CAS 100643-71-8: desloratadine
Description:Desloratadine is a second-generation antihistamine primarily used to alleviate allergy symptoms such as sneezing, runny nose, and itchy eyes. It is a metabolite of loratadine and functions as a selective antagonist of peripheral H1 receptors, which helps reduce allergic responses without causing significant sedation, a common side effect of first-generation antihistamines. Desloratadine is characterized by its high oral bioavailability and long half-life, allowing for once-daily dosing. It is typically administered in the form of tablets or syrup and is well-tolerated, with a low incidence of adverse effects. The chemical structure of desloratadine includes a piperidine ring, contributing to its pharmacological properties. It is also known for its minimal interaction with the central nervous system, making it a preferred choice for individuals who need to avoid drowsiness. Overall, desloratadine is an effective and safe option for managing allergic conditions.
Formula:C19H19ClN2
InChI:InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI key:InChIKey=JAUOIFJMECXRGI-UHFFFAOYSA-N
SMILES:ClC=1C=CC2=C(C1)CCC=3C=CC=NC3C2=C4CCNCC4
- Synonyms:
- 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
- 8-Chloro-11-(4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- Aerius
- Allex
- Azomyr
- Clarinex
- Dasselta
- Delopedil
- See more synonyms
- Descarboethoxyloratadine
- Descarboethoxyloratidine
- Desler
- Eurodesa
- NSC 675447
- Neoclarityn
- Opulis
- Sch 34117
- Sedno

Ref: 41-Y0001584
100mg | 115.00 € |

Ref: 47-875
25mg | 211.00 € |

Ref: 41-Y0001582
5mg | 115.00 € |

Desloratadine
Ref: 45-1173042
200mg | 463.00 € |

Loratadine Related Compound A (8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)
Ref: 45-1370280
15mg | 1,371.00 € |

5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
Ref: IN-DA0002K9
1g | 25.00 € | ||
5g | 36.00 € | ||
10g | 55.00 € | ||
1kg | To inquire | ||
25g | 96.00 € | ||
100g | 172.00 € | ||
250g | 509.00 € | ||
500g | 599.00 € |

Ref: 54-OR1030381
1g | 36.00 € | ||
5g | 45.00 € | ||
25g | 99.00 € | ||
100g | 348.00 € | ||
500g | 1,444.00 € | ||
250mg | 32.00 € |

Loratadine EP Impurity D (Loratadine USP Related Compound A, Rupatadine EP Impurity B, Desloratadine)
Ref: 4Z-L-102
5mg | 300.00 € | ||
10mg | 477.00 € | ||
25mg | 681.00 € | ||
50mg | 885.00 € | ||
100mg | 1,237.00 € |

Ref: 54-BUP15799
1g | 544.00 € | ||
50mg | 79.00 € | ||
100mg | 103.00 € | ||
200mg | 163.00 € | ||
500mg | 348.00 € |

Ref: 7W-GP6329
Undefined size | To inquire |

Desloratadine-d4 (piperidinylidene-3,3,5,5-d4)(Desloratadine)
Ref: 3U-D7532
5mg | 946.00 € | ||
10mg | 1,573.00 € |

8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Descarboethoxyloratadine; Desloratadine)
Ref: 86-MM0257.01-0250
250mg | 2,440.00 € |

Ref: 04-C12157000
25mg | 126.00 € |

Desloratadine
Ref: 3B-D3787
1g | 314.00 € | ||
100mg | 54.00 € |

8-chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Ref: 10-F375848
1g | 24.00 € | ||
5g | 24.00 € | ||
10g | 40.00 € | ||
25g | 83.00 € | ||
100g | 250.00 € |

Desloratadine
Ref: AC-46292
1g | 170.00 € |

Desloratadine
Ref: TM-T2520
1g | 364.00 € | ||
25mg | 42.00 € | ||
50mg | 50.00 € | ||
100mg | 69.00 € | ||
200mg | 99.00 € | ||
500mg | 229.00 € | ||
1mL*10mM (DMSO) | 57.00 € |

Ref: 4Z-L-102049
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Ref: 4Z-L-102032
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Desloratadine
Controlled ProductRef: TR-D290250
10mg | 99.00 € | ||
50mg | 116.00 € | ||
100mg | 152.00 € |