Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2592 produtos de "Sulfonamidas e Derivados"
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rac Indapamide-d3
CAS:Produto Controlado<p>Applications Labelled Indapamide. Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Fórmula:C16H13D3ClN3O3SCor e Forma:White To Light Orange ColorPeso molecular:368.858-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Fórmula:C10H9NCor e Forma:Light Yellow LiquidPeso molecular:143.1854’-Hydroxyacetophenone Oxime
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C8H9NO2Cor e Forma:NeatPeso molecular:151.16Gliclazide-d4
CAS:Produto ControladoFórmula:C152H4H17N3O3SCor e Forma:White To Off-WhitePeso molecular:327.44Tosylurethane
CAS:Produto Controlado<p>Impurity Gliclazide EP Impurity C<br>Applications Tosylurethane (Gliclazide EP Impurity C) is an intermediate in the synthesis of Gliclazide (G409877), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>Fórmula:C10H13NO4SCor e Forma:Off WhitePeso molecular:243.284-Amino-6-chloro-1,3-benzenedisulfonamide
CAS:Produto Controlado<p>Impurity Hydrochlorothiazide EP Impurity B<br>Applications Diuretic. Hydrochlorothiazide EP Impurity B.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Joshi, S., et al.: J. Pharm. Biomed. Anal., 52, 362 (2010), Castillo-Garit, J., et al.: Eur. J. Pharm. Sci., 39, 30 (2010),<br></p>Fórmula:C6H8ClN3O4S2Cor e Forma:White To Light BrownPeso molecular:285.73Sulfacetamide-d4
CAS:Produto Controlado<p>Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Fórmula:C8H6D4N2O3SCor e Forma:NeatPeso molecular:218.27Acetaminophen-13C2, 15N1
CAS:Produto Controlado<p>Applications Acetaminophen-13C2, 15N1 is doubly labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C613C2H915NO2Cor e Forma:WhitePeso molecular:154.14Sulfamethoxazole β-D-Glucuronide
CAS:<p>Applications The main metabolite of Sulfamethoxazole.<br>References Altenburger, R., et al.: Environ. Toxicol. Chem., 19, 2341 (2000), Pascoe, R., et al.: Anal. Chem., 73, 6014 (2001), Zhaohua, H., et al.: Eur. J. Med. Chem., 36, 863 (2001),<br></p>Fórmula:C16H19N3O9SCor e Forma:NeatPeso molecular:429.40p-Butyl Ibuprofen (~90%)
CAS:Produto ControladoFórmula:C13H18O2Pureza:~90%Cor e Forma:NeatPeso molecular:206.28Ibuprofen Piconol
CAS:Produto Controlado<p>Applications Ibuprofen Piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen (I140000), which is a selective cyclooxygenase inhibitor.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); Xiang, L., et al.: Huaxi Yaoxue Zazhi, 21, 178 (2006); Chem. and Eng. News p9, July 4 (2016);<br></p>Fórmula:C19H23NO2Cor e Forma:NeatPeso molecular:297.394'-Isobutylacetophenone
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Fórmula:C12H16OCor e Forma:Colourless To Light YellowPeso molecular:176.25rac Indapamide
CAS:<p>Applications Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Fórmula:C16H16ClN3O3SCor e Forma:White To Off-WhitePeso molecular:365.833-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine
CAS:Produto Controlado<p>Applications An impurity of Sulfasalazine (S699084).<br></p>Fórmula:C29H22N6O7S2Cor e Forma:NeatPeso molecular:630.65rac Ibuprofen
CAS:Produto Controlado<p>Applications A selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has has been shown to reduce Ebola infection in rodents (4).This compound is a contaminant of emerging concern (CECs).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016);<br></p>Fórmula:C13H18O2Cor e Forma:NeatPeso molecular:206.28Ethyl 2-Bromoisovalerate
