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desloratadine

CAS 100643-71-8: desloratadine

Description:Desloratadine is a second-generation antihistamine primarily used to alleviate allergy symptoms such as sneezing, runny nose, and itchy eyes. It is a metabolite of loratadine and functions as a selective antagonist of peripheral H1 receptors, which helps reduce allergic responses without causing significant sedation, a common side effect of first-generation antihistamines. Desloratadine is characterized by its high oral bioavailability and long half-life, allowing for once-daily dosing. It is typically administered in the form of tablets or syrup and is well-tolerated, with a low incidence of adverse effects. The chemical structure of desloratadine includes a piperidine ring, contributing to its pharmacological properties. It is also known for its minimal interaction with the central nervous system, making it a preferred choice for individuals who need to avoid drowsiness. Overall, desloratadine is an effective and safe option for managing allergic conditions.

Formula:C19H19ClN2

InChI:InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2

InChI key:InChIKey=JAUOIFJMECXRGI-UHFFFAOYSA-N

SMILES:ClC=1C=CC2=C(C1)CCC=3C=CC=NC3C2=C4CCNCC4

  • Synonyms:
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
  • 8-Chloro-11-(4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • Aerius
  • Allex
  • Azomyr
  • Clarinex
  • Dasselta
  • Delopedil
  • See more synonyms
  • Descarboethoxyloratadine
  • Descarboethoxyloratidine
  • Desler
  • Eurodesa
  • NSC 675447
  • Neoclarityn
  • Opulis
  • Sch 34117
  • Sedno
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BrandProduct dataPurityPrice rangeEstimated delivery
EDQM - European Pharmacopoeia logo
Desloratadine CRS
REF: 41-Y0001584
CAS: 100643-71-8
- - -115.00 €Fri 02 May 25
British Pharmacopoeia logo
Loratadine impurity standard
REF: 47-875
CAS:
- - -211.00 €Fri 02 May 25
EDQM - European Pharmacopoeia logo
Desloratadine for system suitability CRS
REF: 41-Y0001582
CAS: 100643-71-8
- - -115.00 €Fri 02 May 25
USP logo
Desloratadine
REF: 45-1173042
CAS: 100643-71-8
- - -463.00 €Mon 05 May 25
USP logo
Loratadine Related Compound A (8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)
REF: 45-1370280
CAS: 100643-71-8
- - -1,371.00 €Mon 05 May 25
Indagoo logo
5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
REF: IN-DA0002K9
CAS: 100643-71-8
98%To inquireTue 06 May 25
Apollo Scientific logo
Desloratadine
REF: 54-OR1030381
CAS: 100643-71-8
98%32.00 €~1,444.00 €Mon 05 May 25
TLC logo
Loratadine EP Impurity D (Loratadine USP Related Compound A, Rupatadine EP Impurity B, Desloratadine)
REF: 4Z-L-102
CAS: 100643-71-8
- - -300.00 €~1,237.00 €Mon 05 May 25
Apollo Scientific logo
Desloratadine
REF: 54-BUP15799
CAS: 100643-71-8
≥98%79.00 €~544.00 €Mon 05 May 25
Glentham logo
Desloratadine
REF: 7W-GP6329
CAS: 100643-71-8
- - -To inquireMon 05 May 25
Cluzeau logo
Desloratadine-d4 (piperidinylidene-3,3,5,5-d4)(Desloratadine)
REF: 3U-D7532
CAS:
99 atom % D946.00 €~1,573.00 €Tue 06 May 25
Mikromol logo
8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Descarboethoxyloratadine; Desloratadine)
REF: 86-MM0257.01-0250
CAS: 100643-71-8
- - -2,440.00 €Wed 07 May 25
Doctor Ehrenstorfer logo
Desloratadine
REF: 04-C12157000
CAS: 100643-71-8
- - -126.00 €Wed 07 May 25
TCI logo
Desloratadine
REF: 3B-D3787
CAS: 100643-71-8
>98.0%(T)(HPLC)54.00 €~314.00 €Wed 07 May 25
Fluorochem logo
8-chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
REF: 10-F375848
CAS: 100643-71-8
99.00%24.00 €~250.00 €Wed 07 May 25
Acros logo
Desloratadine
REF: AC-46292
CAS: 100643-71-8
- - -170.00 €Wed 07 May 25
Targetmol logo
Desloratadine
REF: TM-T2520
CAS: 100643-71-8
100% - 99.79%42.00 €~364.00 €Tue 13 May 25
TLC logo
Latamoxef Impurity 48
REF: 4Z-L-102049
CAS:
- - -To inquireTue 13 May 25
TLC logo
Latamoxef Impurity 31
REF: 4Z-L-102032
CAS:
- - -To inquireTue 13 May 25
TRC logo
Desloratadine
REF: TR-D290250
CAS: 100643-71-8
- - -99.00 €~152.00 €Wed 14 May 25
discount label

