Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2634 produtos de "Nucleotídeos"
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2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine
CAS:2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine is a protected nucleoside derivative that can potentially be used as an intermediate in the chemical synthesis of nucleoside analogs, especially for RNA or DNA oligonucleotides. This compounds has a 2,6-Diaminopurine – a purine analog structurally similar to adenine but with an additional amino group at the 2-position and a β-D-ribofuranosyl. The 3′ and 5′ hydroxyl groups of the ribose are protected with a bulky 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS) group. This is a silyl protecting group often used to block reactivity during nucleoside synthesis.Fórmula:C22H40N6O5Si2Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:524.77 g/mol2'-Deoxy-2'-fluoroguanosine
CAS:<p>2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.</p>Fórmula:C10H12FN5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:285.23 g/molDeoxyribonucleic acid low molecular weight from salmon sperm
CAS:<p>This low molecular DNA (deoxyribonucleic acid) from salmon sperm is a fragment that is an effective indicator of the presence of guanine in urine samples, and can be used to detect lipoperoxidation in animal hemocytes. It has also been shown to be a sublethal oxidative stress agent for human urine, which induces irreversible oxidation in the enzyme activities of signal detection. According to some recent research studies, this product is being investigated as an environmental pollutant indicator and could be used as an effective wastewater treatment method.</p>Cor e Forma:Powder3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS:Used as a protected adenosine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group is a bulky, acid-labile protecting group specifically designed to protect the 3' and 5' hydroxyl groups of ribonucleosides during RNA oligonucleotide synthesis.Fórmula:C22H39N5O5Si2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:509.76 g/mol2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution
CAS:2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution, is a synthetic nucleotide analog. It has potential application in antiviral research, particularly for studying RNA-dependent RNA polymerase (RdRP) activity in RNA viruses. It mimics the natural cytidine triphosphate (CTP) but includes a 2'-C-methyl modification on the ribose sugar.Fórmula:C10H18N3O14P3·4C6H15NPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:901.94 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS:<p>2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.</p>Fórmula:C35H37N5O6Pureza:Min. 95%Cor e Forma:Off-White To Light (Or Pale) Yellow SolidPeso molecular:623.72 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS:<p>5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.</p>Fórmula:C34H38N2O9Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:618.67 g/mol9-(2',3',5'-Tri-O-benzyl-β-D-arabinofuranosyl)adenine
CAS:9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is a nucleoside that has shown anticancer and antiviral properties. It inhibits replication of DNA and RNA in cells, which may be due to its ability to inhibit the synthesis of deoxyribonucleotides and ribonucleotides. This compound is synthetically produced from 2',3',5'-tri-O-benzyl b-D-arabinofuranosyl chloride and adenine monophosphate (AMP). 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is also known as arabinoside A.Fórmula:C31H31N5O4Pureza:Min. 95%Peso molecular:537.61 g/mol5'-Deoxythymidine
CAS:<p>5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.</p>Fórmula:C10H14N2O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:226.23 g/molβ-Nicotinamide adenine dinucleotide
CAS:<p>Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.</p>Fórmula:C21H27N7O14P2Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:663.43 g/molUridine 5'-triphosphate dihydrate trisodium salt
