Lípidos

Applications 2-Stearoyl-rac-glycerol is a biomarker of metabolic responses to hepatotoxicants and carcinogens.
References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006); Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007)

Applications A labelled metabolite of Cholesterol.
References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),

Applications An oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);

Applications A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),

Applications 3-Hydroxy-7,12-diketocholanoic Acid is a bile acid salt as biosurfactants.
References Posa, M., et al.: Steroids, 86, 16-25 (2014)

Applications Food preservative, having the ability to form complexes with starch, retarding its retrodegradation during storage.
References Yu, S., et al.: J. Agric. Food Chem., 54, 4482 (2006),

Applications 5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies.
References Tohma, M., et al.: Steroids, 44, 47 (1984); Kok, E., et al.: J. Biol. Chem., 256, 6155 (1981); Back, P., et al: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 354, 83 (1973); Javitt, N., et al.: J. Biol. Chem,, 261, 12486 (1986);

Applications Δ5-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.
References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)

Applications α-Muricholic Acid is an bile acid found in urine. Studies have linked α-Muricholic in the understanding of the complex signaling pathways of hepatic lipid abnormalities with type 2 diabetes and a treatment target for this condition.
References Haeusier, R.A., et al.: Cell. Metabolism., 15, 65 (2012); Chen, K.H., et al.: Am. J. Physiol., 301, E853 (2011);

Stability Moisture Sensitive
Applications Lecithin has emulsification and lubricant properties, and is a surfactant.
References Shah, D.: J. Colloid and Interface Sci., 37, 744 (1971); Scholfield, C.: J. Am. Oil. Chem. Soc., 58, 889 (1981)

Stability Hygroscopic
Applications rac 1-Oleoyl Glycerol is a monoglyceride. These fatty acid esters are useful for the improvement of texture and flavor of beverages.
References Lee, T.-H., et al.: J. Nat. Prod., 72, 1960 (2009)

Applications Glycolithocholic-2,2,4,4-d4 Acid (CAS# 2044276-16-4) is a useful isotopically labeled research compound.

Applications The 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.
References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),

Stability Hygroscopic
Applications Glycocholic-2,2,4,4-d4 Acid was an analyte found in serum bile acids. Potential application for diagnosis of pediatric liver and intestinal diseases in humans.
References Fu, X., et al.: Clin. Chem. Lab. Med., 58, 787 (2020)

Applications (3β)-3,25-Dihydroxycholest-5-en-7-one is a useful synthetic intermediate in the synthesis of 3β,7α,25-Trihydroxycholest-5-ene (T795075); a potent agonist of GPR183 that induces specific activation of the receptor.
References Antunes, L., et al.: Antimicrob. Agents. Chemtherap., 55, 1494 (2011); Schwarz, M., et al.: J. Cin. Invest., 106, 1175 (2000); Zhang, J., et al.: BIochem. J., 322, 175 (1997)

Applications Ostreasterol is a marine steroid, and also a derivative compound of hydroxycholesterol (H918040), which functions as the main cholesterol elimination product of the brain and was found to be increased in serum of Alzheimer patients.
References Kolsch, H., et al.: J. Neural. Transm., 108, 475 (2001); Gamba, P., et al.: Aging. Cell., 10, 403 (2011); Seet, R.C.S., et al.: Free. Rad. Biol. Med., 48, 560 (2010);

Stability Hygroscopic
Applications 1-O-Octadecanoyl-sn-glycerol is a monoacylglycerol (MAG) based saturated fatty acid derivative.
References Garcia, P. et al.: J. Sep. Sci., 34, 999 (2011); Takagi, T. et al.: LIpids, 25, 398 (1990);

Applications 11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex.
References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009); Bailey, M., et al.: J. Immunol., 182, 7888 (2009); Brunton, P., et al.: J. Neurosci., 29, 6449 (2009); Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009)