CAS:<p>Applications Ethyl 2-Bromoisovalerate (cas# 609-12-1) is a compound useful in organic synthesis.<br></p>Fórmula:C7H13BrO2Cor e Forma:NeatPeso molecular:209.08Indomethacin-d4
CAS:Produto Controlado<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C192H4H12ClNO4Cor e Forma:White To Off-WhitePeso molecular:361.81Brinzolamide
CAS:Produto Controlado<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Fórmula:C12H21N3O5S3Cor e Forma:NeatPeso molecular:383.51N-Hydroxy Sulfamethoxazole
CAS:Produto Controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H11N3O4SCor e Forma:NeatPeso molecular:269.282-(4-Chloro-3-sulfobenzoyl)-benzoic Acid
CAS:Produto Controlado<p>Applications 2-(4-Chloro-3-sulfobenzoyl)-benzoic Acid is an impurity of Chlorthalidone (C427500) which is used as a diuretic.<br>References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966); Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972); Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985)<br></p>Fórmula:C14H9ClO6SCor e Forma:NeatPeso molecular:340.74Phthalide
CAS:Produto Controlado<p>Applications Phthalide may be used in scaffolds for the design of high potency monoamine oxidase (MAO) inhibitors.<br>References Li, P.Z., et. al.: Med. Chem. Res., 23, 3624 (2014)<br></p>Fórmula:C8H6O2Cor e Forma:ColourlessPeso molecular:134.13(R)-(-)-Ibuprofen
CAS:Produto Controlado<p>Applications A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C13H18O2Cor e Forma:White SolidPeso molecular:206.282,4-Dichloro-5-sulfamoylbenzoic Acid
CAS:Produto Controlado<p>Impurity Furosemide EP Impurity B<br>Applications 2,4-Dichloro-5-sulfamoylbenzoic Acid is a chlorinated sulfamoylbenzoic acid with diuretic acid.<br>References Shani, J. et al.: Pharmacology, 26, 172 (1983); Lebedev, A.A. et al.: Khim.-Farm. Zhur., 19, 1205 (1985);<br></p>Fórmula:C7H5Cl2NO4SCor e Forma:WhitePeso molecular:270.09Hydroflumethiazide
CAS:Produto Controlado<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C8H8F3N3O4S2Cor e Forma:NeatPeso molecular:331.29Methiocarb Sulfone
CAS:<p>Applications Methiocarb Sulfone is a pesticide which is used in the protection of crops from insects and fungus.<br>References Wong, J. et al.: J. Agri,. Food. Chem., 58, 5897 (2010); Ghini, S. et al.: Arch. Env. Cont. Toxicol., 47, 479 (2004);<br></p>Fórmula:C11H15NO4SCor e Forma:Colourless SolidPeso molecular:257.31Furosemide-d5
CAS:Produto Controlado<p>Applications Labelled Furosemide (F865000). Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Fórmula:C12D5H6ClN2O5SCor e Forma:WhitePeso molecular:335.77Tetraethyleneglycol Bisibuprofen Ester
CAS:<p>Applications Tetraethyleneglycol Bisibuprofen Ester is an impurity of ibuprofen (rac, I140000) which is a selective cyclooxygenase inhibitor. It inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Fórmula:C34H50O7Cor e Forma:Colourless To Light BrownPeso molecular:570.7573-Chloro-2-methylaniline
CAS:Fórmula:C7H8ClNCor e Forma:Light Yellow To Light BrownPeso molecular:141.60Ibuprofen Sodium Salt Dihydrate
CAS:Produto ControladoFórmula:C13H17O2·2H2O·NaCor e Forma:NeatPeso molecular:264.293N-Acetyl Zonisamide
CAS:Produto Controlado<p>Applications A metabolite of Zonisamide (Z700000), a new anticonvulsant.<br>References Perchalski, R. J., et al.: J. Clin. Pharmacol., 26, 435 (1986), Stiff, D.D., et al.: Drug Metab. Disp., 18, 888 (1990),<br></p>Fórmula:C10H10N2O4SCor e Forma:NeatPeso molecular:254.26(R)-(-)-Ibuprofen-d3
