Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2638 produtos de "Nucleotídeos"
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Guanosine 3',5'-cyclic monophosphate sodium salt
CAS:Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP) is a cyclic nucleotide that is involved in the regulation of many cellular processes. It binds to specific guanine nucleotide-binding proteins (G proteins) and activates protein kinase A, which regulates glucose metabolism and energy production. cGMP also affects neuronal death, axonal growth, and bowel disease by acting as a cyclase inhibitor or activating the immune system. It has been shown to reduce the severity of infectious diseases such as HIV and malaria by activating the immune system.Fórmula:C10H11N5NaO7PPureza:Min. 95%Cor e Forma:PowderPeso molecular:367.19 g/mol5'-O-Tritylthymidine
CAS:5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Fórmula:C29H28N2O5Pureza:Min. 95%Peso molecular:484.54 g/mol9-Deazaguanosine
CAS:9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.
Fórmula:C11H14N4O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:282.25 g/mol2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine
CAS:2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine is a modified nucleoside analog for research applicationsFórmula:C14H18FN5O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:355.33 g/molPalmitoyl coenzyme A potassium salt
CAS:Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.Fórmula:C37H65N7O17P3SKPureza:Min. 95%Cor e Forma:White PowderPeso molecular:1,044.03 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine
CAS:2'-O-(2-Methoxyethyl)-5-methyluridine is a uridine nucleoside that has been prepared by the reaction of amidite with 5-methyluridine. 2'-O-(2-Methoxyethyl)-5-methyluridine is an important intermediate in the synthesis of oligonucleotides, which are synthesized from phosphoramidites. The phenyl group on the amido group is a reactive group that reacts with other functional groups to form an oligonucleotide. 2'-O-(2-Methoxyethyl)-5-methyluridine has a high yield and can be used as a reagent for organic chemistry.Fórmula:C13H20N2O7Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:316.31 g/mol2,6-Dichloro-9-(β-D-ribofuranosyl)purine
CAS:2,6-Dichloro-9-(β-D-ribofuranosyl)purine is a nucleoside analog composed of a modified purine base and a ribose sugar. It has possible applications as an intermediate in nucleoside chemistry, particularly for the synthesis of functionalized purine nucleosides used in biological and pharmaceutical research.Fórmula:C10H10Cl2N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:321.12 g/mol8-Aza-6-hydroxy-2-mercaptopurine
CAS:8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.Fórmula:C4H3N5OSPureza:Min. 95%Cor e Forma:PowderPeso molecular:169.17 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.
Fórmula:C32H32FN3O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:589.61 g/molCytidine 5'-monophosphate disodium salt
CAS:Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.Fórmula:C9H12N3Na2O8PPureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:367.16 g/molGuanosine 5'-O-(2-thiodiphosphate) trilithium salt
CAS:Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.Fórmula:C10H12Li3N5O10P2SPureza:Min. 85 Area-%Cor e Forma:PowderPeso molecular:477.06 g/mol5-Methoxycarbonylmethyl-2-thiouridine
CAS:Nucleoside functionalised on the baseFórmula:C12H16N2O7SPureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:332.33 g/mol8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
CAS:8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt (8-CPT-cAMP) is a cyclic nucleotide that activates adenyl cyclase, which increases intracellular levels of the second messenger cAMP. It also inhibits P2Y receptors and other ion channels. 8-CPT-cAMP has been shown to be effective in activating cells expressing the enzyme camp levels, such as those found in heart muscle cells. This drug is used clinically to lower blood pressure, as it has been shown to activate amp-activated protein kinase and calcium chelator. 8-CPT-cAMP may have clinical applications for the treatment of cancer due to its ability to induce cell cycle arrest and apoptosis.Fórmula:C17H16ClN5O6PS·NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:507.82 g/mol(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
CAS:(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposesFórmula:C19H21N5O4Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:383.4 g/mol5-(Cyanomethyl)-uridine
CAS:5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.Fórmula:C11H13N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.24 g/mol5-Fluorocytosine
CAS:Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.Fórmula:C4H4FN3OPureza:Min. 95%Cor e Forma:White PowderPeso molecular:129.09 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monophFórmula:C38H34N8O5Pureza:Min. 95%Peso molecular:682.73 g/mol7-Deaza-2'-deoxy-6-methoxyguanosine
CAS:7-Deaza-2'-deoxy-6-methoxyguanosine is a modified nucleoside and antiviral agent. It has been shown to inhibit the synthesis of DNA, RNA and protein in cells infected with the herpes simplex virus (HSV). 7-Deaza-2'-deoxy-6-methoxyguanosine is also an anticancer agent that has been shown to inhibit tumor growth in animal models. This compound is synthesized by phosphoramidite chemistry and is a novel precursor for the preparation of modified DNA and RNA. The purity of this product is greater than 98%.Fórmula:C12H16N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:280.29 g/mol2',3',5'-Tri-O-acetyl-6-azauridine
CAS:2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.
Fórmula:C14H17N3O9Pureza:Min. 95%Cor e Forma:PowderPeso molecular:371.3 g/mol3,5-Dichloro-4-pyridone-1-acetic acid
CAS:3,5-Dichloro-4-pyridone-1-acetic acid is a chlorinated derivative of 7-aminocephalosporanic acid that is synthesized from hydrochloric acid and chloroacetic anhydride. It is used in the pharmaceutical industry as a reagent to produce medicines such as antibiotics and anti-inflammatory agents. The product yield of this reaction is high, which makes it an excellent choice for industrial use. 3,5-Dichloro-4-pyridone-1-acetic acid also has a low toxicity profile and can be easily degraded by bacteria in the environment.Fórmula:C7H5Cl2NO3Pureza:Min. 95%Peso molecular:222.02 g/mol
