CAS 1005-39-6

2-(Methylthio)-4,6-pyrimidinediamine

Description:

2-(Methylthio)-4,6-pyrimidinediamine, with the CAS number 1005-39-6, is a chemical compound characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. This compound features a methylthio group (-S-CH3) attached to the pyrimidine ring, contributing to its unique properties. It is a diamine, indicating the presence of two amine functional groups (-NH2) at the 4 and 6 positions of the pyrimidine ring. This structure imparts specific reactivity, making it useful in various chemical syntheses and applications, particularly in pharmaceuticals and agrochemicals. The presence of the methylthio group can enhance the compound's solubility and influence its biological activity. Additionally, 2-(Methylthio)-4,6-pyrimidinediamine may exhibit properties such as moderate stability under standard conditions, and it may be sensitive to moisture and light. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₅H₈N₄S

InChI: InChI=1S/C5H8N4S/c1-10-5-8-3(6)2-4(7)9-5/h2H,1H3,(H4,6,7,8,9)

InChI key: InChIKey=AHAIUNAIAHSWPG-UHFFFAOYSA-N

SMILES: S(C)C=1N=C(N)C=C(N)N1

Synonyms:

• 2-(Methylsulfanyl)Pyrimidine-4,6-Diamine
• 2-(Methylthio)-4,6-pyrimidinediamine
• 2-(Methylthio)Pyrimidine-4,6-Diamine
• 2-Methylsulfanylpyrimidine-4,6-diamine
• 2-Methylthio-4,6-diaminopyrimidine
• 2-Methylthiopyrimidine-4,6-diamine
• 4,6-Diamino-2-(methylmercapto)pyrimidine
• 4,6-Diamino-2-(methylthio)pyrimidine
• 4,6-Pyrimidinediamine, 2-(methylthio)-
• NSC 44919
• NSC 60555

4,6-Diamino-2-(methylthio)pyrimidine, 97%

CAS: 1005-39-6

4,6-Diamino-2-(methylthio)pyrimidine can reacts with 3-Ethoxy-acrylic acid ethyl ester to get 4-Amino-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information ma

Formula: C₅H₈N₄S

Purity: 97%

Color and Shape: White to cream or yellow, Powder

Molecular weight: 156.21

Ref: 02-L07888

4,6-Pyrimidinediamine, 2-(methylthio)-

CAS: 1005-39-6

Formula: C₅H₈N₄S

Purity: 96%

Color and Shape: Solid

Molecular weight: 156.2088

Ref: IN-DA00025M

2-(Methylthio)pyrimidine-4,6-diamine

CAS: 1005-39-6

2-(Methylthio)pyrimidine-4,6-diamine

Purity: 98%

Molecular weight: 156.21g/mol

Ref: 54-OR80325

2-Methylthiopyrimidine-4,6-diamine

CAS: 1005-39-6

2-Methylthiopyrimidine-4,6-diamine is a potent inhibitor of the enzyme DNA polymerase. It has shown to be effective against hepg2 cells and other cancer cells. The compound binds covalently to the active site of the enzyme, where it stabilizes the transition state and deshields the electrostatic field around the nucleophilic nitrogen atom. This interaction leads to a decreased affinity for ATP, which is required for DNA synthesis. 2-Methylthiopyrimidine-4,6-diamine also has antimalarial activity and inhibits amide bond formation in hepg2 cells.

Formula: C₅H₈N₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 156.21 g/mol

Ref: 3D-FM35226

4,6-Diamino-2-methylmercaptopyrimidine

CAS: 1005-39-6

Formula: C₅H₈N₄S

Purity: 96%

Color and Shape: Solid, No data available.

Molecular weight: 156.21

Ref: 10-F044414