CAS:Produto Controlado<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C13H15D3O2Cor e Forma:NeatPeso molecular:209.3N-(p-Toluenesulfonyl)urea
CAS:<p>Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.<br>References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);<br></p>Fórmula:C8H10N2O3SCor e Forma:NeatPeso molecular:214.242α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Fórmula:C12H18OCor e Forma:Colourless LiquidPeso molecular:178.27Trimethoprim-13C3
CAS:Produto Controlado<p>Applications Antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C3C11H18N4O3Cor e Forma:NeatPeso molecular:293.30N-Methylsulfonyl Nimesulide
CAS:<p>Impurity Nimesulide EP Impurity F<br>Applications N-Methylsulfonyl Nimesulide is an impurity of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),<br></p>Fórmula:C14H14N2O7S2Cor e Forma:NeatPeso molecular:386.40Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:<p>Stability Hygroscopic, Not stable in aqueous solutions.<br>Applications Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) (cas# 115075-59-7) is a compound useful in organic synthesis.<br></p>Fórmula:C19H26O8Cor e Forma:NeatPeso molecular:382.408-Desethyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity A<br>Applications 8-Desethyl Etodolac (Etodolac EP Impurity A) is an impurity of Etodolac (E933100) which was examined for mutagenicity in reverse mutation tests on bacteria. Etodolac impurity A.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>Fórmula:C15H17NO3Cor e Forma:NeatPeso molecular:259.30Glipizide
CAS:Produto Controlado<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)<br></p>Fórmula:C21H27N5O4SCor e Forma:WhitePeso molecular:445.54Metazachlor
CAS:Produto Controlado<p>Applications A chloroacetanilide herbicide used on vegetable crops.<br>References Matthies, M., et al.: Environ. Sci. Technol., 43, 9223 (2009); Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009); Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010); Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010);<br></p>Fórmula:C14H16ClN3OCor e Forma:Off White To Light BeigePeso molecular:277.752-Aminopyrimidine
CAS:<p>Applications 2-Aminopyrimidine is used in the synthesis of sulfonamides as isoform-selective inhibitors with efficacy in rodent pain models.<br>References Focken, T. et al.: ACS Med. Chem., 7, 277 (2016); Reddy, M. et al.: Bioorg. Med. Chem., 24, 521 (2016);<br></p>Fórmula:C4H5N3Cor e Forma:NeatPeso molecular:95.10N-Acetyl Sulfamethoxazole-d4 (major)
CAS:Produto ControladoFórmula:C122H4H9N3O4SCor e Forma:Light Orange Light BrownPeso molecular:299.34Diethyl Carbonate
CAS:Produto Controlado<p>Applications Diethyl Ester Carbonic Acid is used in the synthesis of 2-oxooxazolidines as antibacterials. Also used in the synthesis of donepezil/huperzine fragments as acetylcholinesterase inhbitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gregory, W. et al.: J. Med. Chem., 32, 1673 (1989); Bioorg. Med. Chem., 21, 676 (2013);<br></p>Fórmula:C5H10O3Cor e Forma:Colourless To Light YellowPeso molecular:118.034-(2-Methylpropyl)benzeneethanol
CAS:Produto ControladoFórmula:C12H18OCor e Forma:NeatPeso molecular:178.27Triclocarban-d4 (4-chlorophenyl-d4)
CAS:Produto Controlado<p>Applications Triclocarban-d4 (4-chlorophenyl-d4) (CAS# 1219799-29-7) is a useful isotopically labeled research compound.<br></p>Fórmula:C132H4H5Cl3N2OCor e Forma:Off-WhitePeso molecular:319.614-Acetylamino-2-chlorophenol
