CAS 1000599-06-3

4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5β,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-, , 4-methylbenzenesulfonate (1:1)

CAS: 1000599-06-3

Formula: C₃₁H₃₃Cl₂FN₄O₅S

Molecular weight: 663.5869

Ref: IN-DA0000S6

Tesevatinib tosylate

CAS: 1000599-06-3

Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.

Formula: C₃₁H₃₃Cl₂FN₄O₅S

Color and Shape: Solid

Molecular weight: 663.59

Ref: TM-T201865