Derivados de Purinas e Pirimidinas
As purinas possuem uma estrutura bicíclica, formada por um anel de seis membros fundido a um anel de cinco membros, ambos contendo átomos de nitrogênio em posições-chave. Os derivados das purinas, como a adenina e a guanina, são essenciais para a formação do DNA e RNA. Estes compostos possuem aplicações terapêuticas no tratamento do câncer e de doenças virais, pois inibem a replicação celular. As pirimidinas, por outro lado, possuem uma estrutura monocíclica de seis membros com dois átomos de nitrogênio. Seus derivados, como citosina, timina e uracila, também são componentes essenciais do DNA e RNA e são utilizados na quimioterapia e em tratamentos antivirais.
Na CymitQuimica, oferecemos derivados de purinas e pirimidinas para pesquisa em biologia molecular, genômica e desenvolvimento de terapias inovadoras.
Foram encontrados 8888 produtos de "Derivados de Purinas e Pirimidinas"
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2-(2-Chlorophenyl)pyrimidine-5-carboxylic acid
CAS:Fórmula:C11H7ClN2O2Pureza:95.0%Peso molecular:234.64(R)-Roscovitine
CAS:<p>M02443 - (R)-Roscovitine</p>Fórmula:C19H26N6OPureza:>95%Cor e Forma:SolidPeso molecular:354.458(6-Ethoxy-pyrimidin-4-yl)-methyl-piperidin-3-yl-amine hydrochloride
CAS:Fórmula:C12H21ClN4OPureza:95.0%Peso molecular:272.785-methyl-4-(piperazin-1-yl)pyrimidine
CAS:Fórmula:C9H14N4Pureza:95.0%Cor e Forma:SolidPeso molecular:178.239(5-cyano-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid
CAS:Fórmula:C7H5N3O4Pureza:95.0%Peso molecular:195.1344-(ISOBUTYLAMINO)-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLIC ACID
CAS:Fórmula:C10H15N3O2SPureza:95.0%Peso molecular:241.314,6-Dichloro-2-methoxypyrimidine
CAS:Fórmula:C5H4Cl2N2OPureza:95%Cor e Forma:White to light yellow powderPeso molecular:179N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride
CAS:Fórmula:C19H23ClN6O4Pureza:97%Peso molecular:434.88ETHYL 6-CHLORO-5-METHYLPYRIMIDINE-4-CARBOXYLATE
CAS:Fórmula:C8H9ClN2O2Pureza:97%Peso molecular:200.622-Hydrazino-4-methoxypyrimidine
CAS:Fórmula:C5H8N4OPureza:95%Cor e Forma:FlakesPeso molecular:140.1462-(2-aminoethyl)-6-methyl-4-pyrimidinol dihydrochloride
CAS:Fórmula:C7H13Cl2N3OPureza:95.0%Cor e Forma:SolidPeso molecular:226.14-Amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
CAS:Fórmula:C8H10FN3O3SPureza:95%Cor e Forma:SolidPeso molecular:247.244,6-Dimethoxypyrimidine-2-carbonitrile
CAS:Fórmula:C7H7N3O2Pureza:95.0%Cor e Forma:SolidPeso molecular:165.1521-(3-Nitrophenyl)-3-(piperidin-4-yl)ureahydrochloride
CAS:Fórmula:C12H17ClN4O3Pureza:95.0%Peso molecular:300.741-Isobutyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea
CAS:Pureza:98%Peso molecular:318.22000125-Chloropyrimidine-2-carboxylic acid
CAS:Fórmula:C5H3ClN2O2Pureza:95.0%Cor e Forma:Solid, White powderPeso molecular:158.54METHYL 2-(3-(2-METHOXYBENZYL)UREIDO)BENZOATE
CAS:Fórmula:C17H18N2O4Pureza:95.0%Peso molecular:314.3414-chloro-5,6-dimethyl-2-pyrrolidin-1-ylpyrimidine
CAS:Fórmula:C10H14ClN3Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:211.696-Methyl-2-trifluoromethylpyrimidin-4-ol
CAS:Fórmula:C6H5F3N2OPureza:95.0%Cor e Forma:SolidPeso molecular:178.1141-(2-Bromophenyl)-3-(piperidin-4-yl)ureahydrochloride
CAS:Fórmula:C12H17BrClN3OPureza:95.0%Peso molecular:334.64N-(2,4-DIMETHOXYBENZYL)-5-FLUOROPYRIMIDIN-2-AMINE
CAS:Fórmula:C13H14FN3O2Pureza:95%Peso molecular:263.272(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol
CAS:Fórmula:C13H19N5O5Pureza:98%Cor e Forma:SolidPeso molecular:325.325[1-(6-Cyclopropylamino-pyrimidin-4-yl)-piperidin-3-yl]-carbamic acid tert-butyl ester
CAS:Fórmula:C17H27N5O2Pureza:95%Peso molecular:333.4364-chloro-5-ethyl-2-methylpyrimidine
CAS:Fórmula:C7H9ClN2Pureza:95.0%Cor e Forma:LiquidPeso molecular:156.612,4-Dichloro-6-methyl-5-nitropyrimidine
CAS:Fórmula:C5H3Cl2N3O2Pureza:98%Cor e Forma:Solid, PowderPeso molecular:2081-(2-(Methylthio)pyrimidin-4-yl)ethanone
CAS:Fórmula:C7H8N2OSPureza:97%Cor e Forma:SolidPeso molecular:168.21N-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]-N’-pyridin-3-ylurea
Fórmula:C13H11F3N4OPeso molecular:296.2534-[(1R,2R)-2-Benzyloxy-1-methyl-propoxy]-2-chloro-5-(trifluoromethyl)pyrimidine
