CymitQuimica logo

CAS 10068-65-2

:

Z-Thr(tBu)-OSu

Description:
Z-Thr(tBu)-OSu, also known as Z-Serine(t-butyl)-N-hydroxysuccinimide ester, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a Z (benzyloxycarbonyl) protecting group on the threonine amino acid, which helps to protect the amino group during chemical reactions. The t-butyl group enhances the hydrophobicity of the molecule, aiding in solubility and stability in organic solvents. The presence of the N-hydroxysuccinimide (OSu) moiety allows for efficient coupling reactions with amines, making it a valuable reagent in the formation of peptide bonds. This compound is typically utilized in the synthesis of peptides and proteins, particularly in the context of solid-phase peptide synthesis. Its stability under various conditions and compatibility with different coupling strategies make it a versatile tool in organic and medicinal chemistry. As with many chemical substances, proper handling and safety precautions should be observed due to potential reactivity and toxicity.
Formula:C20H26N2O7
InChI:InChI=1S/C20H26N2O7/c1-13(28-20(2,3)4)17(18(25)29-22-15(23)10-11-16(22)24)21-19(26)27-12-14-8-6-5-7-9-14/h5-9,13,17H,10-12H2,1-4H3,(H,21,26)/t13-,17+/m1/s1
InChI key:AKQWPEOOTKFCGI-DYVFJYSZSA-N
SMILES:C[C@H]([C@@H](C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2=CC=CC=C2)OC(C)(C)C
Synonyms:
  • Z-Thr(But)-OSu
Found 3 products.