Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2638 produtos de "Nucleotídeos"
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7-Deaza 2-C-methyl-N6-methyladenosine
CAS:7-Deaza 2-C-methyl-N6-methyladenosine is a nucleoside that is modified with a methyl group at the 7 position of the deoxyribose ring. It has antiviral and anticancer properties. 7-Deaza 2-C-methyl-N6-methyladenosine is an activator of phosphoramidites, which are compounds that can be used to synthesize DNA or RNA.Fórmula:C13H18N4O4Pureza:Min. 95 Area-%Peso molecular:294.31 g/mol8-Bromoadenosine
CAS:8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells. The drug may be useful for the treatment of leukemia or obesity-related diseases such as diabetes mellitus type 2.
Fórmula:C10H12BrN5O4Pureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:346.14 g/mol4-Amino-1-(2-deoxy-α-D-erythro-pentofuranosyl)-5-methyl-2(1H)-pyrimidinone
CAS:4-Amino-1-(2-deoxy-α-D-erythro-pentofuranosyl)-5-methyl-2(1H)-pyrimidinone is a novel phosphate derivative of ribonucleosides, including 2'-deoxyadenosine and 2'-deoxycytidine. 4ADP has antiviral and anticancer activities, and can be used as a substrate for the synthesis of phosphoramidites. These derivatives are modified by the introduction of substituents at the 5' position of the pentose sugar. The monophosphate form is synthesized by reacting with sodium hydroxide followed by hydrolysis with dilute acid. The diphosphate form is synthesized by reacting with phosphorus oxychloride in presence of pyridine.Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.24 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine
CAS:2'-O-(2-methoxyethyl)-5-methylcytidine is a novel antiviral monophosphate nucleoside that has been shown to be a potent activator of the immune system. It was synthesized by modifying a deoxyribonucleoside and phosphoramidite. 2'-O-(2-methoxyethyl)-5-methylcytidine is synthetic and can be used as an anticancer drug for the treatment of leukemia, lymphoma, and other cancers. This compound has also shown efficacy in treating diphosphate nucleotides such as HIV-1 reverse transcriptase, which is an enzyme crucial for viral replication.Fórmula:C13H21N3O6Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:315.32 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS:Used as a protected guanosine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group acts as a bulky and selectively acid-labile protecting group for the 3' and 5' hydroxyl groups of the guanosine ribonucleoside during RNA oligonucleotide synthesis.Fórmula:C22H39N5O6Si2Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:525.76 g/mol2',5'-Dideoxyadenosine
CAS:2',5'-Dideoxyadenosine is a nucleotide analog that inhibits the enzyme adenylate cyclase, by binding non-competitively via the P-site
Fórmula:C10H13N5O2Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:235.25 g/moltrans-Zeatin riboside
CAS:Trans-zeatin riboside is a cytokinin that is structurally related to adenosine. It has been shown to inhibit the adenosine a3 receptor, which decreases the production of reactive oxygen species in human serum and enhances the uptake of glucose. Trans-zeatin riboside also inhibits nuclear DNA fragmentation and increases water permeability in plant tissues. This chemical has been shown to stimulate photosynthetic activity in plants at an optimum concentration of 10 μg/ml. Trans-zeatin riboside should be stored at -20 degrees Celsius for long-term storage.Fórmula:C15H21N5O5Cor e Forma:White Off-White PowderPeso molecular:351.36 g/mol4-Thiouridine-5'-triphosphate sodium salt - aqueous solution
CAS:4-Thiouridine-5'-triphosphate sodium salt - aqueous solution (4TUTP) is an analog of uridine and can be used as a template for the synthesis of single-stranded DNA. 4TUTP has been shown to have a high affinity for dsDNA, allowing it to form a ternary complex with DNA polymerase and single-stranded DNA template. 4TUTP can also be used to prepare samples for profiling experiments or other molecular studies. It is reactive, so should be handled with caution in order to avoid unwanted crosslinking. 4TUTP may also be used in chloroplast research.Fórmula:C9H15N2O14P3S·xNaPureza:Min. 95 Area-%Cor e Forma:Clear LiquidPeso molecular:500.20 g/molCoenzyme A trilithium salt
CAS:Coenzyme A trilithium salt is a synthetic cofactor that is used in the synthesis of long-chain fatty acids. It is membrane permeable and has minimal toxicity, making it an attractive candidate for treating hepatic steatosis. Coenzyme A trilithium salt also activates human mitochondrial beta-oxidation by increasing the availability of substrate and enhancing the expression of genes involved in beta-oxidation. This molecule has been shown to be effective in improving the symptoms of X-linked adrenoleukodystrophy (X-ALD) by stimulating creatine kinase activity and suppressing lysosomal accumulation of long chain fatty acids.
Fórmula:C21H33Li3N7O16P3SPureza:Min. 80%Cor e Forma:White Off-White PowderPeso molecular:785.33 g/mol5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine
CAS:5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.Fórmula:C36H39N5O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:669.74 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine
CAS:This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucleFórmula:C31H31FN2O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:562.59 g/molGuanosine-5'-[(b,gamma)-imido]triphosphate sodium salt
CAS:Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is a novel antiviral agent that has been shown to inhibit the replication of human adenovirus type 5 (AdV-5) and herpes simplex virus type 1 (HSV-1). It is phosphorylated by adenylate kinase to guanosine diphosphate. Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is an activator for DNA polymerase alpha and DNA topoisomerase I. It also inhibits the proliferation of tumor cells in culture.Fórmula:C10H17N6O13P3·xNaPureza:Min. 95%Cor e Forma:White PowderPeso molecular:522.2 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS:2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applicationsFórmula:C15H20ClN5O4H2OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:378.81 g/mol5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine
CAS:5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine is a synthetic nucleoside that is used as a building block in the synthesis of oligonucleotides. This chemical has an electronegativity value of 1.7, which means that it is more electronegative than guanine (1.0). It also has a conjugated system and is stable under a range of conditions. 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine reacts with tetrazole in the presence of phosphoramidite, yielding the corresponding 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-N-isobutyrylguanosine, which can then be used toFórmula:C35H37N5O7Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:639.71 g/mol4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS:4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Fórmula:C5H5N5OPureza:Min. 95%Peso molecular:151.13 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activitiesFórmula:C35H34FN2O10•C6H16NPureza:Min. 95%Peso molecular:763.87 g/mol6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine
CAS:6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.Fórmula:C11H12ClN3O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.69 g/mol8-Chloro-2'-deoxyguanosine
CAS:8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.Fórmula:C10H12ClN5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:301.69 g/mol6-Azacytidine
CAS:6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.Fórmula:C8H12N4O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:244.2 g/mol5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine
CAS:5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.Fórmula:C13H14ClN5O5Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:355.74 g/mol
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