CAS 1006-50-4
:Quinoline, 5-iodo-
Description:
Quinoline, 5-iodo- is an organic compound characterized by its fused bicyclic structure, which consists of a benzene ring fused to a pyridine ring. The presence of an iodine atom at the 5-position of the quinoline structure significantly influences its chemical properties and reactivity. This compound is typically a pale yellow to brown liquid or solid, depending on its purity and specific conditions. Quinoline derivatives, including 5-iodo-quinoline, are known for their applications in medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. The iodine substituent can enhance the compound's reactivity in electrophilic substitution reactions and can also serve as a useful handle for further chemical modifications. Additionally, quinoline derivatives are often studied for their biological activities, including antimicrobial and antimalarial properties. As with many halogenated compounds, safety precautions should be taken when handling 5-iodo-quinoline due to potential toxicity and environmental concerns.
Formula:C9H6IN
InChI:InChI=1S/C9H6IN/c10-8-4-1-5-9-7(8)3-2-6-11-9/h1-6H
InChI key:InChIKey=QUSDYFSFXQORKN-UHFFFAOYSA-N
SMILES:IC=1C2=C(C=CC1)N=CC=C2
Synonyms:- 5-Iodo-Quinoline
- 5-Iodoquinoline
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5-Iodoquinoline
CAS:5-Iodoquinoline is a serotonin transporter inhibitor that has been shown to have antidepressant properties. The compound competes with serotonin for transport and prevents it from binding to the receptor, which leads to an increase in extracellular serotonin. This active form has been synthesized by the reaction of 5-iodotriphenylenes with cyclobutanones. The pharmacological activity of 5-iodoquinoline was studied in vivo and proved that this drug may be useful for the treatment of depression.
Formula:C9H6INPurity:Min. 95%Molecular weight:255.05 g/mol
