CAS 100678-32-8

cibenzoline succinate

Description:

Cibenzoline succinate, identified by its CAS number 100678-32-8, is a pharmaceutical compound primarily used for its antiarrhythmic properties. It is a derivative of cibenzoline, which is known for its ability to stabilize cardiac membranes and modulate ion channel activity, particularly sodium channels. This compound is typically presented as a white to off-white crystalline powder, indicating its solid-state at room temperature. Cibenzoline succinate is soluble in water and various organic solvents, which facilitates its formulation in different pharmaceutical preparations. Its mechanism of action involves the inhibition of abnormal electrical activity in the heart, making it useful in treating certain types of cardiac arrhythmias. Additionally, it may exhibit a favorable pharmacokinetic profile, allowing for effective dosing regimens. As with many pharmaceutical compounds, safety and efficacy are evaluated through clinical studies, and potential side effects may include cardiovascular and neurological impacts. Overall, cibenzoline succinate represents a significant compound in the field of cardiology, contributing to the management of heart rhythm disorders.

Formula: C₂₂H₂₄N₂O₄

InChI: InChI=1/C18H18N2.C4H6O4/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17;5-3(6)1-2-4(7)8/h1-10,16H,11-13H2,(H,19,20);1-2H2,(H,5,6)(H,7,8)

InChI key: InChIKey=XFUIOIWYMHEPIE-UHFFFAOYSA-N

SMILES: C1(C(C1)C=2NCCN2)(C3=CC=CC=C3)C4=CC=CC=C4.C(CC(O)=O)C(O)=O

Synonyms:

• (±)-2-(2,2-Diphenylcyclopropyl)-2-imidazoline Succinate (1:1)
• (±)-2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole Butanedioate (1:1)
• 1H-Imidazole, 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-, succinate (2:1)
• 1H-imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-, butanedioate (1:1)
• 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate
• 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate (1:1)
• Butanedioic acid, compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:1)
• Cibenol
• Cibenzoline succinate (1:1)
• Cifenline succinate
• Cipralan
• Exacor
• Ro 22-7796/001
• 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate
• (+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1)
• Cinobezile
• 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate
• 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazol(+-)-1h-imidazolbutanedioate(
• ritmalan
• ole(1:1)
• ro22-7796/001
• 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate, Cibenol, Cipralan, Exacor
• cibenzolinesuccinate(1:1)
• butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz
• butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazole(1:1)
• Cibenzoline succinate

Cibenzolinesuccinate

CAS: 100678-32-8

Formula: C₂₂H₂₄N₂O₄

Color and Shape: Solid

Molecular weight: 380.4370

Ref: IN-DA0002M3

Cibenzoline succinate

CAS: 100678-32-8

Formula: C₁₈H₁₈N₂·C₄H₆O₄

Molecular weight: 380.44

Ref: 7W-GP3248

CibenzolineSuccinate

Controlled Product

CAS: 100678-32-8

Applications Cibenzoline Succinate acts as a highly active class I antiarrhythmic agent.
References Xie, C. et al.: Handbook. Metab. Pathway. Xenobio., 3, 1110 (2014);

Formula: C₁₈H₁₈N₂·C₄H₆O₄

Color and Shape: Neat

Molecular weight: 380.44

Ref: TR-C535725