CAS:Pureza:98%Peso molecular:360.76000984-[6-(3-Trifluoromethyl-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Fórmula:C16H11F3N4Pureza:95.0%Peso molecular:316.287Tenofovir Dimer Triethylammonium Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Tenofovir Dimer is a dimer of Tenofovir (T018500). Tenofovir is a reverse transcriptase inhibitor. Used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Fórmula:C30H56N12O7P2Cor e Forma:NeatPeso molecular:758.79Lestaurtinib
CAS:Produto Controlado<p>Stability Photosensitive<br>Applications It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML).<br></p>Fórmula:C26H21N3O4Cor e Forma:NeatPeso molecular:439.46Methotrexate-d3 Pentaglutamate Trifluoroacetate (>90%)
CAS:Produto Controlado<p>Applications Methotrexate-d3 Pentaglutamate is the isotope labelled analog of Methotrexate Pentaglutamate (M260735); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C40H47D3N12O17(C2HF3O2)xCor e Forma:NeatPeso molecular:973.91Febuxostat Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.<br>References Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C22H24N2O9SCor e Forma:Off White PowderPeso molecular:492.505-Amino-4-pyrazolecarboxamide
CAS:Produto ControladoFórmula:C4H6N4OCor e Forma:Off White To Light BrownPeso molecular:126.1174-Hydroxy-1,3-benzenedicarbonitrile
CAS:Produto Controlado<p>Applications 4-Hydroxy-1,3-benzenedicarbonitrile is used in the preparation of febuxostat (F229000), a non-purine xanthine oxidase inhibitor used as a treatment for hyperuricaemia and chronic gout.<br>References Smith, C.J., et al.: Bioorg. Med. Chem. Lett., 20, 346 (2010); Cramp. S., et al.: BIoorg. Med. Chem. Lett., 20, 2516 (2010); Sato, T., et al.: Bioorg. Med. Chem. Lett., 19, 184 (2009);<br></p>Fórmula:C8H4N2OCor e Forma:NeatPeso molecular:144.13(S)-9-[2-(Hydroxypropyl] Adenine
CAS:<p>Applications (S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506).<br>References Roux, L. et al.: Eur. J. Med. Chem., 63, 869 (2013); Schaeffer, H. et al.: J. Med. Chem., 15, 456 (1972); Schaeffer, H. & Vince, R.: J. Med. Chem., 10, 689 (1967)<br></p>Fórmula:C8H11N5OCor e Forma:Off White SolidPeso molecular:193.206Regadenoson-d3
CAS:Produto Controlado<p>Applications A selective A2A adenosine receptor agonist in myocardial imaging.<br>References Palle, V.P., et al.: J. A. Drug Dev. Res., 50, 64 (2000), Gordi, T., et al.: J. Clin. Pharmacol., 47, 825 (2007), Zhao, G., et al.: J. Cardiovas. Pharmacol., 52, 467 (2008), Botvinick, E., et al.: J. Nuc. Med. Technol., 37, 14 (2009),<br></p>Fórmula:C15H15D3N8O5Cor e Forma:NeatPeso molecular:393.371-Methyl-1,4-dihydronicotinamide
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 1-Methyl-1,4-dihydronicotinamide (cas# 17750-23-1) is a compound useful in organic synthesis.<br></p>Fórmula:C7H10N2OCor e Forma:NeatPeso molecular:138.172-Pyrimidinemethanamine
CAS:Produto Controlado<p>Applications 2-Pyrimidinemethanamine (cas# 75985-45-4) is a useful research chemical.<br></p>Fórmula:C5H7N3Cor e Forma:NeatPeso molecular:109.13Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C20H33N6O9PCor e Forma:NeatPeso molecular:532.48(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole
CAS:Produto ControladoFórmula:C14H18N2Cor e Forma:NeatPeso molecular:214.31Benzofuran-6-carboxylic Acid
CAS:Produto Controlado<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Fórmula:C9H6O3Cor e Forma:NeatPeso molecular:162.14Caffeine Citrate
CAS:<p>Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);<br></p>Fórmula:C8H10N4O2·C6H8O7Cor e Forma:WhitePeso molecular:386.311,11b-Dedihydrotetrabenazine
CAS:Produto Controlado<p>Applications 1,11b-Dedihydrotetrabenazine is a product of photolytic degradation of Tetrabenazine (T284000) which is a dopamine depleting agent.<br>References Bourezg, Z., et al.: J. Pharmaceut. Biomed., 91, 138 (2014); Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966); Janovic, J., et al.: Ann. Neurol., 11, 41 (1982); Janovic, J., et al.: Neurology, 38, 391 (1988);<br></p>Fórmula:C19H25NO3Cor e Forma:NeatPeso molecular:315.41N-Sulfamoylethyl Naratriptan Pyridinium Chloride
