CAS 10047-33-3
:gastrin I
Description:
Gastrin I is a peptide hormone primarily involved in the regulation of gastric acid secretion in the stomach. It is produced by G cells in the gastric mucosa and plays a crucial role in digestive processes. Gastrin I is characterized by its structure, which consists of a chain of amino acids, typically containing 17 amino acids in its sequence. This hormone stimulates the parietal cells of the stomach to secrete hydrochloric acid, thereby aiding in digestion and maintaining an acidic environment necessary for enzyme activity. Additionally, gastrin I promotes gastric motility and influences the growth of the gastric mucosa. Its secretion is stimulated by the presence of food in the stomach, particularly proteins, and is regulated by various factors, including neural and hormonal signals. Abnormal levels of gastrin can be associated with gastrointestinal disorders, such as Zollinger-Ellison syndrome or peptic ulcers. Overall, gastrin I is essential for normal digestive function and maintaining the homeostasis of the gastrointestinal tract.
Formula:C97H124N20O31S
InChI:InChI=1/C97H124N20O31S/c1-49(2)39-68(114-95(146)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(148)73-19-12-37-117(73)76(121)48-102-85(136)60-24-30-74(119)104-60)93(144)110-65(29-35-81(130)131)91(142)109-64(28-34-80(128)129)90(141)108-63(27-33-79(126)127)89(140)107-62(26-32-78(124)125)88(139)106-61(25-31-77(122)123)87(138)103-50(3)84(135)113-69(41-52-20-22-55(118)23-21-52)86(137)101-47-75(120)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(145)111-66(36-38-149-4)92(143)115-72(44-82(132)133)96(147)112-67(83(98)134)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100,118H,12,19,24-44,47-48H2,1-4H3,(H2,98,134)(H,101,137)(H,102,136)(H,103,138)(H,104,119)(H,105,120)(H,106,139)(H,107,140)(H,108,141)(H,109,142)(H,110,144)(H,111,145)(H,112,147)(H,113,135)(H,114,146)(H,115,143)(H,116,148)(H,122,123)(H,124,125)(H,126,127)(H,128,129)(H,130,131)(H,132,133)
InChI key:GKDWRERMBNGKCZ-RNXBIMIWSA-N
SMILES:CC(C)CC(C(=NC(CCC(=O)O)C(=NC(CCC(=O)O)C(=NC(CCC(=O)O)C(=NC(CCC(=O)O)C(=NC(CCC(=O)O)C(=NC(C)C(=NC(Cc1ccc(cc1)O)C(=NCC(=NC(Cc1c[nH]c2ccccc12)C(=NC(CCSC)C(=NC(CC(=O)O)C(=NC(Cc1ccccc1)C(=N)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(Cc1c[nH]c2ccccc12)N=C(C1CCCN1C(=O)CN=C(C1CCC(=N1)O)O)O)O
Synonyms:- Gastrin I human
- Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
- Mucin Type Ii
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Gastrin I (human)
CAS:Bachem ID: 4030646.
Formula:C97H124N20O31SPurity:98.0%Color and Shape:WhiteMolecular weight:2098.23Gastrin I, human
CAS:Gastrin I, human (Gastrin I (human)) is an endogenous peptide produced in the stomach that increases pepsinogen and acid secretion via the CCK2 receptor in theFormula:C97H124N20O31SPurity:98.62%Color and Shape:SolidMolecular weight:2098.2Gastrin I (Human)
CAS:Gastrin I is a peptide hormone that is used as a research tool to study the role of gastrin on different types of cells. It is also used to investigate the effects of this peptide on ion channels and protein interactions. Gastrin I has been shown to be an inhibitor of gastrin, which may be due to its ability to inhibit the production of pro-gastrin by blocking the activation of G cells.Formula:C97H124N20O31SPurity:Min. 95%Molecular weight:2,098.2 g/mol
