Peptídeos e Proteínas
Os peptídeos são cadeias curtas de aminoácidos ligadas por ligações peptídicas, enquanto as proteínas são cadeias mais longas e complexas de aminoácidos que podem adotar estruturas tridimensionais funcionais. Ambos os tipos de compostos são essenciais para diversas funções biológicas, como a catálise de reações (enzimas), a defesa imunológica (anticorpos) e a sinalização celular. As proteínas possuem uma estrutura hierárquica que inclui a sequência de aminoácidos, bem como as estruturas secundária, terciária e quaternária. Os peptídeos são utilizados em terapias farmacológicas e cosméticas devido às suas propriedades biológicas específicas, como no tratamento de doenças metabólicas ou na melhoria da regeneração celular. As proteínas, por sua vez, possuem aplicações em biotecnologia, nutrição e medicina regenerativa.
Na CymitQuimica, oferecemos peptídeos e proteínas de alta pureza para pesquisa em biotecnologia e aplicações terapêuticas.
Foram encontrados 3143 produtos de "Peptídeos e Proteínas"
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Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.91MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFórmula:C16H15ClFNPureza:99.17%Cor e Forma:SolidPeso molecular:275.75Liraglutide
CAS:<p>Liraglutide (Liraglutida) is a synthetic analog of GLP-1, an agonist of the GLP-1 receptor. Liraglutide is an antidiabetic agent. Cost effective and quality assured.</p>Fórmula:C172H265N43O51Pureza:97.65% - 99.04%Cor e Forma:SolidPeso molecular:3751.25Nateglinide
CAS:Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.Fórmula:C19H27NO3Pureza:99.93% - 99.94%Cor e Forma:White Crystalline PowderPeso molecular:317.42Romidepsin
CAS:Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Cor e Forma:SolidPeso molecular:540.7Carfilzomib (2R,4S)-Diol
CAS:Produto Controlado<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Cor e Forma:NeatPeso molecular:737.93(1R,2R)-Bortezomib
CAS:<p>Impurity Bortezomib USP Related Compound A<br>Applications (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C19H25BN4O4Pureza:>85%Cor e Forma:NeatPeso molecular:384.24L-Prolinamide
CAS:<p>Applications Proline based organocatalyst.<br>References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),<br></p>Fórmula:C5H10N2OCor e Forma:White SolidPeso molecular:114.146L-Valine-d8
CAS:Produto Controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C52H8H3NO2Cor e Forma:NeatPeso molecular:125.20(2R,4R)-Sacubitril
CAS:<p>Applications (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Cor e Forma:NeatPeso molecular:411.491L-Methionine Sulfoxide
CAS:<p>Stability Temperature Sensitive, Hygroscopic<br>Applications An intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.<br>References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008), Balog, E., et al.: Biochem., 48, 3005 (2009),<br></p>Fórmula:C5H11NO3SCor e Forma:White To BeigePeso molecular:165.214-Methylbenzenesulfonic Acid Monohydrate
CAS:Produto Controlado<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>Fórmula:C7H8O3S·H2OCor e Forma:WhitePeso molecular:190.223,3',5'-Triiodo-L-thyronine
CAS:Fórmula:C15H12I3NO4Cor e Forma:Light Beige To GreyPeso molecular:650.97Dihydro Cyclosporin A
CAS:Produto Controlado<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>Fórmula:C62H113N11O12Cor e Forma:WhitePeso molecular:1204.63N-Acetyl-L-carnosine
