Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Deshydroxyethoxy Ticagrelor
CAS:<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Fórmula:C21H24F2N6O3SCor e Forma:White To Off-WhitePeso molecular:478.52Pimozide N-Oxide
CAS:<p>Applications Pimozide N-Oxide is an impurity of Pimozide (P447800) with hERG inhibitory activity. Pimozide impurity E.<br></p>Fórmula:C28H29F2N3O2Cor e Forma:Off White PowderPeso molecular:477.54N-Methylformamide
CAS:Produto Controlado<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>Fórmula:C2H5NOCor e Forma:NeatPeso molecular:59.074-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide
CAS:<p>Impurity Amisulpride EP Impurity G<br>Applications 4-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide is an impurity of Amisulpride (A633250). Amisulpride EP Impurity G<br></p>Fórmula:C17H27N3O4SCor e Forma:Off White PowderPeso molecular:369.479Tazarotenic Acid
CAS:Produto Controlado<p>Applications Tazarotenic acid is the major active metabolite of Tazarotene (T010050).<br>References Nagpal, S., et al.: J. Biol. Chem., 270, 923 (1995), Madhu, C., et al.: J. Pharm. Sci., 86, 972 (1997), Attar, M., et al.: Drug Metab. Dispos., 31, 476 (2003),<br></p>Fórmula:C19H17NO2SCor e Forma:NeatPeso molecular:323.416-CHLORO-1-(6-FLUOROPYRIDIN-2-YL)-1H-PYRAZOLO[4,3-C]PYRIDINE
CAS:Pureza:95.0%Peso molecular:248.64999389648438Felbamate
CAS:Produto Controlado<p>Applications Antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Fórmula:C11H14N2O4Cor e Forma:NeatPeso molecular:238.244-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Fórmula:C14H13ClN2O2·HClCor e Forma:NeatPeso molecular:313.18Telmisartan-d4
CAS:Produto Controlado<p>Applications Telmisartan-d4 is deuterium labelled Telmisartan (T017000). Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W. et al.: Br. J. Pharmacol., 110, 245 (1993); Neutel, J.M. et al: Adv. Therap., 15, 206 (1998)<br></p>Fórmula:C33D4H26N4O2Cor e Forma:NeatPeso molecular:518.645-(4-Chlorobutyl)-1-cyclohexyltetrazole
CAS:Produto Controlado<p>Applications An impurity of Cilostazol (C441500(P)), which is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties and affects lipid levels in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Fórmula:C11H19ClN4Cor e Forma:Light YellowPeso molecular:242.752-(5-Nitropyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline
CAS:Pureza:97.0%Peso molecular:255.27699279785156Ref: 10-F511607
1gA consultar5gA consultar10gA consultar50mgA consultar100mgA consultar250mgA consultar1-(Mercaptomethyl)cyclopropaneacetic Acid
CAS:Produto Controlado<p>Applications An intermediate of Montelukast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C6H10O2SCor e Forma:NeatPeso molecular:146.212-Amino-4-thiazoleacetic Acid
CAS:Produto ControladoFórmula:C5H6N2O2SCor e Forma:NeatPeso molecular:158.183-(2,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
CAS:Pureza:98%Peso molecular:282.35998535156258(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixture of Regioisomers)
CAS:Produto Controlado<p>Impurity Omeprazole EP Impurity F+Omeprazole EP Impurity G<br>Stability Sample unstable under MS condition<br>Applications 8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one(Mixture of Regioisomers) (Omeprazole EP Impurity F+Omeprazole EP Impurity G) is a mixture of regioisomers of Omeprazole Impurity.<br>References Rackur, G., et al.: Biochem. Biophys. Res. Commmun., 128, 477 (1985),<br></p>Fórmula:C16H13N3O2SCor e Forma:NeatPeso molecular:311.364-(Hydroxymethyl)benzoic Acid
CAS:Produto ControladoFórmula:C8H8O3Cor e Forma:NeatPeso molecular:152.151-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine (~10% inorganics)
CAS:Produto Controlado<p>Impurity Apremilast EP Impurity H<br>Applications 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H<br>References Ruchelman, A., et al.: Tetrahedron Asymmetr., 26, 553-559 (2015);<br></p>Fórmula:C12H19NO4SCor e Forma:NeatPeso molecular:273.353-Hydroxy Medetomidine