CAS:<p>Uridine 5'-triphosphate dihydrate trisodium salt is a nucleotide that is involved in the synthesis of RNA. This product has been used as a supplement to promote healthy eyes and skin, as well as to treat Alzheimer's disease. It has been shown to be an efficient method for the detection of active substances by hydrophilic interaction chromatography (HILIC). The HILIC method involves separating molecules based on their hydrophobic or hydrophilic properties, which are determined by the ionic strength of the solution. Uridine 5'-triphosphate dihydrate trisodium salt binds with chloride ions, which prevents it from binding with other organic compounds. The chloride ions then serve as an end point that can be detected using ultraviolet light.</p>Fórmula:C9H12N2O15P3·3Na·2H2OPureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:586.12 g/molN6,3'-O-Dibenzoyl-2'-deoxyadenosine
CAS:<p>N6,3'-O-Dibenzoyl-2'-deoxyadenosine is a nucleoside that is used as a biochemical reagent in molecular biology. N6,3'-O-Dibenzoyl-2'-deoxyadenosine has been shown to be an inhibitor of the enzyme phosphodiesterase and also binds to DNA. This compound has been shown to have antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Clostridium perfringens. The lipophilicity of this compound allows it to cross the cell membrane and cleave DNA at the site of replication. N6,3'-O-Dibenzoyl-2'-deoxyadenosine is an analog of 6,4’-dihydroxybenzophenone (DBP) and can be synthesized from DBP by reacting with dibenzoyl chloride in chloroform</p>Fórmula:C24H21N5O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:459.47 g/molN4-Benzoyl-2'-deoxycytidine
CAS:N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.Fórmula:C16H17N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:331.33 g/mol2-Aminoperimidine hydrochloride
CAS:2-Aminoperimidine hydrochloride is the hydrochloride salt of 2-aminoperimidine, a polycyclic aromatic heterocycle featuring a fused naphthalene–pyrimidine ring system with an amino group at the 2-position. The protonated amino group forms a stable crystalline salt with hydrochloric acid, enhancing aqueous solubility and facilitating handling in laboratory applications.Fórmula:C11H9N3•(HCl)xPureza:Min. 95%Cor e Forma:PowderPeso molecular:219.67 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS:1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.Fórmula:C24H24N4O6Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:464.48 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
CAS:<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a new nucleoside analogue that is a phosphoramidite. It has been synthesized as an anticancer agent and antiviral drug. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine has been shown to inhibit the growth of human tumor cells in vitro, suggesting that it may have anticancer activity. This compound also inhibits viral replication by inhibiting DNA synthesis and RNA transcription in infected cells.</p>Fórmula:C41H43N3O9Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:721.79 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine
CAS:<p>N4-Benzoyl-2'-deoxy-2'-fluorocytidine is a novel, synthetic nucleoside that has been shown to inhibit the growth of cancer cells and is being investigated as a potential anticancer drug. N4-Benzoyl-2'-deoxy-2'-fluorocytidine has also been found to be active against HIV, Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), and influenza A virus. It prevents the replication of viruses by inhibiting DNA synthesis in the host cell.</p>Fórmula:C16H16FN3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:349.31 g/molCyclic adenosine 5'-diphosphate ribose ammonium salt
CAS:<p>Cyclic Adenosine 5'-diphosphate ribose ammonium salt (CADPRAM) is a potent inhibitor of cyclic nucleotide phosphodiesterases (PDEs). CADPRAM reversibly inhibits PDEs and prevents the hydrolysis of cAMP. This inhibition can lead to an increase in cytosolic Ca2+. CADPRAM also inhibits polymerase chain reaction, which is why it cannot be used for the treatment of infectious diseases. CADPRAM has been shown to inhibit the activity of enzymes that are known to play a role in clinical pathology, such as adenylate cyclase and phosphodiesterase type 3.</p>Fórmula:C15H21N5O13P2·NH3Pureza:Min. 95%Cor e Forma:White solid.Peso molecular:558.33 g/molBiotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
