cl3N4OPureza:99.63%Cor e Forma:SolidPeso molecular:471.77LH 21
CAS:<p>LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.</p>Fórmula:C20H20Cl3N3Cor e Forma:SolidPeso molecular:408.75AM6545
CAS:<p>AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.</p>Fórmula:C26H23Cl2N5O3SPureza:97.03%Cor e Forma:SolidPeso molecular:556.46CB1-IN-2
CAS:<p>CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.</p>Fórmula:C17H19Cl2N5OCor e Forma:SolidPeso molecular:380.27AM404
CAS:<p>AM404 is a cannabinoid reuptake inhibitor and a TRPV (1) activator with neuroprotective and anticancer activities that blocks anandamide transport.</p>Fórmula:C26H37NO2Cor e Forma:SolidPeso molecular:395.58PM226
CAS:<p>CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.</p>Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49CB1/2 agonist 4
CAS:<p>CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.</p>Fórmula:C27H45NO3Cor e Forma:SolidPeso molecular:431.65Arvanil
CAS:<p>Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.</p>Fórmula:C28H41NO3Pureza:99.49%Cor e Forma:SolidPeso molecular:439.63COR167
CAS:<p>COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.</p>Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61CB1R Allosteric modulator 4
CAS:<p>Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.</p>Fórmula:C20H17N3O2SCor e Forma:SolidPeso molecular:363.43GAT228
CAS:<p>GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].</p>Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39ANEB-001
CAS:<p>ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.</p>Fórmula:C22H24ClF3N2O2Cor e Forma:SolidPeso molecular:440.89UCM710
CAS:<p>UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).</p>Fórmula:C19H34O3Pureza:98%Cor e Forma:SolidPeso molecular:310.47O-2093
CAS:<p>anandamide uptake inhibitor</p>Fórmula:C34H43Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:584.62CID1172084
CAS:<p>CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.</p>Fórmula:C23H18FN5O2S2Cor e Forma:SolidPeso molecular:479.55LBP-1
CAS:<p>LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.</p>Fórmula:C23H29ClN6O3Cor e Forma:SolidPeso molecular:472.97COR 170
CAS:<p>inverse agonist of CB2 receptors</p>Fórmula:C31H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:468.63CB1R Allosteric modulator 1
CAS:<p>CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.</p>Fórmula:C24H24ClN3OCor e Forma:SolidPeso molecular:405.92Virodhamine trifluoroacetate
CAS:<p>Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.</p>Fórmula:C24H38F3NO4Pureza:98%Cor e Forma:SolidPeso molecular:461.56
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