Peptídeos e Proteínas
Os peptídeos são cadeias curtas de aminoácidos ligadas por ligações peptídicas, enquanto as proteínas são cadeias mais longas e complexas de aminoácidos que podem adotar estruturas tridimensionais funcionais. Ambos os tipos de compostos são essenciais para diversas funções biológicas, como a catálise de reações (enzimas), a defesa imunológica (anticorpos) e a sinalização celular. As proteínas possuem uma estrutura hierárquica que inclui a sequência de aminoácidos, bem como as estruturas secundária, terciária e quaternária. Os peptídeos são utilizados em terapias farmacológicas e cosméticas devido às suas propriedades biológicas específicas, como no tratamento de doenças metabólicas ou na melhoria da regeneração celular. As proteínas, por sua vez, possuem aplicações em biotecnologia, nutrição e medicina regenerativa.
Na CymitQuimica, oferecemos peptídeos e proteínas de alta pureza para pesquisa em biotecnologia e aplicações terapêuticas.
Foram encontrados 3151 produtos de "Peptídeos e Proteínas"
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L-Valine-13C5,15N
CAS:Produto Controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C5H1115NO2Cor e Forma:NeatPeso molecular:123.1Carfilzomib (2R,4S)-Diol
CAS:Produto Controlado<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Cor e Forma:NeatPeso molecular:737.93Boceprevir (>90%)
CAS:Produto ControladoFórmula:C27H45N5O5Pureza:>90%Cor e Forma:NeatPeso molecular:519.68Cyclosporin H
CAS:<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C62H111N11O12Cor e Forma:NeatPeso molecular:1202.61N-Acetyl-DL-methionine
CAS:Produto Controlado<p>Applications C7H13NO3S (cas# 1115-47-5) is a useful research chemical.<br></p>Fórmula:C7H13NO3SCor e Forma:NeatPeso molecular:191.25Thyroxine 4’-O-β-D-Glucuronide
CAS:<p>Applications Thyroxine 4-O-β-D-Glucuronide is a major metabolite and glucuronide conjugate of Thyroxine (T425600) formed via the glucuronidation of the phenyl hydroxyl group.<br>References Tong, Z. et al.: Drug Metab. Dispos., 35, 2203 (2007); West, C.D. et al.: J. Clin. INvest., 42, 1134 (1963);<br></p>Fórmula:C21H19I4NO10Cor e Forma:NeatPeso molecular:952.99Cyclosporin B
CAS:<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C61H109N11O12Pureza:>80%Cor e Forma:NeatPeso molecular:1188.58N-Formyl Thyroxine
CAS:Produto Controlado<p>Impurity Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)<br>Applications N-Formyl Thyroxine (Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)) is a thyroxine derivative which showed less thyroid activity than Thyroxine Sodium (T425601).<br>References Basil, B., et al.: Br. J. Pharmacol. Chemother., 5, 315 (1950),<br></p>Fórmula:C16H11I4NO5Cor e Forma:NeatPeso molecular:804.88(2S,4S)-Sacubitril
CAS:<p>Stability Moisture Sensitive<br>Applications (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Cor e Forma:NeatPeso molecular:411.49L-Carnitine-L-tartrate
CAS:Produto Controlado<p>Applications L-Carnitine-L-tartrate (cas# 36687-82-8) is a useful research chemical.<br></p>Fórmula:C7H16NO3·C4H4O6Cor e Forma:White To Off-WhitePeso molecular:472.48Bestatin
CAS:<p>Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.</p>Fórmula:C16H24N2O4Pureza:98% - 99.63%Cor e Forma:White Crystalline PowderPeso molecular:308.37Bivalirudin Trifluoroacetic Acid Salt
CAS:<p>Applications Bivalirudin Trifluoroacetic Acid Salt is an anticoagulant drug that is a direct thrombin inhibitor. It is used for treatment of acute coronary syndromes, and is a safer alternative to heparin due to lower rates of bleeding as an adverse effect of anticoagulant in patients.<br>References Stone, G., et al.: N. Engl. J. Med, 355, 2203 (2006); Stone, G., et al.: N Engl J Med, 358, 2218 (2008);<br></p>Fórmula:C98H138N24O33·(C2HF3O2)xCor e Forma:NeatPeso molecular:2180.29114026-Perdeoxy-6-perchloro-γ-cyclodextrin, >90%
CAS:Fórmula:C48H72Cl8O32Pureza:>90%Cor e Forma:NeatPeso molecular:1444.69N-Acetyl-L-carnosine