CAS:Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel, synthetic and highly purified ribonucleoside phosphoramidite. It is used as an activator of nucleic acid synthesis in the preparation of DNA and RNA. Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has been shown to be effective against various types of cancer cells, including leukemic cells and breast cancer cells. The drug also inhibits the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2).Fórmula:C22H35N6O16P3S·xLiPureza:Min. 95%Cor e Forma:PowderPeso molecular:764.53 g/molThymidine-5'-triphosphate trisodium
CAS:<p>Thymidine-5'-triphosphate or dTTP, is a nucleotide used by the cell to synthesize DNA molecules. Thymidine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of thymidine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).</p>Fórmula:C10H17N2O14P3•Na3Pureza:(%) Min. 90%Cor e Forma:White PowderPeso molecular:551.14 g/mol3'-O-Allylguanosine
<p>3'-O-Allylguanosine is a antiviral agent that belongs to the group of synthetic nucleosides. It is a monophosphate analog of guanosine and an activator of ribonucleotide reductase. 3'-O-Allylguanosine has been shown to be effective against cancer cells in vitro. It has also been shown to inhibit DNA synthesis and promote DNA degradation in human leukemia cells, suggesting its potential use for the treatment of leukemia.</p>Fórmula:C13H17N5O5Pureza:Min. 95%Peso molecular:323.3 g/mol5-Bromo-2'-deoxyuridine
CAS:<p>5-Bromo-2'-deoxyuridine (5-BrDU) is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. It is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-BrDU has been shown to induce preconditioning in vivo, reducing neuronal injury after ischemia. This drug also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases such as Alzheimer's disease. 5-BrDU has been shown to inhibit the polymerase chain reaction in wild-type strains of bacteria, but not in strains with a mutation in their DNA gyrase genes.</p>Fórmula:C9H11BrN2O5Pureza:Min. 99 Area-%Cor e Forma:White Off-White PowderPeso molecular:307.1 g/mol2'-Deoxyadenosine-5'-triphosphate disodium salt
CAS:2'-Deoxyadenosine-5'-triphosphate disodium salt is a nucleotide that is formed from adenosine triphosphate (ATP) and deoxyadenosine monophosphate (dAMP). It is an intermediate in the biosynthesis of fatty acids, which are important components of cell membranes. This nucleotide can be used to measure the light exposure of bacteria. 2'-Deoxyadenosine-5'-triphosphate disodium salt has been shown to have antibacterial activity against some Gram-positive bacteria, such as Staphylococcus aureus. The effective dose for these bacteria is 5 µg/mL with a linear model. The biological properties of this nucleotide are still not fully understood, but it is thought to play a role in blood pressure regulation through its effects on fatty acid synthesis.Fórmula:C10H14N5O12P3Na2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:535.15 g/molCoenzyme A sodium salt hydrate
CAS:Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.Fórmula:C21H36N7O16P3SNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:790.53 g/mol5-Aminouridine
CAS:<p>5-Aminouridine is an analog of uridine that is used in the synthesis of RNA. It inhibits the synthesis of RNA by viruses, and it may also inhibit the synthesis of RNA by cells, including muscle cells. 5-Aminouridine has been shown to inhibit protein synthesis in muscle cells incubated with orotic acid. The drug may also interact with other drugs metabolized by UDP-glucose pyrophosphorylase, such as carbamazepine and phenytoin. This interaction may lead to decreased serum levels of these drugs following treatment with 5-aminouridine.</p>Fórmula:C9H13N3O6Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:259.22 g/molN4-Benzoyl-5-methylcytidine
