CAS 1002351-34-9

Formula: C14H15ClN6O

InChI: InChI=1S/C14H15ClN6O/c1-17-8-2-3-21(6-8)12-11-10(19-14(16)20-12)9-4-7(15)5-18-13(9)22-11/h4-5,8,17H,2-3,6H2,1H3,(H2,16,19,20)/t8-/m1/s1

InChI key: QCLILBHBGZEDKK-MRVPVSSYSA-N

SMILES: CN[C@@H]1CCN(C1)C2=NC(=NC3=C2OC4=C3C=C(C=N4)Cl)N

JNJ 40279486

CAS: 1002351-34-9

JNJ 40279486 is an innovative and highly selective antagonist of the histamine H4 receptor (histamine H4receptor), with a Ki of 9 nM. It is a potential candidate for research in immune-driven inflammatory diseases.

Formula: C₁₄H₁₅ClN₆O

Molecular weight: 318.77

Ref: TM-T214340