CAS:Produto Controlado<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Fórmula:C13H16N2OCor e Forma:NeatPeso molecular:216.28[2-(1H-indol-3-yl)ethyl](3-pyridinylmethyl)amine hydrobromide
CAS:Pureza:95.0%Peso molecular:332.24499511718754-((3-Chloro-2,4-difluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Pureza:97.0%Peso molecular:337.7099914550781Benzyl (3-fluoro-4-morpholinophenyl)carbamate
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:330.35900878906253-Pyridylmagnesium bromide, 0.25M THF
CAS:Pureza:97.0%Cor e Forma:LiquidPeso molecular:182.30299377441406Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate
CAS:Produto Controlado<p>Applications Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate (cas# 144172-24-7) is a useful research chemical. It is an intermediate in the synthesis of IN-KG 433 (I627995). IN-KG 433 is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>Fórmula:C11H9O4ClCor e Forma:NeatPeso molecular:240.631,2-DIMETHYL-4-OXO-N-PHENYL-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE
CAS:Pureza:95.0%Peso molecular:292.33801269531252-Oxo-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridine-3-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:221.13499450683594N-Nitrosooxprenolol
CAS:Produto ControladoFórmula:C15H22N2O4Cor e Forma:Light YellowPeso molecular:294.3462,3-Diphenylquinoxaline
CAS:Pureza:98.0%Cor e Forma:Solid, White - Pale reddish yellow powderPeso molecular:282.346008300781252-(CHLOROMETHYL)-4-(2,2,3,3,4,4,4-HEPTAFLUOROBUTOXY)PYRIDINE
CAS:Pureza:95.0%Peso molecular:325.6099853515625PD 169,316
CAS:<p>M02298 - PD 169,316</p>Fórmula:C20H13FN4O2Pureza:>98%Cor e Forma:SolidPeso molecular:360.3479919433594Levomepromazine EP Impurity D
Produto ControladoFórmula:C32H33N3O2S2Cor e Forma:NeatPeso molecular:555.8O-Pentaacetyl O-Desethyl Dapagliflozin
CAS:Fórmula:C29H31ClO11Cor e Forma:White To Off-WhitePeso molecular:591.003Valsartan n-Propyl Impurity
CAS:Produto Controlado<p>Impurity Valsartan Related Compound B<br>Applications Valsartan n-Propyl is an impurity in the synthesis of Valsartan (V095750). Valsartan USP Related Compound B.<br>References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 31, 329 (2003), Carlucci, G., et al.: Anal. Lett., 33, 2491 (2000), Cagigal, E., et al.: Talanta, 54, 1121 (2001),<br></p>Fórmula:C23H27N5O3Cor e Forma:WhitePeso molecular:421.49Pyraclostrobin
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Pyraclostrobin is a fungicide for use in seed grass and food crops. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Fórmula:C19H18ClN3O4Cor e Forma:YellowPeso molecular:387.82Omeprazole-d3
CAS:Produto Controlado<p>Applications Labelled Omeprazole, which binds covalently to proton pump, it inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C172H3H16N3O3SCor e Forma:NeatPeso molecular:348.436-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-((1-methylpiperidin-4-yl)amino)quinazolin-7-ol (trihydrochloride)
Pureza:98%Peso molecular:509.9Edoxaban 4-Carboxylic Acid Hydrochloride
CAS:Produto ControladoFórmula:C22H25ClN6O5S·xHClCor e Forma:NeatPeso molecular:520.99 + x(36.46)Tazarotene Thiochromane Dimer
CAS:<p>Applications Tazarotene Thiochromane DImer is an impurity of Tazarotene (T010050), an acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C26H26S2Cor e Forma:NeatPeso molecular:402.6146
![6-CHLORO-1-(6-FLUOROPYRIDIN-2-YL)-1H-PYRAZOLO[4,3-C]PYRIDINE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF386500.webp&w=3840&q=75)
![8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixtur…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM262560.webp&w=3840&q=75)
amine hydrobromide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF361266.webp&w=3840&q=75)