CAS:Produto Controlado<p>Applications Used in the treatment of cataracts and in the treatment of UV-induced immunosuppression. May act with with lipoic acid (L468725) to reverse age-related metabolic decline and also the indicies of oxidative stress.<br>References Babizhayev, M., et al.: J. Pharmacol. Toxicol., 1, 201 (2006), Min, J., et al.: J. Neurosci. Res., 86, 2984 (2008), Babizhayev, M., et al.: J. Drug Target., 17, 36 (2009); Hagen et. al, PNAS 99: 1870 (2002); Liu et. al, PNAS 99, 2356 (2002)<br></p>Fórmula:C11H16N4O4Cor e Forma:Off-WhitePeso molecular:268.27Sugammadex Sodium-deuterated
CAS:Produto Controlado<p>Applications Sugammadex Sodium-deuterated, is the labaled analogue of Sugammadex Sodium (S698100), which is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents and may have many potential peri-operative benefits.<br>References Welliver, M., et al.: Drug Des. Devel. Ther., 2, 49 (2008);<br></p>Fórmula:C72H104Na8O48S8forundeuteratedCor e Forma:NeatPeso molecular:2178.0066-Perdeoxy-6-perchloro-γ-cyclodextrin, >90%
CAS:Fórmula:C48H72Cl8O32Pureza:>90%Cor e Forma:NeatPeso molecular:1444.69Bivalirudin Trifluoroacetic Acid Salt
CAS:<p>Applications Bivalirudin Trifluoroacetic Acid Salt is an anticoagulant drug that is a direct thrombin inhibitor. It is used for treatment of acute coronary syndromes, and is a safer alternative to heparin due to lower rates of bleeding as an adverse effect of anticoagulant in patients.<br>References Stone, G., et al.: N. Engl. J. Med, 355, 2203 (2006); Stone, G., et al.: N Engl J Med, 358, 2218 (2008);<br></p>Fórmula:C98H138N24O33·(C2HF3O2)xCor e Forma:NeatPeso molecular:2180.2911402L-Carnitine-L-tartrate
CAS:Produto Controlado<p>Applications L-Carnitine-L-tartrate (cas# 36687-82-8) is a useful research chemical.<br></p>Fórmula:C7H16NO3·C4H4O6Cor e Forma:White To Off-WhitePeso molecular:472.48(2S,4S)-Sacubitril
CAS:<p>Stability Moisture Sensitive<br>Applications (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Cor e Forma:NeatPeso molecular:411.49Dl-valine
CAS:Produto Controlado<p>Applications Dl-valine<br></p>Fórmula:C5H11NO2Cor e Forma:NeatPeso molecular:117.15N-Formyl Thyroxine
CAS:Produto Controlado<p>Impurity Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)<br>Applications N-Formyl Thyroxine (Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)) is a thyroxine derivative which showed less thyroid activity than Thyroxine Sodium (T425601).<br>References Basil, B., et al.: Br. J. Pharmacol. Chemother., 5, 315 (1950),<br></p>Fórmula:C16H11I4NO5Cor e Forma:NeatPeso molecular:804.88Cyclosporin B
CAS:<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C61H109N11O12Pureza:>80%Cor e Forma:NeatPeso molecular:1188.58L-Threonine
CAS:Produto Controlado<p>Applications L-enantiomer of Threonine. An essential amino acid for human development; last of the common amino acids to be discovered. Identified in oat protein.<br>References LeMaster, D.M., et al.: J. Biol. Chem., 257, 1224 (1982), Ballevre, O., et al.: Anal. Biochem., 193, 212 (1991), Roufs, J.B., et al.: Med. Hypotheses, 34, 20 (1991), Blin, O., et al.: J. Neurol., 239, 79 (1992),<br></p>Fórmula:C4H9NO3Cor e Forma:NeatPeso molecular:119.12N-Acetyl-L-methionine
CAS:Produto Controlado<p>Applications N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-stored platelets.<br>References D’Alessandro, A., et al.: Transfusion (Malden, MA, US), 60, S96 (2020)<br></p>Fórmula:C7H13NO3SCor e Forma:NeatPeso molecular:191.003,3’,5-Triiodo-D-thyronine
CAS:Produto Controlado<p>Applications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.<br>References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)<br></p>Fórmula:C15H12I3NO4Cor e Forma:Off-White To Light BrownPeso molecular:650.97N-Acetyl-DL-methionine
