STAT

Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.

Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.

UC-514321 directly targets STAT3/5 and represses TET1 expression.

Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants.

Nifuroxazide (Diarlidan), an oral nitrofuran antidiarrheal, blocks STAT1/3/5 activation.

Niclosamide olamine (Niclosamide Ethanolamine salt) is an Repellent, Insect Attractant and Chemosterilant.

STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 …

Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an …

L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking …

Golotimod HCl enhances antituberculosis therapy, boosts immune cells, and improves macrophage function.

Golotimod (TFA), an immunomodulating peptide, boosts antituberculosis treatments and enhances immune cell growth and macrophage …

(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM).

MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.

HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, …

NSC 370284 inhibits STAT3/5, reducing AML cell viability with TET1 overexpression in vitro/in vivo.

Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.

W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis, effectively halting cancer progression in subcutaneous …

Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some …

Eupalinolide K is a natural product

TLC1566-0618 shows antitumor activity and targets stat.