CAS:Produto Controlado<p>Applications Used in the treatment of cataracts and in the treatment of UV-induced immunosuppression. May act with with lipoic acid (L468725) to reverse age-related metabolic decline and also the indicies of oxidative stress.<br>References Babizhayev, M., et al.: J. Pharmacol. Toxicol., 1, 201 (2006), Min, J., et al.: J. Neurosci. Res., 86, 2984 (2008), Babizhayev, M., et al.: J. Drug Target., 17, 36 (2009); Hagen et. al, PNAS 99: 1870 (2002); Liu et. al, PNAS 99, 2356 (2002)<br></p>Fórmula:C11H16N4O4Cor e Forma:Off-WhitePeso molecular:268.27Dihydro Cyclosporin A
CAS:Produto Controlado<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>Fórmula:C62H113N11O12Cor e Forma:WhitePeso molecular:1204.633,3',5'-Triiodo-L-thyronine
CAS:Fórmula:C15H12I3NO4Cor e Forma:Light Beige To GreyPeso molecular:650.974-Methylbenzenesulfonic Acid Monohydrate
CAS:Produto Controlado<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>Fórmula:C7H8O3S·H2OCor e Forma:WhitePeso molecular:190.22(2R,4R)-Sacubitril
CAS:<p>Applications (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Cor e Forma:NeatPeso molecular:411.491L-Prolinamide
CAS:<p>Applications Proline based organocatalyst.<br>References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),<br></p>Fórmula:C5H10N2OCor e Forma:White SolidPeso molecular:114.146(4R)-1-Methyl-4-propyl-L-proline Hydrochloride
CAS:Produto Controlado<p>Applications Proline derivative, and an intermediate in the production of biosynthetic antibiotics.<br></p>Fórmula:C9H17NO2·ClHCor e Forma:NeatPeso molecular:207.70(1R,2R)-Bortezomib
CAS:<p>Impurity Bortezomib USP Related Compound A<br>Applications (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C19H25BN4O4Pureza:>85%Cor e Forma:NeatPeso molecular:384.24GSK1904529A
CAS:GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Fórmula:C44H47F2N9O5SPureza:98.2% - 99.76%Cor e Forma:SolidPeso molecular:851.96Desisobutyl-n-butyl Bortezomib
CAS:<p>Impurity Bortezomib N-Pentyl Impurity<br>Applications Desisobutyl-n-butyl Bortezomib is an impurity of Bortezomib (B675700). Bortezomib impurity 5.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lin, G., et al.: J. Biol. Chem., 283, 34423 (2008);<br></p>Fórmula:C19H25BN4O4Cor e Forma:NeatPeso molecular:384.24MK 677
CAS:<p>Applications MK-677 is a potent, non-peptide ghrelin receptor agonist.<br>References Kirstie, A., et al.: Mol. Pharmacol., 76, 802 (2009); Birgitte, H. et al.: Mol. Pharmacol., 75, 44 (2009)<br></p>Fórmula:C27H36N4O5S·CH4SO3Cor e Forma:NeatPeso molecular:624.80L-Valine-d8
CAS:Produto Controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C52H8H3NO2Cor e Forma:NeatPeso molecular:125.20Protoporphyrin-9
CAS:<p>Stability Light Sensitive<br>Applications Protoporphyrin-9 is the precursor to heme sites and chlorophyll.<br></p>Fórmula:C34H34N4O4Cor e Forma:NeatPeso molecular:562.665-9-Leuprolide xTFA Salt
CAS:Produto Controlado<p>Applications 5-9-Leuprolide is a metabolite of Leuprolide (L330590), a gonadotropin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors.<br>References Handelsman, David J., et al.: J. of Steroid Biochem. and Mol. Bio., 141, 113-120 (2014);Okada, Hiroaki, et al.: Pharma. Res., 8(6), 787-91 (1991)<br></p>Fórmula:C34H57N9O6·x(C2HF3O2)Cor e Forma:NeatPeso molecular:687.87+ x(114.02)Teduglutide
CAS:Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).Fórmula:C164H252N44O55SPureza:98.08%Cor e Forma:SolidPeso molecular:3752.084-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl Ester
CAS:Produto Controlado<p>Applications Remifentanil derivative.<br>References James, M.K., et al.: J. Pharmacol. Exp. Ther., 259, 712 (1991), Hoffman, W.E., et al.: Anesthesiology, 79, 107 (1993), Selinger, K., et al.: J. Pharm. Biomed. Anal., 12, 243 (1994), Richardson, T.D., et al.: Expert Opin. Drug Saf., 4, 643 (2005),<br></p>Fórmula:C20H24N2O2Cor e Forma:NeatPeso molecular:324.4168Bortezomib-D8 (Major)
CAS:Produto Controlado<p>Applications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells.d6-3%d7-10%d8-86%<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)<br></p>Fórmula:C19H17D8BN4O4Cor e Forma:Off-WhitePeso molecular:392.29N-2-(Hydroxyethyl)-L-valine-d4 (Technical grade)
CAS:Produto Controlado<p>Applications Labelled N-2-(Hydroxyethyl)-L-valine (H942300). Cotinine and N-(2-hydroxyethyl)valine are markers of passive exposure to tobacco smoke in children.<br>References Dempsey, D., et al.: Clin. Pharmacol. Ther., 67, 458 (2000), Smith, C., et al.: Food Chem. Toxicol., 41, 807 (20030,<br></p>Fórmula:C7H11D4NO3Cor e Forma:WhitePeso molecular:165.225-Oxo-DL-proline-d5
