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Canabinóides

Canabinóides

Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.

Foram encontrados 299 produtos de "Canabinóides"

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  • RVD-Hpα

    CAS:
    <p>N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>
    Fórmula:C65H105N19O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1424.66
  • Zevaquenabant

    CAS:
    <p>Zevaquenabant (S-MRI-1867): oral CB1/iNOS antagonist combatting obesity-induced CKD.</p>
    Fórmula:C25H21ClF3N5O2S
    Cor e Forma:Solid
    Peso molecular:547.98
  • Δ8-THC methyl ether

    CAS:
    <p>Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.</p>
    Fórmula:C22H32O2
    Cor e Forma:Solid
    Peso molecular:328.49
  • NESS 0327

    CAS:
    <p>NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.</p>
    Fórmula:C24H23Cl3N4O
    Pureza:99.78%
    Cor e Forma:Solid
    Peso molecular:489.82
  • (R)-Zevaquenabant


    <p>(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.</p>
    Cor e Forma:Odour Solid
  • CB1R agonist 1


    <p>CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.</p>
    Fórmula:C20H18F3N3O3S
    Cor e Forma:Solid
    Peso molecular:437.435
  • 8β-Hydroxy-exo-THC

    CAS:
    <p>8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.</p>
    Fórmula:C21H30O3
    Cor e Forma:Solid
    Peso molecular:330.46
  • Hemopressin(rat)

    CAS:
    <p>Peptide inhibitor for ep24.15, neurolysin &amp; ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain &amp; food intake.</p>
    Fórmula:C53H77N13O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1088.27
  • exo-Tetrahydrocannabivarin

    CAS:
    <p>exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.</p>
    Fórmula:C19H26O2
    Cor e Forma:Solid
    Peso molecular:286.41
  • (±)-9-Nor-9α-hydroxy Hexahydrocannabinol

    CAS:
    <p>(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.</p>
    Fórmula:C20H30O3
    Cor e Forma:Solid
    Peso molecular:318.45
  • CB2 receptor agonist 9

    CAS:
    <p>CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>
    Fórmula:C16H23N3O2S
    Cor e Forma:Solid
    Peso molecular:321.44
  • TRPV1/CB2 agonist 1


    <p>TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.</p>
    Cor e Forma:Odour Solid
  • δ8-THC acetate

    CAS:
    <p>Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.</p>
    Fórmula:C23H32O3
    Cor e Forma:Solid
    Peso molecular:356.5
  • VIP36


    <p>VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.</p>
    Fórmula:C27H35FN6O4
    Cor e Forma:Solid
    Peso molecular:526.603
  • Cannabidivarinic acid

    CAS:
    <p>Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.</p>
    Fórmula:C20H26O4
    Cor e Forma:Solid
    Peso molecular:330.42
  • Δ8-THC-C8

    CAS:
    <p>Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.</p>
    Fórmula:C24H36O2
    Cor e Forma:Solid
    Peso molecular:356.54
  • CB2R/FAAH modulator-2

    CAS:
    <p>CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.</p>
    Fórmula:C24H33NO2
    Pureza:99.15%
    Cor e Forma:Soild
    Peso molecular:367.52
  • CB2 receptor agonist 2

    CAS:
    <p>CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.</p>
    Fórmula:C30H36N2O4
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:488.62
  • APP-FUBINACA

    CAS:
    <p>APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.</p>
    Fórmula:C24H21FN4O2
    Cor e Forma:Solid
    Peso molecular:416.45
  • Drinabant

    CAS:
    <p>Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.</p>
    Fórmula:C23H20Cl2F2N2O2S
    Pureza:99.8%
    Cor e Forma:Solid
    Peso molecular:497.38