Ref: 41-Y0001584

100mg115.00 €
Estimated delivery in United States, on Friday 2 May 2025
discount label

Ref: 47-875

25mg211.00 €
Estimated delivery in United States, on Friday 2 May 2025
discount label

Ref: 41-Y0001582

5mg115.00 €
Estimated delivery in United States, on Friday 2 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 45-1173042

200mg463.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Loratadine Related Compound A (8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)

CAS:100643-71-8

Ref: 45-1370280

15mg1,371.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Ref: IN-DA0002K9

1g25.00 €
5g36.00 €
10g55.00 €
1kgTo inquire
25g96.00 €
100g172.00 €
250g509.00 €
500g599.00 €
Estimated delivery in United States, on Tuesday 6 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 54-OR1030381

1g36.00 €
5g45.00 €
25g99.00 €
100g348.00 €
500g1,444.00 €
250mg32.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Ref: 4Z-L-102

5mg300.00 €
10mg477.00 €
25mg681.00 €
50mg885.00 €
100mg1,237.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 54-BUP15799

1g544.00 €
50mg79.00 €
100mg103.00 €
200mg163.00 €
500mg348.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 7W-GP6329

Undefined sizeTo inquire
Estimated delivery in United States, on Monday 5 May 2025
discount label

Ref: 3U-D7532

5mg946.00 €
10mg1,573.00 €
Estimated delivery in United States, on Tuesday 6 May 2025
discount label

Ref: 86-MM0257.01-0250

250mg2,440.00 €
Estimated delivery in United States, on Wednesday 7 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 04-C12157000

25mg126.00 €
Estimated delivery in United States, on Wednesday 7 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: 3B-D3787

1g314.00 €
100mg54.00 €
Estimated delivery in United States, on Wednesday 7 May 2025
discount label

Ref: 10-F375848

1g24.00 €
5g24.00 €
10g40.00 €
25g83.00 €
100g250.00 €
Estimated delivery in United States, on Wednesday 7 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: AC-46292

1g170.00 €
Estimated delivery in United States, on Wednesday 7 May 2025
discount label

Desloratadine

CAS:100643-71-8

Ref: TM-T2520

1g364.00 €
25mg42.00 €
50mg50.00 €
100mg69.00 €
200mg99.00 €
500mg229.00 €
1mL*10mM (DMSO)57.00 €
Estimated delivery in United States, on Tuesday 13 May 2025
discount label

Ref: 4Z-L-102049

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Tuesday 13 May 2025
discount label

Latamoxef Impurity 31

CAS:100643-71-8432543-89-0

Ref: 4Z-L-102032

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Tuesday 13 May 2025
discount label

Desloratadine

Controlled Product
CAS:100643-71-8

Ref: TR-D290250

10mg99.00 €
50mg116.00 €
100mg152.00 €
Estimated delivery in United States, on Wednesday 14 May 2025
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