CAS 1003000-59-6

NY0116

Formula: C₂₂H₂₃N₃O

InChI: InChI=1S/C22H23N3O/c23-21(24)25-16-17-26-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H4,23,24,25)

InChI key: FZXFGYLHTRBHNJ-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCN=C(N)N

Synonyms:

• Guanidine, N-[2-(triphenylmethoxy)ethyl]-
• NY0116

NY0116

CAS: 1003000-59-6

NY0116 is an agonist of the neuromedin U receptor 2 (NMUR2), exhibiting EC50 values of 27.76 μM for hNMUR1 and 13.61 μM for hNMUR2. In NMUR2 stably expressing HEK293 cells, NY0116 reduces cAMP levels while enhancing calcium signaling [1].

Formula: C₂₂H₂₃N₃O

Color and Shape: Solid

Molecular weight: 345.44

Ref: TM-T87049