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CAS 1007786-48-2

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  • JNK-IN-23

    CAS:
    JNK-IN-23 (Compound K12) is an inhibitor of JNK. It effectively inhibits the proliferation of MDA-MB-231 cells with a GIC50 of 30 nM. In vivo, JNK-IN-23 blocks metastatic growth of triple-negative breast cancer (TNBC). Additionally, it suppresses the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and the pyruvate dehydrogenase complex (PDHC).
    Formula:C19H18N4OS2
    Color and Shape:Solid
    Molecular weight:382.50

    Ref: TM-T210950

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