Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
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Pseudouridine
CAS:Uridine isomer; found in tRNAFórmula:C9H12N2O6Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:244.2 g/molCytidine
CAS:Cytidine is a nucleoside that belongs to the group of pyrimidine nucleosides. It can be absorbed from the intestine and hydrolyzed to uridine by intestinal enzymes. Cytidine has been shown to inhibit angiogenesis in animal model systems and transfection experiments, as well as being genotoxic in vitro. Cytidine has also been shown to inhibit polymerase chain reactions (PCR) and enzyme activities, such as cytidine deaminase, which converts cytidine into uracil.
Fórmula:C9H13N3O5Pureza:Min. 99 Area-%Cor e Forma:White Off-White PowderPeso molecular:243.22 g/molO6-Methylguanosine
CAS:Intermediate in the synthesis of nelarabineFórmula:C11H15N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:297.27 g/molN4,N4,2’-O-Trimethylcytidine
CAS:N4,N4,2’-O-Trimethylcytidine is a novel nucleoside that has been shown to be an anticancer drug. It inhibits the growth of cells by selectively inhibiting their DNA synthesis. N4,N4,2’-O-Trimethylcytidine is also active against viruses and is able to inhibit viral replication by blocking the synthesis of deoxyribonucleosides and phosphoramidites. This compound has been synthesized in high purity and quality with CAS No. 34218-81-0.Fórmula:C12H19N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.3 g/molN2,N2-Dimethylguanosine
CAS:N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.Fórmula:C12H17N5O5Pureza:Min. 98 Area-%Cor e Forma:Off-White PowderPeso molecular:311.3 g/mol5-Bromo-2'-deoxy-5'-O-DMT-uridine
5-Bromo-2'-deoxy-5'-O-DMT-uridine is an antiviral nucleoside that is a monophosphate analog of deoxyuridine. 5-Bromo-2'-deoxy-5'-O-DMT-uridine can be used to treat patients with leukemia and other cancers. 5-Bromo-2'-deoxy-5'-O-DMT-uridine has been shown to induce tumor cell apoptosis in vitro and in vivo, as well as inhibit the proliferation of tumor cells by blocking the synthesis of DNA. This drug also has anticancer properties, which are due to its ability to block RNA synthesis.Fórmula:C30H29BrN2O7Pureza:Min. 95%Cor e Forma:Off-white to beige solid.Peso molecular:609.48 g/mol2'-Deoxy-N4-methylcytidine
CAS:2'-Deoxy-N4-methylcytidine is a modified nucleoside that is used to inhibit the activity of protein kinases. It has been shown to inhibit the function of two different types of enzymes, eukaryotic protein kinase and bacterial RNA polymerase. 2'-Deoxy-N4-methylcytidine inhibits the activity of these enzymes by modifying their structure, which in turn prevents them from carrying out their normal functions. This modification can be achieved through deamination or protonation reactions with this drug. The effects of this drug are nonparametric and are observed at transcript levels.Fórmula:C10H15N3O4Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:241.24 g/mol2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine
CAS:2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine is a synthetic nucleoside that has the ability to activate and inhibit the growth of cancer cells. This compound is a phosphoramidite, and it has been modified by the addition of an isobutyrate group at the 2' position. The structure of this nucleoside is similar to that of natural guanosine, but with an additional 2' oxygen atom. This modification can be used for inhibition of DNA synthesis in cells and may have antiviral effects.Fórmula:C35H37N5O7Pureza:Min. 97 Area-%Peso molecular:639.71 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorocytidine
CAS:Used as an intermediate for the preparation of modified oligonucleotides and other cytidine derivatives containing a 2',2'-difluoro modification.Fórmula:C23H19F2N3O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:471.42 g/mol2'-Deoxyadenosine-5'-triphosphate trisodium
CAS:2'-Deoxyadenosine-5'-triphosphate or dATP, is a nucleotide used by cells to synthesize DNA molecules. 2'-Deoxyadenosine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of 2'-deoxyadenosine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).Fórmula:C10H13N5O12P3·3NaPureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:557.13 g/mol2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution
2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution is a synthetic nucleoside that can be used as an antiviral and anticancer agent. The drug inhibits viral replication by inhibiting the synthesis of DNA. The drug also suppresses tumor growth by inhibiting the production of RNA and DNA in cancer cells.Fórmula:C10H18N3O14P3•NaxPureza:Min. 90 Area-%Cor e Forma:Clear LiquidPeso molecular:497.18 g/mol2',3'-Dideoxy-3'-fluoroguanosine