CAS:Produto Controlado<p>Impurity Naratriptan Impurity F<br>Stability Hygroscopic<br>Applications 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium Chloride is an impurity of Naratriptan (N378730).<br></p>Fórmula:C20H27ClN4O4S2Cor e Forma:NeatPeso molecular:487.04Methotrexate Hexaglutamate Trifluoroacetate
CAS:<p>Stability Hygroscopic<br>Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C45H57N13O20·x(C2HF3O2)Cor e Forma:Yellow SolidPeso molecular:1214.03cis (2,3)-Dihydro Tetrabenazine
CAS:Produto Controlado<p>Applications A metabolite of Tetrabenazine in vivo, which is likely the active pharmacological agent. The cis isomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.<br>References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),<br></p>Fórmula:C19H29NO3Cor e Forma:NeatPeso molecular:319.445-Carboxy-2'-deoxyuridine
CAS:Produto Controlado<p>Applications 5-Carboxy-2'-deoxyuridine, is a derivative of Trifluridine, an anti-herpesvirus antiviral drug, used primarily on the eye.<br>References Kuster, P., et al.: CLAO J. 24(2), 122 (1998); O’Brien, W., Invest. Opthalmol. Vis. Sci., 32 (9), 2455 (1991);<br></p>Fórmula:C10H12N2O7Cor e Forma:NeatPeso molecular:272.21Hydroxy Urea-15N
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH415NNO2Cor e Forma:NeatPeso molecular:77.05(1R,5R,6R)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic Acid Ethyl Ester
CAS:Produto Controlado<p>Applications This compound is an isomer of compound (E925685) used in the synthesis of neuraminidase inhibitors.<br>References Jarinrat K. et al.: Bioorg. Med. Chem. Lett., 20, 2152 (2012);<br></p>Fórmula:C14H22O4Cor e Forma:NeatPeso molecular:254.325-Hydroxymethyl-N,N-dimethyltryptamine
CAS:Produto Controlado<p>Applications Degradation product of Sumatriptan Succinate (S810000).<br>References Xu, X. et al.: J. Pharmaceut. Biomed. 367, 26 (2001)<br></p>Fórmula:C13H18N2OCor e Forma:WhitePeso molecular:218.296-Oxo-(S,S)-Palonosetron (~90%)
CAS:Produto Controlado<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Fórmula:C19H22N2O2Pureza:~90%Cor e Forma:NeatPeso molecular:310.39Valbenazine (~90% Purity)
CAS:Produto Controlado<p>Applications Valbenzine is a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.<br>References O'Brien, C. et al.: Movement Dis., 30, 1681 (2015);<br></p>Fórmula:C24H38N2O4Pureza:~90%Cor e Forma:NeatPeso molecular:418.571-Bromoethyl Acetate (~90%)
CAS:Produto Controlado<p>Applications 1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of antibiotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zakrzewski, J. et al.: Pol. J. Chem. Technol., 8, 83 (2006); Kamachi, H. et al.: J. Antibiot., 41, 1602 (1988);<br></p>Fórmula:C4H7BrO2Pureza:~90%Cor e Forma:NeatPeso molecular:167.0Tenofovir Bis(L-alanine Isopropyl Ester) Amide
CAS:Produto ControladoFórmula:C21H36N7O6PCor e Forma:NeatPeso molecular:513.53Alphenal
CAS:Produto Controlado<p>Applications Barbituric Acid (B118650) derivative with anti-convulsive properties. Controlled Substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carissime, M. et al.: Farmac. Edi. Sci., 17, 390 (1962); Harvey, D.J. et al.: Drug. Metab. Disp., 5, 527 (1977);<br></p>Fórmula:C13H12N2O3Cor e Forma:NeatPeso molecular:244.25Mono-POC Tenofovir 6-Isopropyl Carbamate (Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Fórmula:C18H28N5O9PCor e Forma:White SolidPeso molecular:489.42m-Hydroxyhippuric Acid-13C2, 15N
CAS:<p>Applications m-Hydroxyhippuric Acid-13C2, 15N is labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human.<br>References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)<br></p>Fórmula:C713C2H915NO4Cor e Forma:White To Off-WhitePeso molecular:198.151-(6-Amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide
CAS:Produto ControladoFórmula:C10H10N8OCor e Forma:NeatPeso molecular:258.241-Nitroso-3,5-dimethyladamantane
CAS:Produto ControladoFórmula:C12H19NOCor e Forma:NeatPeso molecular:193.285nPOC-POC Tenofovir(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications An impurity of Tenofovir (T018500(P)). Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C19H30N5O10PCor e Forma:NeatPeso molecular:519.44rac-Clopidogrel Hydrogen Sulfate