CAS:N4-Benzoyl-5-methylcytidine is a labile chemical that can be uniquely prepared using biochimie. It has been shown to have anticodon activity in assays and is synthesized chemically. The nucleoside is phosphoramidite, which is methylated and reproducible. N4-Benzoyl-5-methylcytidine has been shown to inhibit the growth of cells by blocking the synthesis of purines and pyrimidines. It may also have biophysical properties that are related to its ability to bind to DNA.Fórmula:C17H19N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:361.35 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine is a pesticide that is used as an acaricide, insecticide, and nematicide. It has been shown to be effective in controlling the growth of E. coli and insects by binding to their membranes and inhibiting lipid synthesis. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine binds to the polypeptides in the bacterial cell membrane and inhibits their function, leading to cell death. This drug also has a low toxicity for mammals.</p>Fórmula:C37H35N3O7Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:633.69 g/mol2'-Deoxy-2',2'-difluoro-5-methyluridine
CAS:<p>2'-Deoxy-2',2'-difluoro-5-methyluridine is a synthetic nucleoside analog for use in research</p>Fórmula:C10H12F2N2O5Pureza:Min. 95%Peso molecular:278.21 g/mol2'-O-Methyladenosine 5'-triphosphate lithium - 100 mM aqueous solution
CAS:<p>2'-O-Methyladenosine 5'-triphosphate lithium is a novel nucleotide that has been synthesized to act as an antiviral and anticancer agent. It can be used in the production of ribonucleosides, deoxyribonucleosides, and modified DNA. It is also a high quality phosphoramidite that can be used in the synthesis of DNA and RNA. 2'-O-Methyladenosine 5'-triphosphate lithium has been shown to inhibit the replication of HIV-1 and other viruses by inhibiting viral transcription. It is also active against cancer cells, with an IC50 value of 0.2 μM for HL-60 cells.</p>Fórmula:C11H18N5O13P3•Li3Pureza:Min. 95%Peso molecular:542 g/mol7-Deazaguanosine
CAS:7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.Fórmula:C11H14N4O5Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:282.26 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a connector that is used in optical devices. It is a ligand that binds to the constant region of the antibody, which is part of the molecule that protects against bacteria and viruses. The residue has been shown to have variable conformation in tetrahydrofuran and ethyl group. This molecule can be injected into dimethylformamide with an anion chloride or pyrrolidine ring.</p>Fórmula:C38H37N3O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:647.72 g/mol2′-O-2-Methoxy-2-oxoethyl-5-methyl-cytidine
<p>2′-O-2-Methoxy-2-oxoethyl-5-methylcytidine (2′OMeC) is a synthetic ribonucleoside that is used in DNA synthesis. 2′OMeC is a nucleotide analog that inhibits DNA and RNA synthesis by competitively inhibiting the enzyme activity of DNA polymerase, RNA polymerase, and other enzymes involved in the process. This drug has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). It also has anticancer properties through its ability to inhibit protein synthesis. The novel structure of this drug gives it high quality and purity.</p>Fórmula:C13H19N3O7Pureza:Min. 95%Peso molecular:329.31 g/mol6-Azauridine
CAS:<p>Inhibitor of uridine monophosphate synthase</p>Fórmula:C8H11N3O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:245.19 g/mol2,4-Diamino-6-hydroxy-5-nitrosopyrimidine
CAS:<p>2,4-Diamino-6-hydroxy-5-nitrosopyrimidine is a nucleoside for use in research applications</p>Fórmula:C4H5N5O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:155.12 g/mol2′-O-[2-(Methylamino)-2-oxoethyl]guanosine
CAS:2′-O-[2-(Methylamino)-2-oxoethyl]guanosine is a monophosphate nucleoside with anticancer properties. It has been shown to activate the transcription of genes that regulate cell growth and differentiation, and to induce apoptosis in tumor cells. This compound is an analog of guanosine, which is not modified at the 2′ position. It has been used to synthesize phosphoramidites for oligonucleotide synthesis, and may be useful as a novel therapeutic agent for cancer treatment.Fórmula:C13H18N6O6Pureza:Min. 95%Peso molecular:354.32 g/molUridine 5'-diphosphate disodium salt
