Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Foram encontrados 191 produtos para "Sistema complementar".
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Vilobelimab
CAS:Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.Pureza:99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.86 kDa (Predicted)Sutimlimab
CAS:Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:144.8 kDa (Predicted)Vesencumab
CAS:Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.Pureza:99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.22 kDa (Predicted)Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46Tesidolumab
CAS:Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Pureza:99.72% (SEC-HPLC) - > 95%Cor e Forma:Transparent LiquidPeso molecular:144.16 kDa (Predicted)Avdoralimab
CAS:Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).Pureza:>95%Cor e Forma:Transparent LiquidPeso molecular:145.9 kDa (Predicted)PMX 205 acetate
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Fórmula:C47H66N10O8Pureza:99.4%Cor e Forma:SolidPeso molecular:899.09Lampalizumab
CAS:Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.Pureza:>95%Cor e Forma:LiquidPeso molecular:143.8 kDa (Predicted)Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Fórmula:C62H111N11O12Pureza:99.00% - 99.94%Cor e Forma:White SolidPeso molecular:1202.61SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Fórmula:C24H29F3N4O6Pureza:98.93% - 99.98%Cor e Forma:White SolidPeso molecular:526.5055Ravulizumab
CAS:Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:145.80 kDa (Predicted)JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Fórmula:C49H63FN10O9Cor e Forma:SolidPeso molecular:955.0845Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Fórmula:C68H100F3N23O19S2Cor e Forma:SolidPeso molecular:1664.79PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Cor e Forma:SolidPeso molecular:896.09AMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Fórmula:C83H117N23O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1789.11TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Fórmula:C107H170N40O26Pureza:98%Cor e Forma:SolidPeso molecular:2432.75Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Fórmula:(C2H4O)nC170H248N50O47S4·xC2H4O2Pureza:97.10%Cor e Forma:Odour SolidPeso molecular:1501.7ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Cor e Forma:SolidPeso molecular:120702.76Factor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Fórmula:C19H16N4O2Cor e Forma:SolidPeso molecular:332.3559PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:Solid