CAS:Produto Controlado<p>Applications rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010); Defreyn, G. et al.: Thromb. Haemo., 65, 186 (1991);<br></p>Fórmula:C16H16ClNO2S·H2O4SCor e Forma:Off-WhitePeso molecular:419.90(+)-9-deMe-DTBZ
CAS:<p>Applications (+)-9-deMe-DTBZ is a desmethyl derivative of Tetrabenzine (T284000), a dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Fórmula:C18H27NO3Cor e Forma:NeatPeso molecular:305.41[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
CAS:Produto Controlado<p>Applications [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C15H18N5O4PCor e Forma:NeatPeso molecular:363.31Methotrexate-d3 (Technical Grade) (100ug/mL in Methanol with 1% 0.1N NaOH)
CAS:Produto ControladoFórmula:C20H19D3N8O5Cor e Forma:Single SolutionPeso molecular:457.46Glycylglycyl-L-tyrosine
CAS:<p>Applications Fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>Fórmula:C13H17N3O5Cor e Forma:NeatPeso molecular:295.2912(R)-Methotrexate-d3 (Technincal Grade)
CAS:Produto ControladoFórmula:C20H19D3N8O5Cor e Forma:NeatPeso molecular:457.46Chloroformic Acid Chloromethyl Ester
CAS:Produto Controlado<p>Stability Very Very Moisture sensitive<br>Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);<br></p>Fórmula:C2H2Cl2O2Cor e Forma:Colourless OilyPeso molecular:128.943-Descyano Febuxostat Ethyl Ester
CAS:Produto Controlado<p>Applications 3-Descyano Febuxostat Ethyl Ester is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C17H21NO3SCor e Forma:NeatPeso molecular:319.425-Aminoimidazole-4-carboxamide-13C2,15N Hydrochloride Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Fórmula:C2C2H615NN3O·HClCor e Forma:BrownPeso molecular:165.556N10-Monodesmethyl Rizatriptan
CAS:Produto Controlado<p>Impurity Rizatriptan EP Impurity I<br>Applications N10-Monodesmethyl Rizatriptan (Rizatriptan EP Impurity I) is a metabolite of Rizatriptan.<br>References Dechant, K., et al.: Drugs, 43, 776 (1992), Castro, J., et al.: Bioorg. Med. Chem. Lett., 3, 993 (1993), Lee, Y., et al.: Biopharm. Drug Dispos., 19, 577 (1998), Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004),<br></p>Fórmula:C14H17N5Cor e Forma:NeatPeso molecular:255.32p-Chlorophenylcyanoguanidine
CAS:Produto Controlado<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Fórmula:C8H7ClN4Cor e Forma:NeatPeso molecular:194.624-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide
CAS:Produto Controlado<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 4-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide is an intermediate in the synthesis of 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) (A609165), which is an antimigraine agent. A Sumatriptan intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H18ClN3O2SCor e Forma:NeatPeso molecular:303.81nPOC-POC Tenofovir Fumarate(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Fórmula:C19H30N5O10P·C4H4O4Cor e Forma:White To Off-WhitePeso molecular:635.51Febuxostat 67M-2
CAS:Produto Controlado<p>Applications Febuxostat 67M-2 is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation.<br>References Du, J., et al.: Handbook of Metabolic Pathways of Xenobiotics, 4, 1395 (2014)<br></p>Fórmula:C16H16N2O4SCor e Forma:NeatPeso molecular:332.37N-(5-Aminopentyl) Methotrexate Amide
CAS:Produto Controlado<p>Applications The 5-aminopentyl amide derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Fan, J. et al.: J. Biol. Chem., 266, 14862 (1991);<br></p>Fórmula:C25H34N10O4Cor e Forma:NeatPeso molecular:538.6Sumatriptan N-Oxide
CAS:Produto Controlado<p>Impurity Sumatriptan EP Impurity D<br>Stability Hygroscopic, Unstable in DMSO<br>Applications Sumatriptan N-Oxide (Sumatriptan EP Impurity D) is the degradation product of the antimigraine drug Sumatriptan (S810000).<br>References Xu, X. et al.: J. Pharmac. Biomed. Anal., 26, 367 (2001); Cheng, K.N. et al.: J. Pharmac. Biomed. Anal., 17, 399 (1998);<br></p>Fórmula:C14H21N3O3SCor e Forma:Light Beige To Light BrownPeso molecular:311.40rac-Clopidogrel Carboxylic Acid Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications rac-Clopidogrel Carboxylic Acid Hydrochloride is a salt metabolite of rac-Clopidogrel.<br></p>Fórmula:C15H15Cl2NO2SCor e Forma:NeatPeso molecular:344.26D-Alanine Isopropyl Ester Hydrochloride
