CAS 10078-25-8
:Perphenazine sulfoxide
Description:
Perphenazine sulfoxide is a chemical compound derived from perphenazine, which is an antipsychotic medication. It is characterized by the presence of a sulfoxide functional group, which introduces unique properties compared to its parent compound. The molecular structure typically includes a phenothiazine core, which is common in many antipsychotic drugs, and the sulfoxide group enhances its pharmacological profile. Perphenazine sulfoxide is known for its potential use in psychiatric treatment, exhibiting antipsychotic and antiemetic effects. It is generally a solid at room temperature and may have varying solubility in different solvents, which is influenced by the presence of the sulfoxide group. The compound's stability, reactivity, and biological activity can be affected by factors such as pH and temperature. As with many pharmaceuticals, safety and efficacy are critical, and its use should be guided by clinical evidence and regulatory standards. Overall, perphenazine sulfoxide represents an important compound in medicinal chemistry, particularly in the context of neuropharmacology.
Formula:C21H26ClN3O2S
InChI:InChI=1S/C21H26ClN3O2S/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)28(21)27)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
InChI key:InChIKey=WXJXTMQMAOYROI-UHFFFAOYSA-N
SMILES:C(CCN1CCN(CCO)CC1)N2C=3C(S(=O)C=4C2=CC=CC4)=CC=C(Cl)C3
Synonyms:- 1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, S-oxide
- 1-Piperazineethanol, 4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-
- 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, S-oxide
- 2-Chloro-10-(3-(4-(2-Hydroxyethyl)-7-Piperazinyl)Propyl)Phenothiazine
- 2-{4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
- 4-(3-(2-Chlorophenothiazin-10-Yl)Propyl)-1-Piperazineethanosulfoxide
- 4-[3-(2-Chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
- Ethaperazine sulfoxide
- Perphenazine sulfoxide
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Found 8 products.
Perphenazine Sulfoxide
CAS:Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fusedFormula:C21H26ClN3O2SColor and Shape:White Crystalline PowderMolecular weight:419.14343Perphenazine EP Impurity A
CAS:Formula:C21H26ClN3O2SColor and Shape:White To Off-White SolidMolecular weight:419.972-[4-[3-(2-Chloro-5-oxido-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol (Perphenazine Sulphoxide)
CAS:Controlled ProductFormula:C21H26ClN3O2SColor and Shape:NeatMolecular weight:419.97Perphenazine Sulfoxide
CAS:Controlled ProductImpurity Perphenazine EP Impurity A
Applications Perphenazine Sulfoxide (Perphenazine EP Impurity A) acts as a D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
References Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975), O Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),Formula:C21H26ClN3O2SColor and Shape:NeatMolecular weight:419.97