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C8H8ClNO2Cor e Forma:White To Light PurplePeso molecular:185.61O-Desmethyl Indomethacin
CAS:Produto Controlado<p>Applications The major metabolite of Indomethacin.<br>References Lewis, R., et al.: J. Clin. Invest., 53, 1607 (1974), Alvan, G., et al.: Clin. Pharmacol. Ther., 18, 364 (1975), Mungall, D., et al.: J. Pharm. Sci., 73, 1000 (1984), Baldwin, S., et al.: Xenobiotica, 25, 261 (1995),<br></p>Fórmula:C18H14ClNO4Cor e Forma:NeatPeso molecular:343.76N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Produto Controlado<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C16H16N2O4Cor e Forma:NeatPeso molecular:300.315-Amino-1,3,4-thiadiazole-2-thiol
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity G<br>Applications 5-Amino-1,3,4-thiadiazole-2-thiol is a thiadiazole derivative with antibacterial acitivity used in the preparation of herbicides as well as carbonic anhydrase inhibitors. (Acetazolamide EP Impurity G)<br>References Li, Z. et al.: Ying. Huax., 5, 54 (1988); Supuran, C. et al.: Rev. Roum. Chim., 40, 1227 (1995);<br></p>Fórmula:C2H3N3S2Cor e Forma:White To BeigePeso molecular:133.19Metribuzin DK
CAS:Produto Controlado<p>Applications Metribuzin DK is a selective triazine herbicide used in the control of broadleaf weeds. Used in the protection of vegetable and fruit crops. Pesticide.<br>References Xie, Y. et al.: Microchem. J., 133, 468 (2017);<br></p>Fórmula:C7H12N4O2Cor e Forma:NeatPeso molecular:184.202-[4-(2-Methylpropenyl)phenyl]propionic Acid
CAS:<p>Applications 2-[4-(2-Methylpropenyl)phenyl]propionic Acid is a byproduct of Ibuprofen (I140000(P)), which is an anti-inflammatory drug.<br>References Sharma, K., et al.: Int. J. Environ. Sci. Tech., 16, 8315 (2019)<br></p>Fórmula:C13H16O2Cor e Forma:Light YellowPeso molecular:204.262-Amino-4-methylamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
CAS:Produto ControladoFórmula:C15H20N4O3Cor e Forma:NeatPeso molecular:304.34Nicosulfuron-d6
CAS:Produto Controlado<p>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>Fórmula:C152H6H12N6O6SCor e Forma:NeatPeso molecular:416.44Saccharin-d4
CAS:Produto Controlado<p>Applications Labelled Saccharin (S080800). It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.<br>References Taylor, J.D., et al.: Food Cosmet. Toxicol., 6, 313 (1968), Arnold, D.L., et al.: Fundam. Appl. Toxicol., 4, 674 (1984), Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds<br></p>Fórmula:C72H4HNO3SCor e Forma:White To Off-WhitePeso molecular:187.21cis-Glimepiride
CAS:Produto Controlado<p>Impurity Glimepiride EP Impurity A<br>Applications cis-Glimepiride (Glimepiride EP Impurity A) is the cis-isomer of Glimepiride found in a bulk drug substance.<br>References Drummer, O., et al.: Anal. Toxicol., 17, 225 (1993), Magni, F., et al.: Anal. Biochem., 282, 136 (2000), Khan, M., et al.: J. Pharma. Biomed. Anal., 39, 928 (2005),<br></p>Fórmula:C24H34N4O5SCor e Forma:NeatPeso molecular:490.62Sulfadimethoxine
CAS:Produto Controlado<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965), Bohni, et al.: Chemotherapy, 14, 195 (1969),<br></p>Fórmula:C12H14N4O4SCor e Forma:Off-WhitePeso molecular:310.334-Hydroxy Triamterene
CAS:Produto Controlado<p>Applications A metabolite of Triamterne, a diuretic agent.<br>References Vollmer, G., et al.: Arzneim.-Forsch., 31, 529 (1981), Gilfrich, H.J., et al.: Eur. J. Clin. Pharmacol., 25, 237 (1983),<br></p>Fórmula:C12H11N7OCor e Forma:NeatPeso molecular:269.26trans-Hydroxy Glimepiride
