CAS 1001350-96-4

BMS-754807

Description:

BMS-754807 is a small molecule inhibitor primarily known for its role in targeting insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) signaling pathways. It has been investigated for its potential therapeutic applications in various cancers and metabolic disorders due to its ability to disrupt the IGF signaling axis, which is often implicated in tumor growth and survival. The compound exhibits a moderate to high affinity for its targets, leading to inhibition of downstream signaling pathways that promote cell proliferation and survival. BMS-754807 is typically characterized by its chemical structure, which includes specific functional groups that contribute to its biological activity. In preclinical studies, it has shown promise in reducing tumor growth in certain cancer models. However, like many investigational drugs, its safety and efficacy in humans are still under evaluation, and it may have associated side effects that need to be carefully monitored during clinical trials. Overall, BMS-754807 represents a significant area of research in targeted cancer therapies.

Formula: C₂₃subH₂₄subFN₉subO

Synonyms:

• (2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide

BMS-754807

CAS: 1001350-96-4

Formula: C₂₃H₂₄FN₉O

Purity: %

Color and Shape: Solid

Molecular weight: 461.4948

Ref: IN-DA008TEL

BMS-754807

CAS: 1001350-96-4

BMS-754807

Formula: C₂₃H₂₄FN₉O

Purity: ≥98%

Molecular weight: 461.49

Ref: 54-BUP03156

(S)-1-(4-((5-Cyclopropyl-1H-Pyrazol-3-Yl)Amino)Pyrrolo[2,1-F][1,2,4]Triazin-2-Yl)-N-(6-Fluoropyridin-3-Yl)-2-Methylpyrrolidine-2-Carboxamide

CAS: 1001350-96-4

(S)-1-(4-((5-Cyclopropyl-1H-Pyrazol-3-Yl)Amino)Pyrrolo[2,1-F][1,2,4]Triazin-2-Yl)-N-(6-Fluoropyridin-3-Yl)-2-Methylpyrrolidine-2-Carboxamide

Formula: C₂₃H₂₄FN₉O

Purity: >98%

Molecular weight: 461.49

Ref: 54-PC108736

BMS 754807

CAS: 1001350-96-4

Formula: C₂₃H₂₄FN₉O

Molecular weight: 461.51

Ref: 4Z-B-221001

BMS 754807

CAS: 1001350-96-4

A reversible inhibitor of IGF-1R kinase and insulin receptor. Has anti-growth effects in mesenchymal, epithelial and hematopoietic tumor types. Synergistic with other cytotoxic, hormonal and targeted anti-cancer therapy.

Formula: C₂₃H₂₄FN₉O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 461.49 g/mol

Ref: 3D-FB64960

BMS-754807

CAS: 1001350-96-4

BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.

Formula: C₂₃H₂₄FN₉O

Purity: 99.69% - 99.94%

Color and Shape: White Solid

Molecular weight: 461.49

Ref: TM-T2349