CAS:Produto Controlado<p>Applications D-Alanine Isopropyl Ester Hydrochloride is a chiral reagent used in the synthesis of nucleotide prodrugs such as (PSI-7977) for the treatment of hepatitis C. Also used in the preparation of synthetic sweeteners.<br>References Sofia, M. et al.: J. Med. Chem., 53, 7202 (2010); Mazur, R. et al.: J. Med. Chem., 16, 1284 (1973);<br></p>Fórmula:C6H14ClNO2Pureza:~90%Cor e Forma:NeatPeso molecular:167.63Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate
Produto Controlado<p>Applications Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate, is an impurity in the synthesis of Febuxostat n-Butyl Isomer (F229035).<br></p>Fórmula:C18H20N2O3SCor e Forma:NeatPeso molecular:344.43Thiamine Thiocarbamate
CAS:Produto Controlado<p>Applications Thiamine (T344185) impurity.<br></p>Fórmula:C14H20N4O3S2Cor e Forma:NeatPeso molecular:356.46Diethyl p-Toluenesulfonyloxymethylphosphonate
CAS:Produto Controlado<p>Applications Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Fórmula:C12H19O6PSCor e Forma:NeatPeso molecular:322.312,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Methotrexate intermediate.<br>References Feng, Y., et al.: J. Med. Chem., 49, 770 (2006),<br></p>Fórmula:C7H8N6O·ClHCor e Forma:YellowPeso molecular:228.641-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt
CAS:Produto ControladoFórmula:C25H33N5O4S2·CH2O2Cor e Forma:NeatPeso molecular:531.6946035-Aminoimidazole-4-carboxamide-15N2 Hydrochloride (>90%)
CAS:Produto ControladoFórmula:C4H7ClN215N2OPureza:>90%Cor e Forma:NeatPeso molecular:164.565-[1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]-6,7-dihydrothieno[3,2-c]pyridiniumBromide (~90%)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications One of the unknown impurities generated during the accelerated stability storage of Clopidogrel bisulfate tablets. Clopidogrel impurity.<br>References Gomez, Y., et al.: J. Pharm. Biomed. Anal., 34, 341 (2004), Ksycinska, H., et al.: J. Pharm. Biomed. Anal., 41, 533 (2006),<br></p>Fórmula:C16H15ClNO2S·BrPureza:~90%Cor e Forma:NeatPeso molecular:400.72Pemetrexed Disodium Heptahydrate
CAS:Produto Controlado<p>Applications Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Fórmula:C20H19N5O6·2Na·7H2OCor e Forma:NeatPeso molecular:597.48N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid
CAS:Produto Controlado<p>Applications N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid, referred to as Pemetrexed, is used in the treatment of malignant pleural mesothelioma (MPM).<br>References Pasello, G. et al.: Anticanc. Res., 32, 5393 (2012);<br></p>Fórmula:C20H21N5O6Cor e Forma:NeatPeso molecular:427.41Almotriptan-d6 Hydrochloride
CAS:Produto Controlado<p>Applications: Labelled Almotriptan (A575200). Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.<br>References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)<br></p>Fórmula:C172H6H19N3O2S·ClHCor e Forma:NeatPeso molecular:377.96Urea-d4
CAS:Produto Controlado<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>Fórmula:CD4N2OCor e Forma:NeatPeso molecular:64.088-13C-Uric Acid (contains ~1.5% unlabelled)
CAS:Produto Controlado<p>Applications 8-13C-Uric Acid is the labeled analogue of Uric Acid (U829200), a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006)<br></p>Fórmula:C413CH4N4O3Cor e Forma:NeatPeso molecular:169.1Oseltamivir Acid Methyl Ester Phosphate Salt
CAS:<p>Applications An impurity of the antiviral drug Oseltamivir (O700100). It is a COVID19-related research product.<br></p>Fórmula:C15H29N2O8PCor e Forma:NeatPeso molecular:396.37Caffeine-D10
CAS:Produto Controlado<p>Applications Caffeine-D10 is the labeled compound of Caffeine(C080100). Caffeine (Pentoxifylline EP Impurity F) is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor (1,2,3). Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses. Caffeine is a non-competitive inhibitor of acetylcholinesterase (3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Fórmula:C8D10N4O2Cor e Forma:NeatPeso molecular:204.252-Hydroxy-N-(pyridin-4-yl)butanamide