CAS:Produto Controlado<p>Applications An active metabolite of Glimepiride.<br>References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Fórmula:C24H34N4O6SCor e Forma:NeatPeso molecular:506.625-Hydroxy Indapamide
CAS:Produto Controlado<p>Applications 5-Hydroxy Indapamide is a major metabolite of Indapamide (I500100), and possesses similar antihypertensive and diuretic properties.<br>References Slater, T., et al.: Biochem. J., 222, 1 (1984), Josephson, R., et al.: J. Biol. Chem., 266, 2354 (1991), Del Rio, M., et al.: Eur. J. Pharm., 250, 133 (1993), Calder, J., et al.: Eur. J. Pharma., 256, 185 (1994),<br></p>Fórmula:C16H16ClN3O4SCor e Forma:NeatPeso molecular:381.83Tetrahydro Furosemide
CAS:Produto Controlado<p>Impurity Furosemide EP Impurity F<br>Applications Tetrahydro Furosemide is used as a carbonic anhydrase inhibitor inhibiting human, bacterial and archaeal isozymes.<br>References Alterio, V. et al.: Bioorg. Med. Chem. Lett., 17, 4201 (2007);<br></p>Fórmula:C12H15ClN2O5SCor e Forma:White SolidPeso molecular:334.78Althiazide
CAS:<p>Applications Diuretic and antihypertensive.<br>References Twagirumukiza, M., et al.: Trop. Med. Int. Health, 15, 350 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Peters, R., et al.: Anal. Bioanal. Chem., 396, 2583 (2010),<br></p>Fórmula:C11H14ClN3O4S3Cor e Forma:NeatPeso molecular:383.894-Amino-N-(6-chloro-5-methoxypyrimidin-4-yl)benzenesulfonamide
CAS:Produto Controlado<p>Applications 4-Amino-N-(6-chloro-5-methoxypyrimidin-4-yl)benzenesulfonamide is an impurity in the synthesis of Sulfadoxine (S699070), used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Fórmula:C11H11ClN4O3SCor e Forma:NeatPeso molecular:314.748Tribenuron
CAS:Produto Controlado<p>Applications Tribenuron is an herbicide used in the protection of grains and produce crops.<br>References Nazari A. et al.: Int J. Agri. Crop Sci., 5, 449 (2013);<br></p>Fórmula:C14H15N5O6SCor e Forma:NeatPeso molecular:381.36Trimethoprim-d4 (Major)
CAS:Produto ControladoFórmula:C14D5H15N4O3Cor e Forma:NeatPeso molecular:297.364Triflusulfuron
CAS:Produto Controlado<p>Stability Unstable in Aqueous Solution<br>Applications Triflusulfuron is derived from Triflusulfuron-methyl (T782000), which is widely used sulfonylurea herbicide.<br>References Song, N., et al.: Huanjing Kexue, 33, 4400 (2012);<br></p>Fórmula:C16H17F3N6O6SCor e Forma:NeatPeso molecular:478.4Ibuprofen 2-Monoglyceride
CAS:Produto Controlado<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Ibuprofen Related Compound is an Ibuprofen (I400135) derived compound. Ibuprofen is a drug for the treatment of pains of different origins.<br>References Mueller, P., et al.: Arzneimittel-Forschung, 44, 840 (1994)<br></p>Fórmula:C16H24O4Cor e Forma:Off WhitePeso molecular:280.359rac 2-Hydroxy Ibuprofen-d6
CAS:Produto Controlado<p>Applications A human labelled metabolite of Ibuprofen.<br>References Bales, J., et al.: Clin. Chem., 31, 757 (1985), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Zwiener, C., et al.: Anal. Bioanal. Chem., 372, 569 ( 2002), de Bernardi, B., et al.: J. Clin. Oncol., 21, 1592 (2003),<br></p>Fórmula:C13H12D6O3Cor e Forma:NeatPeso molecular:228.32rac-Etodolac
CAS:Produto Controlado<p>Applications Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Etodolac is an anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C17H21NO3Cor e Forma:Off-WhitePeso molecular:287.35Tribenuron-methyl (~90%)
