GSK-3 inhibitor 3

CAS: 2227279-84-5

Ref. TM-T77342

Informação sobre produto

• Nome: GSK-3 inhibitor 3
• CAS: 2227279-84-5

Descrição

GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively.GSK-3 inhibitor 3 reduces the phosphorylation level of tau protein S396 with an IC50 of 10 nM in a triple transgenic mouse model of Alzheimer's disease. GSK-3 inhibitor 3 reduced the phosphorylation level of tau protein S396 in a triple transgenic mouse model of Alzheimer's disease, with an IC50 of 10 nM.GSK-3 inhibitor 3 can be used for the study of neurological diseases.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 410.4
• Fórmula: C₂₃H₁₅FN₆O
• Pureza: 98.36%
• Cor/forma: Soild