CAS 1005780-62-0

TAK-593

CAS: 1005780-62-0

TAK-593

Formula: C₂₃H₂₃N₇O₃

Purity: ≥98%

Molecular weight: 445.47

Ref: 54-BUP09817

TAK-593

CAS: 1005780-62-0

TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).

Formula: C₂₃H₂₃N₇O₃

Purity: 99.37%

Color and Shape: Solid

Molecular weight: 445.47

Ref: TM-T16975

TAK-593

CAS: 1005780-62-0

TAK-593 is an activator of the N-terminal signaling domain of the erythropoietin receptor that is selective for the erythropoietin receptor. It inhibits tumor growth and induces apoptosis in cancer cells by inhibiting protein synthesis. TAK-593 has been shown to induce tumor regression in mice with lung carcinomas, prostate carcinomas, and breast carcinomas. It also prevents the development of retinal neovascularization in a rat model of oxygen-induced retinopathy and reduces intraocular pressure in rats with experimental glaucoma. TAK-593 is a potent inhibitor of angiogenesis and vascular permeability.

Formula: C₂₃H₂₃N₇O₃

Purity: Min. 95%

Molecular weight: 445.47 g/mol

Ref: 3D-FQB78062