CAS:Produto Controlado<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Fórmula:C52H5H2NO3Cor e Forma:NeatPeso molecular:134.14N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
CAS:<p>Applications Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C15H15N3O3Cor e Forma:NeatPeso molecular:285.30N-Nitroso-D-proline
CAS:Produto Controlado<p>Applications A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.<br>References Nagasawa, H.T., et al.: J. Med. Chem., 16 (5), 583-585 (1973)<br></p>Fórmula:C5H8N2O3Cor e Forma:NeatPeso molecular:144.13Oxytocin Acetate
CAS:<p>Applications Oxytocin Acetate is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.<br>References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),<br></p>Fórmula:C43H66N12O12S2·C2H4O2Cor e Forma:White To Off-WhitePeso molecular:1067.24Methyltetrazine-Amine
CAS:Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.Fórmula:C10H11N5Pureza:97.59%Cor e Forma:Pink SolidPeso molecular:201.23N-Glycylproline
CAS:<p>Applications N-Glycylproline was found to exhibit anti-ischemic effects on the metabolism of neuroactive amino acids and indices of energy turnover in the neocortex of rats after experimental brain ischemia.<br>References Bashun, Z.N., et al.: Neurochem. J., 7, 39 (2013);<br></p>Fórmula:C7H12N2O3Cor e Forma:NeatPeso molecular:172.182Lisinopril (S,S,R)-Diketopiperazine (~90%)
CAS:<p>Impurity Lisinopril EP Impurity D<br>Stability Hygroscopic<br>Applications Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).<br>References 1. Goa, K. et al.: Drugs. 1996 Oct;52(4):564-88.<br></p>Fórmula:C21H29N3O4Pureza:~90%Cor e Forma:White To Off-WhitePeso molecular:387.471,2-Bismethylphenidate (Mixture of Diastereomers)
Produto Controlado<p>Applications 1,2-Bismethylphenidate is an impurity of methylphenidate (M325880), an CNS stimulant.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Fórmula:C23H27NO4Cor e Forma:NeatPeso molecular:381.46Lisinopril Cyclohexyl Analogue
CAS:Produto Controlado<p>Impurity Lisinopril EP Impurity F<br>Applications Lisinopril Cyclohexyl Analogue (Lisinopril EP Impurity F) is a Lisinopril (L468985) impurity.<br>References Paraskevas, G., et al.: J. Pharm. Biomed. Anal., 29, 865 (2002),<br></p>Fórmula:C21H37N3O5Cor e Forma:NeatPeso molecular:411.54β-Hydroxy Thyroxine (>90%)
CAS:Produto Controlado<p>Impurity Levothyroxine beta-Hydroxy Impurity / Levothyroxine beta-Hydroxy T4 Impurity<br>Applications It has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.<br>References Wawzone, S., et al.: J. Med. Chem., 6, 442 (1963),<br></p>Fórmula:C15H11I4NO5Pureza:>90%Cor e Forma:NeatPeso molecular:792.87N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:Produto ControladoFórmula:C19H24N4O2Cor e Forma:White To Off-WhitePeso molecular:340.41951-Nitrosopyrrolidine-2-carboxylic Acid
CAS:Produto Controlado<p>Applications 1-nitrosopyrrolidine-2-carboxylic acid (cas# 2571-28-0) is a useful research chemical.<br></p>Fórmula:C5H8N2O3Cor e Forma:NeatPeso molecular:144.129Methionine
CAS:<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>Fórmula:C5H11NO2SPureza:99.13% - 99.62%Cor e Forma:SolidPeso molecular:149.21(R)-Lisinopril Sodium Salt
CAS:<p>Applications R,S,S-Isomer of Lisinopril (L468985).<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)<br></p>Fórmula:C21H31N3NaO5Cor e Forma:NeatPeso molecular:428.48rhPTH (1-30) Trifluoroacetic Acid Salt Hydrate
Produto Controlado<p>Impurity Teriparatide Impurity<br>Applications A fragment of human parathyroid hormone (hPTH) peptide sequence containing the 30 N-terminal residues of hPTH.<br>References Niall, et al.: Proc. Natl. Acad. Sci., 71, 384 (1974);<br></p>Fórmula:C157H260N48O46S2•x(C2HF3O2)•y(H2O)Cor e Forma:NeatPeso molecular:3620.171140218Sacubitril Calcium
CAS:<p>Applications Sacubitril is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014)<br></p>Fórmula:C24H28NOCa2Cor e Forma:NeatPeso molecular:430.52Carfilzomib (2S,4R)-Diol
Produto Controlado<p>Applications Carfilzomib (2S,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Cor e Forma:NeatPeso molecular:737.93
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