CAS:Fórmula:C15H17N5O6SPureza:~90%Cor e Forma:White To TanPeso molecular:395.39Saccharin
CAS:<p>Applications It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.<br>References Taylor, J.D., et al.: Food Cosmet. Toxicol., 6, 313 (1968), Arnold, D.L., et al.: Fundam. Appl. Toxicol., 4, 674 (1984),<br></p>Fórmula:C7H5NO3SCor e Forma:ColourlessPeso molecular:183.182,4,6-Triaminopyrimidine
CAS:Produto Controlado<p>Applications 2,4,6-Triaminopyrimidine is an organic cation used to block paracellular conductance pathways of several epithelia in the rat kidney, ultimately affecting sodium and potassium excretion.<br>References Bowman, R., et al.: J. Pharmacol. Exp. Ther., 206, 207 (1978); Rennick, B.: Renal Trans. Org. Subst., No vol. given, 178 (1981)<br></p>Fórmula:C4H7N5Cor e Forma:NeatPeso molecular:125.07Aceclofenac Benzyl Ester
CAS:Produto Controlado<p>Impurity Aceclofenac EP Impurity F<br>Applications A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent. Aceclofenac EP Impurity F.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C23H19Cl2NO4Cor e Forma:WhitePeso molecular:444.31Ibuprofen Sorbitol Ester (Mixture of Diastereomers)
Fórmula:C19H30O7Cor e Forma:NeatPeso molecular:740.87Furosemide Acyl-β -D-glucuronide
CAS:Produto Controlado<p>Applications A metabolite of Furosemide (F865000).<br></p>Fórmula:C18H19ClN2O11SCor e Forma:NeatPeso molecular:506.87Acetaminophen Dimer
CAS:<p>Applications Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986) (3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H16N2O4Cor e Forma:NeatPeso molecular:300.31(-)-Desethyl Methyl Etodolac
CAS:Produto Controlado<p>Impurity Etodolac EP Impurity C<br>Applications (-)-Desethyl Methyl Etodolac (Etodolac EP Impurity C) is an analog of Etodolac (E933100), a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2).Take not the R/S assignment is not determined.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C16H19NO3Cor e Forma:Off-White To Light YellowPeso molecular:273.33N-[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester
CAS:<p>Applications N-[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester, is an impurity of Glimepiride (G410150), which is a medium- to long-acting sulfonylurea antidiabetic drug.<br>References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993);<br></p>Fórmula:C18H23N3O6SCor e Forma:NeatPeso molecular:409.46α-Methyl-2-(2-methylpropyl)benzeneacetic Acid
CAS:Produto Controlado<p>Applications α-Methyl-2-(2-methylpropyl)benzeneacetic Acid is used in pharmaceutical analysis, and also a constituent of major drug tablets.<br>References Asmus, P.A., et al.: J. Chromatogr., 331, 169 (1985)<br></p>Fórmula:C13H18O2Cor e Forma:NeatPeso molecular:206.281a-Hydroxy Trimethoprim (Impurity)
CAS:Produto Controlado<p>Applications α-Hydroxy Trimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections.<br>References Dauber-Osguthorpe, P., et al.: Proteins, 4, 31, (1988); Darrell, J., et al.: J. Clin. Pathol., 21, 202 (1968); Zhanel, G., et al.: Antimicrob. Agents Ch., 44, 1089 (2000)<br></p>Fórmula:C14H18N4O4Cor e Forma:Off White SolidPeso molecular:306.32N-Nitroso rac Bendroflumethiazide
Produto ControladoFórmula:C15H13F3N4O5S2Cor e Forma:NeatPeso molecular:450.4134-O-Desmethyl 4-O-Ethyl Trimethoprim