CAS:2',3'-Dideoxy-3'-fluoroguanosine is a synthetic nucleoside analog based on guanosine. It is structurally altered to interfere with DNA or RNA synthesis, making it potentially useful as an antiviral or anticancer agent.Fórmula:C10H12FN5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:269.24 g/mol5-Formyl-2'-O-methylcytidine
CAS:5-Formyl-2'-O-methylcytidine is a molecule that is involved in cellular processes such as DNA methylation, the addition of a methyl group to the 5 position of a cytosine residue. It has been shown to be an important epigenetic regulator and can be used as a strategy to treat tuberculosis. 5-Formyl-2'-O-methylcytidine is synthesized from guanine, which undergoes conversion into cytosine via enzymatic modification. This process is catalyzed by methyltransferase enzymes and it is usually carried out with S-adenosylmethionine (SAM) as the methyl donor. The product then converts back into guanine through deamination, which can be catalyzed by either adenine phosphoribosyltransferase or adenylate kinase.Fórmula:C11H15N3O6Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:285.25 g/mol5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
CAS:5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It has been shown to be a novel, high purity, and CAS No. 251647-50-4. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.Fórmula:C38H43N5O9Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:713.78 g/moldNTP pre-mixes, 25mM aqueous solution
CAS:dATP, dTTP, dCTP and dGTP pre-mixed in a single vial
Pureza:Min. 95%2'-Deoxy-5-methylcytidine-5'-monophosphate disodium
CAS:2'-Deoxy-5-methylcytidine-5'-monophosphate disodium (2D5MCP) is a nucleoside analog that inhibits the synthesis of DNA. It is used in the treatment of cervical cancer and other cancers that are dependent on DNA synthesis. 2D5MCP works by binding to and inhibiting the activity of an enzyme called DNA polymerase, which is needed for DNA replication. This drug also has been shown to inhibit fatty acid synthase enzymes and surface glycoprotein enzymes, which may be responsible for its anti-cancer effects. 2D5MCP has been shown to have an effective dose range between 50 and 150 mg/kg, with no significant side effects seen at doses up to 300 mg/kg. 2D5MCP does not bind to plasma proteins or erythrocytes, so it can be administered intravenously without risk of tissue damage caused by osmotic lysis.Fórmula:C10H14N3O7PNa2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:365.19 g/mol2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium
CAS:2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium (2'DFUR) is a fatty acid that is resistant to many antibacterial agents. 2'DFUR inhibits the biosynthesis of bacterial cell walls, leading to cell death. This drug has been shown to have potent antibacterial activity against Staphylococcus strains and other bacteria. The mechanism of action is not yet fully understood, but it may involve inhibition of nucleotidyltransferase and aminopropyl transferase enzymes.Fórmula:C9H11FN2O14P3Li4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:510.87 g/mol5'-Deoxy-5'-iodothymidine
CAS:5'-Deoxy-5'-iodothymidine is an antiviral nucleoside that inhibits viral replication by competing with the natural substrate, deoxyribonucleotide triphosphate, for incorporation in DNA. 5'-Deoxy-5'-iodothymidine has been shown to be a novel antiviral agent and an activator of host immune responses against virus infections. 5'-Deoxy-5'-iodothymidine is also used as an intermediate for the synthesis of phosphoramidites, which are used in the production of DNA.Fórmula:C10H13IN2O4Pureza:Min. 95%Peso molecular:352.13 g/mol2'-Deoxyadenosine-3'-monophosphate sodium salt
CAS:2'-Deoxyadenosine-3'-monophosphate sodium salt (dAMP) is a novel nucleoside analog that is the sodium salt of 2'-deoxyadenosine-3'-monophosphate. It has shown anticancer and antiviral activity in vitro, as well as cytotoxicity against some human cancer cell lines. It has also been shown to be active against HIV-1 and herpes simplex virus type 1. The drug is modified with an amino group at the 2' position of the ribose sugar, which increases its stability in vivo and reduces its toxicity. This product also contains high purity, high quality, and novel deoxyribonucleosides that are synthesized by a phosphoramidite method.Fórmula:C10H14N5O6P·2NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:377.2 g/mol1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil
CAS:1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil is a nucleoside analog for research applications. It contains a β-D-arabinofuranose sugar and the fluorine (F) substitution at the 2'-position enhances stability and improves resistance to enzymatic degradation. The 5-methyluracil base makes it structurally similar to thymidine, allowing it to be recognized by DNA polymerases and kinases.Fórmula:C10H13FN2O5Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:260.22 g/mol
