CAS 100846-24-0: 5-(Trifluoromethyl)indole

Description: 5-(Trifluoromethyl)indole is an organic compound characterized by the presence of an indole ring substituted with a trifluoromethyl group at the 5-position. The indole structure consists of a fused benzene and pyrrole ring, contributing to its aromatic properties and potential biological activity. The trifluoromethyl group, which is a highly electronegative substituent, significantly influences the compound's chemical reactivity and lipophilicity, often enhancing its pharmacological properties. This compound is typically a solid at room temperature and is known for its stability under various conditions, although it may undergo reactions typical of indole derivatives, such as electrophilic substitution. Its unique structure makes it of interest in medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. Additionally, the presence of fluorine atoms can improve metabolic stability and bioavailability, making it a valuable scaffold in drug design. Safety and handling precautions should be observed due to the potential toxicity associated with fluorinated compounds.

Formula: C₈H₇BrFNO

InChI: InChI=1/C8H7BrFNO/c1-5(12)11-8-3-2-6(10)4-7(8)9/h2-4H,1H3,(H,11,12)

Synonyms:

• 1H-Indole, 5-(Triflu Oromethyl)- (9Ci)
• 5-Trifluoromethyl Indole ,98%
• N-(2-bromo-4-fluorophenyl)acetamide

5-(Trifluoromethyl)indole, 98%

CAS: 100846-24-0

In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of …

• Formula: C₉H₆F₃N
• Purity: 98%
• Color and Shape: Pale yellow to brown, Powder
• Molecular weight: 185.15

1H-Indole, 5-(trifluoromethyl)-

CAS: 100846-24-0

• Formula: C₉H₆F₃N
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 185.1458

5-(Trifluoromethyl)-1H-indole

CAS: 100846-24-0

• Formula: C₉H₆F₃N
• Purity: By gc: 99.2% (Typical Value in Batch COA)
• Color and Shape: yellow powder
• Molecular weight: 185.15g/mol

5-Trifluoromethylindole

CAS: 100846-24-0

• Formula: C₉H₆F₃N
• Molecular weight: 185.15

5-(Trifluoromethyl)indole

CAS: 100846-24-0

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 185.1490020751953

5-(Trifluoromethyl)indole

CAS: 100846-24-0

5-(Trifluoromethyl)indole is an indole derivative that binds to both orthosteric and allosteric sites of the …

• Formula: C₉H₆F₃N
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 185.15 g/mol

5-(Trifluoromethyl)indole

CAS: 100846-24-0

5-(Trifluoromethyl)indole is a useful scaffold, versatile building block, useful intermediate and reaction component. 5-(Trifluoromethyl)indole is …

• Formula: C₉H₆F₃N
• Purity: Min. 97.0 Area-%
• Molecular weight: 185.15 g/mol