CAS:Agonist of P2Y6 purinoceptor; antagonist of P2Y14Fórmula:C9H12N2O12P2Na2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:448.12 g/mol2'-O-Methyladenosine 5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:2'-O-Methyladenosine 5'-triphosphate lithium salt - 100 mM aqueous solution is a modified nucleoside that has antiviral, anticancer, and antimalarial properties. It also has been shown to activate DNA synthesis and inhibit the growth of cancer cells.Fórmula:C11H18N5O13P3·xLiPureza:Min. 95%Cor e Forma:PowderPeso molecular:521.21 g/mol2',3'-Dideoxyadenosine-5'-monothiophosphate
CAS:<p>2',3'-Dideoxyadenosine-5'-monothiophosphate is a nucleoside for use in research applications</p>Fórmula:C10H14N5O4PSPureza:Min. 95%Cor e Forma:Clear liquid.Peso molecular:331.29 g/mol2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt - Aqueous solution
CAS:<p>2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt is a synthetic nucleotide analog of adenosine triphosphate (ATP), modified at the 2'-carbon of the ribose ring. This molecule has potential applications in biochemical, enzymatic, and antiviral research, particularly in studies involving RNA synthesis and viral RNA polymerases.</p>Fórmula:C35H79N9O13P3Pureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:926.98 g/molFludarabine
CAS:<p>Fludarabine is a purine analog and works by interfering with DNA synthesis, which helps to stop the growth of cancer cells.</p>Fórmula:C10H12FN5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.23 g/mol2'-Deoxy-5-hydroxymethyluridine-5'-triphosphate triethylammonium
CAS:2'-Deoxy-5-hydroxymethyluridine-5'-triphosphate triethylammonium salt (dHMUTP) is a noncompetitive inhibitor of transcriptase activity. It inhibits the synthesis of DNA by binding to RNA polymerase on the template strand, thereby blocking the progress of the enzyme along the DNA. This drug has been shown to be effective in inhibiting viral production and growth in mammalian cells, as well as cancer cell culture. Dihydrofolate reductase is required for dHMUTP to function, and it is metabolized in vivo through hydrolysis by glycosylases or antineoplastic properties by nucleotide excision repair enzymes. These enzymes are present in human cells but absent in bacteria and yeast. The drug also has antineoplastic properties due to its ability to inhibit tumor cell proliferation.Fórmula:C10H16N2O15P3·C6H16NPureza:Min. 70 Area-%Cor e Forma:PowderPeso molecular:599.36 g/mol6-Thioguanosine
CAS:<p>6-Thioguanosine is a purine analog that is used in the treatment of skin cancer and bowel disease. It has been shown to be an inhibitor of leukemia cells and also inhibits the growth of colon cancer cells. 6-Thioguanosine binds to the rate constant for uridine phosphorylation, which prevents the production of DNA. This drug also has an anti-inflammatory effect on bowel disease, which may be due to its ability to inhibit bcl-2 protein expression.<br>6-Thioguanosine is a fluorescent derivative that can be used as a substrate for x-ray diffraction data or as a biological sample in biological studies.</p>Fórmula:C10H13N5O4SPureza:Min. 95%Cor e Forma:Slightly Yellow Slightly Green PowderPeso molecular:299.31 g/mol5,6-Dihydro-2'-deoxyuridine
CAS:5,6-Dihydro-2'-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of DNA. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit the activity of catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. The enzyme activities of 5,6-dihydro-2'-deoxyuridine on simplex virus type 1 have been studied in vitro using lymphoblastoid cells. In these studies, the compounds was found to inhibit viral growth and terminate replication. 5,6-Dihydro-2'-deoxyuridine also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1. This drug has also been shown to inhibit amine oxidases in hepFórmula:C9H14N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:230.22 g/mol2'-Deoxy-5-ethynylcytidine
CAS:2'-Deoxy-5-ethynylcytidine is a cytosine analog that inhibits the synthesis of viral DNA and the production of new virus particles. It has been shown to inhibit herpes simplex virus type-1 (HSV-1) in cell cultures, as well as other viruses such as vaccinia and adenovirus. 2'-Deoxy-5-ethynylcytidine has also been shown to have anti-cancer properties in animal studies. This drug binds to the cellular nucleic acid, preventing transcription of viral genes into messenger RNA and preventing protein synthesis, thereby inhibiting replication of the virus. 2'-Deoxy-5-ethynylcytidine also inhibits the synthesis of cellular DNA by binding to nuclear DNA. 2'-Deoxy-5-ethynylcytidine is an analog of cytosine that binds to dna polymerase and prevents it from adding on new nucleotides, which blocks viral reproduction.Fórmula:C11H13N3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:251.24 g/mol2'-Deoxy-5-iodouridine