CAS:Produto Controlado<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>Fórmula:C9H12N2O2Cor e Forma:NeatPeso molecular:180.2Pemetrexed L-Glutamic Acid Trisodium Salt (~90%)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Pemetrexed L-Glutamic acid is an impurity of Pemetrexed (P219500). Pemetrexed impurity D.<br></p>Fórmula:C25H25N6O9·3NaPureza:~90%Cor e Forma:NeatPeso molecular:622.47(N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer
CAS:Produto Controlado<p>Impurity Zolmitriptan USP Related Compound F<br>Stability Hygroscopic<br>Applications (N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer (Zolmitriptan USP Related Compound F) is an impurity from the synthesis of Zolmitriptan (Z639000). Zolmitriptan is a Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>Fórmula:C38H53N7O4Pureza:>90%Cor e Forma:NeatPeso molecular:671.872-Oxo Clopidogrel-13C,d3 Hydrochloride(Mixture of Diastereomers)
CAS:Produto ControladoFórmula:C1513CH14D3Cl2NO3SCor e Forma:NeatPeso molecular:378.29Picolinamide
CAS:Produto Controlado<p>Applications A nicotinic acid derivative for prevention and treatment of cancer by activating RUNX3 gene.<br>References Ludwig, et al.: Cancer Res., 50, 2470 (1990), Gupta., et al.: Biomed. Environ. Sci., 13,122 (2000), Cai., et al.: J. Med. Chem., 46, 2474 (2003),<br></p>Fórmula:C6H6N2OCor e Forma:NeatPeso molecular:122.12Methotrexate Tetraglutamate Trifluoroacetate
CAS:Produto Controlado<p>Applications Methotrexate Tetraglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C35H43N11O14xC2HF3O2Cor e Forma:NeatPeso molecular:841.782-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS:Produto Controlado<p>Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.<br></p>Fórmula:C16H18ClN5O7Cor e Forma:NeatPeso molecular:427.80Sumatriptan Hydroxy-Oxindole Impurity (Sumatriptan Impurity 1)
CAS:Produto Controlado<p>Applications Sumatriptan Impurity 1, is an impurity of Sumatriptan (S810000), which is a serotonin 5HT1-receptor agonist, used for the treatment of migraine headaches.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988), Doenicke, A., et al.: Lancet 1, 1309 (1988),<br></p>Fórmula:C14H21N3O4SCor e Forma:NeatPeso molecular:327.4Tetrabenazine
CAS:Produto Controlado<p>Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Fórmula:C19H27NO3Cor e Forma:NeatPeso molecular:317.42Caffeidine Acid
CAS:Produto Controlado<p>Applications Caffeidine Acid is a degradation compound of Caffeine (C080100), which is a central nervous system stimulant.<br>References Kigasawa, K., et al.: Chem. Pharm. Bull., 22, 2448 (1974); Peinhardt, G.: Pharmazie, 46, 812 (1991); Kumar, R., et al.: Carcinogenesis, 13, 2179 (1992);<br></p>Fórmula:C8H12N4O3Cor e Forma:NeatPeso molecular:212.21Meropenem EP Impurity A
<p>Meropenem EP Impurity A is a synthetic, high purity, drug product that is used as an impurity standard for Meropenem. It has been synthesized from a custom synthesis and is available in both natural and synthetic form. This impurity can be used to investigate the metabolism of Meropenem and to determine its stability in different environments. The HPLC analysis of this impurity is available as a pharmacopoeia standard.</p>Fórmula:C17H27N3O6SPureza:Min. 95%Peso molecular:401.48 g/molAllopurinol impurity E
CAS:<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Fórmula:C7H9N3O3Pureza:Min. 95%Peso molecular:183.16 g/mol1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS:<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Fórmula:C8H9NO2Pureza:Min. 95%Peso molecular:151.16 g/mol5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS:<p>5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.</p>Fórmula:C16H20I3N3O8Pureza:Min. 95%Peso molecular:763.06 g/molLysine-methotrexate
CAS:<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>Fórmula:C21H27N9O3Pureza:Min. 95%Peso molecular:453.5 g/molPemetrexed impurity C
CAS:<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Fórmula:C40H40N10O13Pureza:Min. 95%Peso molecular:868.81 g/mol3,4-Dihydro naratriptan
CAS:<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Fórmula:C17H23N3O2SPureza:Min. 95%Peso molecular:333.45 g/mol(S)-Tenofovir
