CAS 1000413-72-8

[(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-biphenylyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid

Description:

The chemical substance with the name "[(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-biphenylyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid" and CAS number "1000413-72-8" is a complex organic compound characterized by its multi-functional structure, which includes a benzofuran moiety, a biphenyl group, and a methylsulfonyl substituent. This compound is likely to exhibit specific stereochemistry due to the presence of chiral centers, influencing its biological activity and interactions. The presence of the acetic acid functional group suggests potential acidic properties, which may affect its solubility and reactivity in various environments. Additionally, the dimethyl and methoxy groups contribute to its lipophilicity, potentially enhancing its permeability through biological membranes. Such compounds are often investigated for their pharmacological properties, including anti-inflammatory or analgesic effects, making them of interest in medicinal chemistry. Overall, the structural complexity and functional groups present in this compound suggest a diverse range of potential applications in pharmaceutical research and development.

Formula: C₂₉H₃₂O₇S

Synonyms:

• Tak875
• 3-Benzofuranacetic acid, 6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-, (3S)-
• Tak-875

[(3S)-6-({3-[4-(3-methanesulfonylpropoxy)-2,6-dimethylphenyl]phenyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid

CAS: 1000413-72-8

Formula: C₂₉H₃₂O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 524.6252

Ref: IN-DA0000MM

Fasiglifam

CAS: 1000413-72-8

Fasiglifam

Purity: ≥98%

Molecular weight: 524.63g/mol

Ref: 54-BUP12251

(S)-2-(6-((2',6'-Dimethyl-4'-(3-(Methylsulfonyl)Propoxy)-[1,1'-Biphenyl]-3-Yl)Methoxy)-2,3-Dihydrobenzofuran-3-Yl)Acetic Acid

CAS: 1000413-72-8

(S)-2-(6-((2',6'-Dimethyl-4'-(3-(Methylsulfonyl)Propoxy)-[1,1'-Biphenyl]-3-Yl)Methoxy)-2,3-Dihydrobenzofuran-3-Yl)Acetic Acid

Purity: 98%

Molecular weight: 524.63g/mol

Ref: 54-OR1024348

Fasiglifam (TAK-875)

CAS: 1000413-72-8

Formula: C₂₉H₃₂O₇S

Color and Shape: White To Off-White Solid

Molecular weight: 524.63

Ref: 4Z-F-126001

Fasiglifam

CAS: 1000413-72-8

Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.

Formula: C₂₉H₃₂O₇S

Purity: 99.82% - 99.9%

Color and Shape: Solid

Molecular weight: 524.63

Ref: TM-T2351

Fasiglifam

CAS: 1000413-72-8

Purity: 98%

Molecular weight: 524.63

Ref: 10-F979016

TAK-875

CAS: 1000413-72-8

Applications TAK-876 is a selective G protein-coupled receptor 40 (GPR40) agonist (1,2). TAK-876 is a novel oral medication that has been developed to improve the secretion of insulin in a glucose-dependent manner, which has the potential to improve the control of blood sugar levels with a low risk of hypoglycemia.
References (1) Arak, T., et al.: Diabetes. Obesity. Metabolism., 14, 271 (2012) (2) Burant, C.F.,et al.: Lancet., 379, 1403 (2012)

Formula: C₂₉H₃₂O₇S

Color and Shape: Off White Solid

Molecular weight: 524.6252

Ref: TR-T004915

TAK 875

CAS: 1000413-72-8

Inhibits GPR40, a GPCR that is also known as free fatty acid receptor 1

Formula: C₂₉H₃₂O₇S

Purity: Min. 95%

Molecular weight: 524.63 g/mol

Ref: 3D-FT137724