CAS:2'-Deoxy-5-iodouridine (IDU) is a nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. IDU has been shown to be a potent inhibitor of murine sarcoma virus and human immunodeficiency virus (HIV). IDU also has inhibitory properties on axonal growth, which may be due to its ability to inhibit DNA polymerase II. 2'-Deoxy-5-iodouridine is biocompatible, non-toxic, and can be used in high concentrations without any acute toxicities.Fórmula:C9H11IN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:354.1 g/mol2'-Deoxy-8-oxo-adenosine
CAS:<p>2'-Deoxy-8-oxo-adenosine is a nucleoside that is a hydrogen bond donor. It is an analogue of adenosine, and has been shown to inhibit the growth of breast cancer cells. 2'-Deoxy-8-oxo-adenosine reacts with the enzyme dATP pyrophosphohydrolase to form 8-oxo-2'-deoxyadenosine, which inhibits mitochondrial DNA synthesis by preventing the incorporation of inorganic phosphate into mitochondrial DNA. This process leads to reduced ATP production, leading to cell death. The reactive properties of 2'-Deoxy-8-oxo-adenosine make it suitable for use as a probe molecule in chemical biology, as well as in biochemical studies on human serum.</p>Fórmula:C10H13N5O4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:267.25 g/mol8-Thioguanosine
CAS:<p>8-Thioguanosine is a purine derivative with reactive chlorine atoms. It has been shown to be a potent inhibitor of cellular targets, including monoclonal antibodies, growth factors, and transcription-polymerase chain reactions (PCR). 8-Thioguanosine binds to the antibody response by modulating the function of the B cells. This drug also has immunomodulatory effects that have been shown in animal models. 8-Thioguanosine is used as an immunosuppressant in patients undergoing bone marrow transplants and solid organ transplants.</p>Fórmula:C10H13N5O5SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:315.3 g/mol2',3'-Dideoxy-3'-fluorouridine
CAS:<p>2',3'-Dideoxy-3'-fluorouridine is a synthetic analog of uridine with chemical modifications that disrupt RNA and DNA synthesis. Because of this, it’s often studied or used as an antiviral or anticancer agent.</p>Fórmula:C9H11FN2O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:230.2 g/molRibavirin 5'-monophosphate dilithium
CAS:<p>Ribavirin is a synthetic nucleoside analog that is used as an antiviral agent. Ribavirin 5'-monophosphate dilithium (RPM) is a high-quality, novel phosphoramidite monophosphate of ribavirin. It has antiviral activity against herpesviruses, adenoviruses, and poxviruses. The antiviral properties of RPM are due to its ability to inhibit viral RNA synthesis through inhibition of the viral enzyme ribonucleotide reductase. RPM is also active against DNA viruses such as human papilloma virus and Epstein-Barr virus.</p>Fórmula:C8H11Li2N4O8PPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:336.05 g/mol3'-Deoxyadenosine
CAS:<p>3'-Deoxyadenosine is a nucleoside that is an inhibitor of adenylate cyclase. It has been shown to inhibit the growth of mouse tumor cells and induce apoptosis in HL-60 cells. 3'-Deoxyadenosine inhibits the production of pro-apoptotic protein, which may be due to its ability to activate toll-like receptor 4. 3'-Deoxyadenosine also has strong anti-inflammatory properties and can be used for the treatment of infectious diseases caused by bacteria, such as Mycobacterium tuberculosis or Streptococcus pyogenes. 3'-Deoxyadenosine binds to DNA polymerases and inhibits the replication of DNA by blocking the incorporation of deoxynucleotides into DNA. This compound has been shown to have thermodynamic data consistent with a stable secondary structure at high temperatures.br></p>Fórmula:C10H13N5O3Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:251.25 g/mol
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