CAS 100-48-1

4-Cyanopyridine

Description:

4-Cyanopyridine is an organic compound characterized by a pyridine ring substituted with a cyano group at the 4-position. Its molecular formula is C6H4N2, and it has a molecular weight of approximately 104.11 g/mol. This compound appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is known for its polar nature, which contributes to its solubility in polar solvents such as water and alcohols. 4-Cyanopyridine is utilized in various applications, including as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It exhibits properties such as moderate toxicity and should be handled with care, as it can be harmful if ingested or inhaled. Additionally, it can participate in various chemical reactions, including nucleophilic substitutions and cycloadditions, making it a versatile intermediate in synthetic chemistry. Proper safety measures should be observed when working with this compound due to its potential health hazards.

Formula: C₆H₄N₂

InChI: InChI=1S/C6H4N2/c7-5-6-1-3-8-4-2-6/h1-4H

InChI key: InChIKey=GPHQHTOMRSGBNZ-UHFFFAOYSA-N

SMILES: C(#N)C=1C=CN=CC1

Synonyms:

• 4-Azabenzonitrile
• 4-Nitrilopyridine
• 4-Pyridinecarbonitrile
• 4-Pyridinenitrile
• 4-Pyridyl cyanide
• 4-Pyridylcarbonitrile
• 4-cyano Pyridine
• Isonicotinic acid nitrile
• Isonicotinonitril
• Isonicotinonitrile
• Isonicotinonitrilo
• Nsc 60681
• Pyridine, 4-Cyano-
• Pyridine-3-Carbonitrile
• Pyridine-4-carbonitrile
• γ-Cyanopyridine

4-Cyanopyridine

CAS: 100-48-1

Formula: C₆H₄N₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 104.11

Ref: 3B-C0457

4-Cyanopyridine, 98%

CAS: 100-48-1

4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the syn

Formula: C₆H₄N₂

Purity: 98%

Color and Shape: Colorless to white to cream to pale brown, Crystals or powder or crystalline powder or lumps or fused solid or solid

Molecular weight: 104.11

Ref: 02-A10286

4-Cyanopyridine

CAS: 100-48-1

Formula: C₆H₄N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 104.1094

Ref: IN-DA000067

4-Cyanopyridine

CAS: 100-48-1

4-Cyanopyridine

Formula: C₆H₄N₂

Purity: 98%

Color and Shape: white solid

Molecular weight: 104.11g/mol

Ref: 54-OR301182

Isoniazid EP Impurity C (Isonicotinonitrile)

CAS: 100-48-1

Formula: C₆H₄N₂

Molecular weight: 104.11

Ref: 4Z-I-229

4-Cyanopyridine

CAS: 100-48-1

4-Cyanopyridine is a pyridine derivative widely used in biochemical experiments and drug synthesis research.

Formula: C₆H₄N₂

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 104.11

Ref: TM-T67669

Pyridine-4-carbonitrile

Controlled Product

CAS: 100-48-1

Formula: C₆H₄N₂

Color and Shape: Neat

Molecular weight: 104.11

Ref: 86-MM0845.03

4-Cyanopyridine

Controlled Product

CAS: 100-48-1

Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.
References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)

Formula: C₆H₄N₂

Color and Shape: White

Molecular weight: 104.11

Ref: TR-C982225

4-Cyanopyridine

CAS: 100-48-1

4-Cyanopyridine is an organic compound with the chemical formula (CN)N. It is a white solid that is soluble in water and polar solvents. When exposed to hydrochloric acid, 4-cyanopyridine undergoes a reaction that converts it to picolinic acid. This reaction proceeds through a mechanism in which the nucleophilic hydroxyl group of 4-cyanopyridine attacks the protonated nitrogen atom of hydrochloric acid. The resulting intermediate then loses a proton and becomes picolinic acid. Kinetic data on this reaction has been obtained from UV-vis spectroscopy, X-ray diffraction, and mass spectrometry experiments. The crystal structures of the bound form of 4-cyanopyridine and its quinoline derivatives have also been determined by x-ray crystallography.

Formula: C₆H₄N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 104.11 g/mol

Ref: 3D-FC54870

4-Cyanopyridine

CAS: 100-48-1

Formula: C₆H₄N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 104.112

Ref: 10-F050349

4-Cyanopyridine-13C3

Controlled Product

CAS: 100-48-1

Formula: C₃C₃H₄N₂

Color and Shape: Neat

Molecular weight: 107.087

Ref: TR-C982227

Isoniazide EP Impurity C

CAS: 100-48-1

Formula: C₆H₄N₂

Molecular weight: 104.11

Ref: ST-EA-CP-I10008

4-Cyanopyridine

CAS: 100-48-1

Formula: C₆H₄N₂

Molecular weight: 104.11

Ref: ST-EA-CP-N98007