CAS:<p>Applications 4-O-Desmethyl 4-O-Ethyl Trimethoprim is a derivative of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 4-O-Desmethyl 4-O-Ethyl Trimethoprim also has potential antibacterial activity.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981)<br></p>Fórmula:C15H20N4O3Cor e Forma:White SolidPeso molecular:304.34(S)-(+)-Ibuprofen
CAS:<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Fórmula:C13H18O2Pureza:99.51% - 99.86%Cor e Forma:Colourless Crystalline SolidPeso molecular:206.282,3-Dihydro-2-methyl-1H-indol-1-amine Hydrochloride
CAS:Produto Controlado<p>Applications 2,3-Dihydro-2-methyl-1H-indol-1-amine Hydrochloride is an synthetic intermediate of Indapamide (I500100), an antihypertensive agent and a diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Fórmula:C9H12N2·ClHCor e Forma:Light BrownPeso molecular:184.67Saluamine
CAS:Produto Controlado<p>Impurity Furosemide EP Impurity C<br>Applications A metabolite of Furosemide.<br>References Smith, D., et al.: Drug Metab. Disposit., 8, 337 (1980), Andreasen, F., et al.: Br. J. Clin. Pharmacol., 14, 306 (1982), Choi, Y., et al.: J. Pharm. Sci., 80, 638 (1991)<br></p>Fórmula:C7H7ClN2O4SCor e Forma:BeigePeso molecular:250.66N,3-Dimethylaniline
CAS:<p>Impurity Tolnaftate EP Impurity D<br>Applications N,3-Dimethylaniline (Tolnaftate EP Impurity D) is a Tolnaftate (T535400) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Erickson, R., et al.: Environ. Toxicol. Chem., 25, 1512 (2006), Kelly, B., et al.: Science, 317, 236 (2007),<br></p>Fórmula:C8H11NCor e Forma:NeatPeso molecular:121.181-Oxo Ibuprofen
CAS:<p>Impurity Ibuprofen EP Impurity J<br>Applications 1-Oxo Ibuprofen (Ibuprofen EP Impurity J), is a degradation product of Ibuprofen arising from oxidative and thermal treatments. 1-Oxo Ibuprofen is the Ibuprofen impurity J.<br>References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Vargas, F., et al.: Pharmazie, 11, 767 (1991), Lee, J., et al.: Pharm. Res., 9, S170 (1995),<br></p>Fórmula:C13H16O3Cor e Forma:White To Off-WhitePeso molecular:220.26N-1,3,4-Thiadiazol-2-ylacetamide
CAS:<p>Impurity Acetazolamide EP Impurity B<br>Applications N-1,3,4-Thiadiazol-2-ylacetamide is an impurity of Acetazolamide (A161500). Acetazolamide EP Impurity B<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H5N3OSCor e Forma:White To Off-WhitePeso molecular:143.17Vaborbactam
CAS:Produto Controlado<p>Applications Vaborbactam is a non-β-lactam β-lactamase inhibitor. While not effective as an antibiotic by itself, it restores potency to existing antibiotics by inhibiting the beta-lactamase enzymes that would otherwise degrade them. When combined with an appropriate antibiotic it can be used for the treatment of gram-negative bacterial.<br>References Hecker, S.J., et al.: Journal of Medicinal Chemistry, 58, 3682 (2015);<br></p>Fórmula:C12H16BNO5SCor e Forma:NeatPeso molecular:297.14Sulfadimethoxine-d6
CAS:Produto Controlado<p>Applications Sulfadimethoxine-d6 is deuterium labelled sulfadimethoxine-d6, which is an antibacterial.<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965); Bohni, et al.: Chemotherapy, 14, 195 (1969)<br></p>Fórmula:C122H6H8N4O4SCor e Forma:Colourless To Off-WhitePeso molecular:316.37Terizidone-15N2,d6 (Major)
CAS:Produto Controlado<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Fórmula:C14H8D6N215N2O4Pureza:>80%Cor e Forma:NeatPeso molecular:310.31Nitrobenzene
CAS:Produto Controlado<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>Fórmula:C6H5NO2Cor e Forma:Light YellowPeso molecular:123.11
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