CAS 100823-03-8

1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-

Description:

1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]- is a chemical compound characterized by its isoindole structure, which features a fused bicyclic system comprising a five-membered ring and a six-membered ring. The presence of the amino group at the 5-position and the bulky 2,6-bis(1-methylethyl)phenyl substituent contributes to its unique properties, including potential steric hindrance and enhanced lipophilicity. This compound may exhibit biological activity, making it of interest in medicinal chemistry and drug development. Its molecular structure suggests potential interactions with biological targets, which could lead to various pharmacological effects. The CAS number 100823-03-8 allows for precise identification and retrieval of information regarding this substance in chemical databases. As with many organic compounds, its solubility, stability, and reactivity can vary based on environmental conditions and the presence of other chemical species. Proper handling and safety measures should be observed when working with this compound in laboratory settings.

Formula: C₂₀H₂₂N₂O₂

InChI: InChI=1S/C20H22N2O2/c1-11(2)14-6-5-7-15(12(3)4)18(14)22-19(23)16-9-8-13(21)10-17(16)20(22)24/h5-12H,21H2,1-4H3

InChI key: NRPIRIUWEKTNGQ-UHFFFAOYSA-N

SMILES: CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C=C(C=C3)N

Synonyms:

• Cyclin dependent kinase,Apoptotic,Mitotic,Inhibitor,Immunomodulatory,Derivative,inhibit,CDK,TC-11,Bcl-2 Family,TC 11,Antitumor,TC11,Phenylphthalimide,Death,Caspase
• 1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-
• CLT-003
• 5-Amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione
• 1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
• TC11

TC11

CAS: 100823-03-8

TC11

Formula: C₂₀H₂₂N₂O₂

Purity: 97.5%

Molecular weight: 322.4

Ref: 54-BUP10952

5-Amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione

CAS: 100823-03-8

Formula: C₂₀H₂₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 322.4009

Ref: IN-DA0002YC

TC11

CAS: 100823-03-8

TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis

Formula: C₂₀H₂₂N₂O₂

Purity: 97.86%

Color and Shape: Yellow Solid

Molecular weight: 322.4009

Ref: TM-T9083

5-Amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione

CAS: 100823-03-8

5-Amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione

Formula: C₂₀H₂₂N₂O₂

Purity: 97%

Molecular weight: 322.4

Ref: IN-DG01393173

2-(2,6-Diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione

CAS: 100823-03-8

2-(2,6-Diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione is a cytostatic drug that induces apoptosis by inhibiting the activity of HDACs. It has been shown to inhibit the growth of subcutaneous tumors in mice and is currently being evaluated for its anticancer activity. This drug also has a pharmacokinetic study and pharmacokinetic properties that are different from other HDAC inhibitors. This drug may be used as an adjuvant therapy for cancer treatment or to prevent recurrence. The prognosis of patients taking 2-(2,6-Diisopropylphenyl)-5-amino-1H-isoindole-1,3-dione is better than those who are not taking it.

Formula: C₂₀H₂₂N₂O₂

Purity: Min. 95%

Molecular weight: 322.4 g/mol

Ref: 3D-AEA82303