gsk-3
Os inibidores da GSK-3 são compostos que alvo a Glicogênio Sintase Quinase 3 (GSK-3), uma enzima envolvida em numerosos processos celulares, incluindo o metabolismo do glicogênio, a transcrição genética e a proliferação celular. A GSK-3 está implicada em várias doenças, como diabetes, distúrbios neurodegenerativos e câncer. Os inibidores da GSK-3 são ferramentas importantes para explorar essas vias e desenvolver potenciais terapias. Na CymitQuimica, oferecemos inibidores da GSK-3 para apoiar sua pesquisa em doenças metabólicas, neurobiologia e oncologia.
Foram encontrados 107 produtos para "gsk-3".
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BRD0705
CAS:BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Fórmula:C20H23N3OPureza:99.01%Cor e Forma:SolidPeso molecular:321.429-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Fórmula:C22H13FN2O5Pureza:99.28% - 99.32%Cor e Forma:SolidPeso molecular:404.35Ref: TM-T14066
1mg50,00€2mg66,00€5mg94,00€1mL*10mM (DMSO)110,00€10mg155,00€25mg309,00€50mg447,00€100mg667,00€Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Fórmula:C23H14Na2O11Pureza:99.4% - 99.95%Cor e Forma:White SolidPeso molecular:512.33Indazole
CAS:Indazole, a heterocyclic compound, offers diverse biological activities.Fórmula:C7H6N2Pureza:99.59% - 99.85%Cor e Forma:White SolidPeso molecular:118.1359Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultarPROTAC GSK-3β Degrader-1
PROTACGSK-3β Degrader-1 (compound 1) is a degrader targeting GSK-3β with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3β inhibitor), a PEG linker, and CRBN (E3 ligase ligand). It reduces neurotoxicity induced by Aβ25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.Fórmula:C43H42Cl2N6O9Cor e Forma:SolidPeso molecular:856.23903GSK3-IN-1
CAS:GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.Fórmula:C14H10ClN3OSPureza:99.99%Cor e Forma:SolidPeso molecular:303.767Ref: TM-T9987
2mg42,00€5mg60,00€1mL*10mM (DMSO)73,00€10mg100,00€25mg215,00€50mg318,00€100mg455,00€200mg617,00€GSK-3 Inhibitor 5
CAS:4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.Fórmula:C9H6BrNOPureza:99.9%Cor e Forma:SolidPeso molecular:224.054FRATide
CAS:FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.Fórmula:C55H102N2O2Cor e Forma:SolidPeso molecular:823.433Phospho-Glycogen Synthase Peptide-2(substrate)
CAS:Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Fórmula:C123H191N40O48PCor e Forma:SolidPeso molecular:3029.087GSK3β/mTOR modulator 1
GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.Fórmula:C19H28O5Cor e Forma:SolidPeso molecular:336.19367GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Fórmula:C15H12N4O2SCor e Forma:SolidPeso molecular:312.35CHIR-98023
CAS:CHIR-98023 is a bio-active chemical.Fórmula:C20H16Cl2N8O2Cor e Forma:SolidPeso molecular:471.30GSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Fórmula:C18H15N5O3Cor e Forma:SolidPeso molecular:349.35BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.Fórmula:C21H16N2O6Cor e Forma:SolidPeso molecular:392.36GSK-3β inhibitor 21
GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.Cor e Forma:Odour SolidMeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Fórmula:C17H12BrN3O2Pureza:99.64%Cor e Forma:SolidPeso molecular:370.2Ref: TM-T21966
1mg37,00€5mg71,00€1mL*10mM (DMSO)81,00€10mg111,00€25mg208,00€50mg335,00€100mg492,00€500mg1.071,00€2B-(SP)
CAS:Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)Fórmula:C71H123N26O29PPureza:98%Cor e Forma:SolidPeso molecular:1835.87GSK-3β inhibitor 1
CAS:GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.Fórmula:C14H10N2OPureza:99.40%Cor e Forma:SolidPeso molecular:222.24Ref: TM-T11467
1mg60,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg200,00€25mg356,00€50mg537,00€100mg737,00€200mg973,00€GSK3-IN-4
CAS:GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.Fórmula:C18H20N4OPureza:98.33%Cor e Forma:White SolidPeso molecular:308.38
