CAS 1000313-40-5

Formula: C25H48N2O5Si

InChI: InChI=1S/C25H48N2O5Si/c1-10-11-12-13-14-21(28)26-19(4)23(30)27-20(15-18(2)3)22(29)25(16-31-25)17-32-33(8,9)24(5,6)7/h18-20H,10-17H2,1-9H3,(H,26,28)(H,27,30)/t19-,20-,25-/m0/s1

InChI key: OHYPIFPQEYUPDQ-RLSLOFABSA-N

SMILES: CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@]1(CO1)CO[Si](C)(C)C(C)(C)C

UK-101

CAS: 1000313-40-5

UK-101

Formula: C₂₅H₄₈N₂O₅Si

Purity: 99%

Molecular weight: 484.74

Ref: 54-BUP01489

UK-101

CAS: 1000313-40-5

Ref: IN-DA024BSU

UK-101

CAS: 1000313-40-5

UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM

Formula: C₂₅H₄₈N₂O₅Si

Purity: 98.97% - 99.08%

Color and Shape: Solid

Molecular weight: 484.7445

Ref: TM-T13247