CAS:<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Fórmula:C9H14N5O4PPureza:99.9%Cor e Forma:SolidPeso molecular:287.214-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C20H27N4O4S2•ClPureza:Min. 95%Peso molecular:487.04 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS:<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Fórmula:C14H18I3N3O6Pureza:Min. 95%Peso molecular:705.02 g/molClopidogrel Impurity A
CAS:<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Fórmula:C15H15Cl2NO2SPureza:Min. 95%Peso molecular:344.26 g/mol2,4-Diamino-7-pteridinemethanol
CAS:<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Fórmula:C7H8N6OPureza:Min. 95%Peso molecular:192.18 g/molAllopurinol impurity A
CAS:<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>Pureza:Min. 95%Methotrexate-5-monomethyl ester
CAS:<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Fórmula:C21H24N8O5Pureza:Min. 95%Peso molecular:468.47 g/molAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Fórmula:C5H4N4NaOPureza:99.93%Cor e Forma:SolidPeso molecular:159.1Zolmitriptan related compound D
CAS:<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Fórmula:C19H25N3O4Pureza:Min. 95%Peso molecular:359.42 g/mol3-(Formylamino)-1H-pyrazole-4-carboxamide
CAS:<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>Fórmula:C5H6N4O2Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:154.13 g/molMercaptopurine impurity standard
CAS:<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>Pureza:Min. 95%OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39Migalastat
CAS:<p>Migalastat (GR181413A free base) is an orally administered, competitive inhibitor of α-galactosidase A (α-Gal A), demonstrating an IC50 value of 0.04 μM against</p>Fórmula:C6H13NO4Cor e Forma:SolidPeso molecular:163.17Neopterin
CAS:<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Fórmula:C9H11N5O4Pureza:99.54%Cor e Forma:SolidPeso molecular:253.21Palonosetron
CAS:<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Fórmula:C19H24N2OPureza:98%Cor e Forma:SolidPeso molecular:296.41Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Fórmula:C28H52N5O5PPureza:99.83%Cor e Forma:SolidPeso molecular:569.72Ormetoprim
CAS:<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Fórmula:C14H18N4O2Pureza:99.92%Cor e Forma:SolidPeso molecular:274.32Tenofovir diphosphate
CAS:<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Fórmula:C9H16N5O10P3Cor e Forma:SolidPeso molecular:447.17Codeine Phosphate CII
CAS:Produto Controlado<p>Concentrates of poppy straw; buprenorphine (inn) codein</p>Fórmula:C18H21NO3·H3O4PH2OCor e Forma:White Crystalline PowderPeso molecular:406.37 g/molMethotrexate-1-monomethyl ester
CAS:<p>Methotrexate-1-monomethyl ester is an impurity found in methotrexate, a drug used to treat cancer and autoimmune disorders. Methotrexate-1-monomethyl ester is a white to off-white crystalline solid that has been synthesized as a custom synthesis. It is used as an analytical standard for the determination of methotrexate in biological fluids and tissues. The chemical purity of this compound can be determined by HPLC, which allows for the identification of any impurities that may be present. Methotrexate-1-monomethyl ester is also used as a pharmacopoeia standard for methotrexate and its metabolites.</p>Fórmula:C21H24N8O5Pureza:Min. 95%Peso molecular:468.47 g/molN-Hydroxymethyl Sumatriptan
CAS:<p>N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).</p>Fórmula:C15H23N3O3SPureza:Min. 95%Peso molecular:325.43 g/mol1-Bromo-3,5-dimethyladamantane
CAS:<p>Intermediate in the synthesis of memantine</p>Fórmula:C12H19BrPureza:Min. 95%Peso molecular:243.18 g/molN-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic acid
CAS:<p>N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-gamma-glutamyl-L-glutamic acid is used as a research and development purity standard. It is a white crystalline powder that is soluble in water and ethanol. N-[4-[2-(2Amino 4,7dihydro 4oxo 3Hpyrrolo 2,3d]pyrimidin 5yl)ethyl]benzoyl]-L gamma glutamyl L glutamic acid has CAS number 144051 68 3. The drug product is a synthetic compound with high purity. It has been shown to be an analytical reference substance for HPLC standards and to have niche applications in metabolism studies of other drugs.</p>Fórmula:C25H28N6O9Pureza:Min. 95%Peso molecular:556.52 g/molSumatriptan EP Impurity A
