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CAS 1000998-59-3

:

BMS-687453

Description:
BMS-687453, with the CAS number 1000998-59-3, is a chemical compound that has been studied primarily for its potential therapeutic applications, particularly in the field of oncology. It is classified as a small molecule inhibitor, specifically targeting certain pathways involved in cancer cell proliferation and survival. The compound exhibits selective inhibition of specific kinases, which are enzymes that play critical roles in various cellular processes, including signal transduction and cell division. BMS-687453 has shown promise in preclinical studies, demonstrating efficacy against certain cancer types by disrupting the signaling pathways that promote tumor growth. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its suitability for clinical use. Additionally, ongoing research aims to elucidate its safety profile and potential side effects, which are crucial for evaluating its therapeutic index. Overall, BMS-687453 represents a significant area of interest in drug development aimed at improving cancer treatment outcomes.
Formula:C22H21ClN2O6
InChI:InChI=1S/C22H21ClN2O6/c1-14-19(24-21(31-14)16-6-8-17(23)9-7-16)13-30-18-5-3-4-15(10-18)11-25(12-20(26)27)22(28)29-2/h3-10H,11-13H2,1-2H3,(H,26,27)
InChI key:UJIBXDMNCMEJAY-UHFFFAOYSA-N
SMILES:CC1=C(N=C(O1)C2=CC=C(C=C2)Cl)COC3=CC=CC(=C3)CN(CC(=O)O)C(=O)OC
Synonyms:
  • CS-1533
  • N-[[3-[[2-(4-Chlorophenyl)-5-methyl-4-oxazolyl]methoxy]phenyl]methyl]-N-(methoxycarbonyl)glycine
  • 2-[[3-[[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]phenyl]methyl-methoxycarbonylamino]acetic acid
  • BMS-687453
  • Glycine, N-[[3-[[2-(4-chlorophenyl)-5-methyl-4-oxazolyl]methoxy]phenyl]methyl]-N-(methoxycarbonyl)-
  • BMS-687453;BMS687453;BMS 687453
  • N-(3-{[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine
Found 7 products.