CAS 100324-81-0: Lisofylline

Description: Lisofylline, with the CAS number 100324-81-0, is a synthetic compound that belongs to the class of xanthine derivatives. It is primarily recognized for its potential therapeutic applications, particularly in the treatment of conditions related to impaired blood flow and inflammation. Lisofylline exhibits properties that may enhance microcirculation and has been studied for its effects on various cellular processes, including anti-inflammatory and immunomodulatory activities. The compound is characterized by its ability to inhibit phosphodiesterase, leading to increased levels of cyclic AMP, which plays a crucial role in various physiological responses. Additionally, Lisofylline has been investigated for its potential neuroprotective effects and its role in promoting tissue repair. Its pharmacological profile suggests a multifaceted mechanism of action, making it a subject of interest in both clinical and research settings. However, further studies are necessary to fully elucidate its efficacy and safety in various therapeutic contexts.

Formula: C₁₃H₂₀N₄O₃

InChI: InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m1/s1

InChI key: InChIKey=NSMXQKNUPPXBRG-SECBINFHSA-N

SMILES: O=C1C2=C(N=CN2C)N(C(=O)N1CCCCC(O)C)C

Synonyms:

• (R)-1-(5-Hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione
• (R)-Lisofylline
• (R)-Lisophylline
• 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-, (R)-
• 1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-
• 3,7-Dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-1H-purine-2,6-dione
• Ct 1501R
• Lisofylline
• Lisophylline
• ProTec

1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-

CAS: 100324-81-0

• Formula: C₁₃H₂₀N₄O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 280.3229

(R)-Lisofylline

CAS: 100324-81-0

(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM).

• Formula: C₁₃H₂₀N₄O₃
• Purity: 99.50%
• Color and Shape: Solid
• Molecular weight: 280.32

(R)-Lisofylline

CAS: 100324-81-0

Applications A major metabolite of Pentoxifylline. Methylxanthine that inhibits production of phosphatidic acid during the …

• Formula: C₁₃H₂₀N₄O₃
• Color and Shape: Neat
• Molecular weight: 280.32

(R)-Lisofylline

CAS: 100324-81-0

Metabolite of pentoxifylline

• Formula: C₁₃H₂₀N₄O₃
• Purity: Min. 95%
• Molecular weight: 280.32 g/mol