CAS:<p>Sumatriptan EP Impurity A is a metabolite of sumatriptan, a drug product that is used for the treatment of migraine headaches. Sumatriptan EP Impurity A is a natural metabolite of sumatriptan and has been found to be an analytical impurity in the drug product. It has been shown to have anti-inflammatory properties and may be useful for treating arthritis. This impurity can also be synthesized by chemical synthesis or recombinant DNA technology.</p>Fórmula:C27H37N5O2SPureza:Min. 95%Peso molecular:495.68 g/molClopidogrel EP Impurity B hydrochloride
CAS:<p>Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C16H16ClNO2S•HClPureza:Min. 95%Peso molecular:358.28 g/molErgotamine Tartrate
CAS:Produto Controlado<p>Ergotamine and its salts</p>Fórmula:(C33H35N5O5)2·C4H6O6Cor e Forma:White Yellow PowderPeso molecular:1162.52764Butalbital CIII
CAS:Produto Controlado<p>Allobarbital (inn), amobarbital (inn), barbital (inn), butalbital (inn), butobarbital, cyclobarbital(inn), methylphenobarbital (inn), etc.</p>Fórmula:C11H16N2O3Cor e Forma:White PowderPeso molecular:224.11609PF 184
CAS:<p>IKKβ inhibitor</p>Fórmula:C32H32ClFN6O4Pureza:98%Cor e Forma:SolidPeso molecular:619.09Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Fórmula:C14H17N3OCor e Forma:SolidPeso molecular:243.3Miglustat hydrochloride
CAS:<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Fórmula:C10H22ClNO4Pureza:99.85%Cor e Forma:SolidPeso molecular:255.74Sumatriptan 3-hydroxy-2-oxo impurity
CAS:<p>Please enquire for more information about Sumatriptan 3-hydroxy-2-oxo impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C14H21N3O4SPureza:Min. 95%Peso molecular:327.4 g/molSorivudine
CAS:<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Fórmula:C11H13BrN2O6Pureza:99.74%Cor e Forma:SolidPeso molecular:349.13MRS2500
CAS:<p>MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.</p>Fórmula:C13H18IN5O8P2Pureza:98%Cor e Forma:SolidPeso molecular:561.16Porphobilinogen
CAS:<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Fórmula:C10H14N2O4Pureza:98%Cor e Forma:SolidPeso molecular:226.231-Benzyl-5-phenylbarbituric acid, 98+%
CAS:<p>1-Benzyl-5-phenylbarbituric acid is useful as a pharmaceutical intermediate in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar p</p>Fórmula:C17H14N2O3Pureza:98+%Cor e Forma:Powder, White to creamPeso molecular:294.31Open Ring N-Methyl Clopidogrel Hydrochloride (methyl (S)-2-(2-chlorophenyl)-2-(methyl(2-(thiophen-2-yl)ethyl)amino)acetate, hydrochloride) (DISCONTINUED)
CAS:<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Fórmula:C16H18ClNO2S·HClCor e Forma:White Off-White SolidPeso molecular:359.05136Ergotaminine
CAS:<p>Alkaloids of rye ergot and their derivatives; salts thereof, nesoi</p>Fórmula:C33H35N5O5Cor e Forma:White Off-White Light Grey Crystalline PowderPeso molecular:581.26382Ref: 4Z-P-217030
Produto descontinuadoRef: 4Z-P-127005
Produto descontinuadoRef: 4Z-T-144004
Produto descontinuadoRef: 4Z-T-02196
Produto descontinuadoRef: 4Z-I-084003
Produto descontinuadoRef: 4Z-T-02218
Produto descontinuadoRef: 4Z-T-02103
Produto descontinuadoTemozolomide Impurity 18
CAS:Fórmula:C4H3N4O2·ClCor e Forma:Pale Pink SolidPeso molecular:139.09 35.45Ref: 4Z-T-3427
Produto descontinuadoRef: 4Z-C-13102
Produto descontinuadoRef: 4Z-T-0237
Produto descontinuadoRef: 4Z-O-11136
Produto descontinuadoRef: 4Z-T-0238
Produto descontinuadoRef: 4Z-G-178017
Produto descontinuadoRef: 4Z-U-069
Produto descontinuadoRef: 4Z-T-6046
Produto descontinuadoRef: 4Z-P-5317
Produto descontinuadoRef: 4Z-O-11138
Produto descontinuado2-Fluoroacetaldehyde 2,4-Dinitrophenylhydrazone
CAS:Fórmula:C8H7FN4O4Cor e Forma:Off-White SolidPeso molecular:242.17Ref: 4Z-P-10303
Produto descontinuadoRef: 4Z-O-11140
Produto descontinuadoRef: 4Z-G-2434
Produto descontinuadoRef: 4Z-M-7054
Produto descontinuadoRef: 4Z-P-10309
Produto descontinuadoRef: 4Z-O-0324
Produto descontinuadoRef: 4Z-T-8432
Produto descontinuadoRef: 4Z-M-7036
Produto descontinuadoRef: 4Z-N-056026
Produto descontinuado
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