CAS:Produto Controlado<p>Applications C7H13NO3S (cas# 1115-47-5) is a useful research chemical.<br></p>Fórmula:C7H13NO3SCor e Forma:NeatPeso molecular:191.25N-Nitroso-D-proline
CAS:Produto Controlado<p>Applications A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.<br>References Nagasawa, H.T., et al.: J. Med. Chem., 16 (5), 583-585 (1973)<br></p>Fórmula:C5H8N2O3Cor e Forma:NeatPeso molecular:144.13Cyclosporin H
CAS:<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C62H111N11O12Cor e Forma:NeatPeso molecular:1202.61Boceprevir (>90%)
CAS:Produto ControladoFórmula:C27H45N5O5Pureza:>90%Cor e Forma:NeatPeso molecular:519.68(4R)-1-Methyl-4-propyl-L-proline Hydrochloride
CAS:Produto Controlado<p>Applications Proline derivative, and an intermediate in the production of biosynthetic antibiotics.<br></p>Fórmula:C9H17NO2·ClHCor e Forma:NeatPeso molecular:207.70L-Valine-13C5,15N
CAS:Produto Controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C5H1115NO2Cor e Forma:NeatPeso molecular:123.13,3’,5-Triiodo-L-thyronine 4’-O-Sulfate
CAS:<p>Applications 3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate is the sulfoconjugated metabolite of 3,3’,5-Triiodo-L-thyronine (T795380).<br>References Rooda, S.J. et al.: J. Clin. Endocrinol. Metab., 69, 552 (1989); Everts, M. E. et al.: Metab. Clin. Exp., 43, 1282 (1994); Pinna, G. et al.: Endocrinology, 143, 1789 (2002);<br></p>Fórmula:C15H12I3NO7SCor e Forma:NeatPeso molecular:731.04Methyltetrazine-Amine
CAS:Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.Fórmula:C10H11N5Pureza:97.59%Cor e Forma:Pink SolidPeso molecular:201.23Bortezomib Trimer
CAS:Produto Controlado<p>Applications Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C57H69B3N12O9Cor e Forma:NeatPeso molecular:1098.666Sacubitril-d4
CAS:Produto Controlado<p>Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C242H4H25NO5Cor e Forma:Light YellowPeso molecular:415.52(2S,4R)-Sacubitril
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Cor e Forma:Colourless To Off-WhitePeso molecular:411.49Cyclosporin AM 1 (>80%)
CAS:Produto Controlado<p>Applications A cyclosporine metabolite specifically inhibits growth of renal cells in culture.<br>References Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991), Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (2006), Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).<br></p>Fórmula:C62H111N11O13Pureza:>80%Cor e Forma:NeatPeso molecular:1218.613,3’,5-Triiodo-L-thyronine
CAS:Produto ControladoFórmula:C15H12I3NO4Cor e Forma:White To Off-WhitePeso molecular:650.973,5,3',5'-Tetraiodo Thyroacetamide
CAS:Produto Controlado<p>Impurity Levothyroxine Acetamide Impurity<br>Applications 3,5,3',5'-Tetraiodo Thyroacetamide is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br>References Andre, M., et al.: J. Chromatogr., 741, 146 (1996),<br></p>Fórmula:C14H9I4NO3Cor e Forma:Light Orange Colour To Light BrownPeso molecular:746.84N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Fórmula:C16H24N2O4Cor e Forma:White To Light BeigePeso molecular:308.37L-Methionine [R,S]-Sulfoximine
CAS:Produto Controlado<p>Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.<br>References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)<br></p>Fórmula:C5H12N2O3SCor e Forma:NeatPeso molecular:180.23N-Pyrazinylcarbonyl-L-phenylalanine
CAS:Produto Controlado<p>Applications Used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C14H13N3O3Cor e Forma:WhitePeso molecular:271.27[Des-Thr-ol8]-[D-Cys7]-Octreotide TFA
CAS:Produto ControladoFórmula:C45H57N9O9S2•x(C2HF3O2)Cor e Forma:NeatPeso molecular:932.1211402
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