CAS 100986-85-4

Levofloxacin

Description:

Levofloxacin is a synthetic fluoroquinolone antibiotic that is primarily used to treat a variety of bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for respiratory tract infections, urinary tract infections, and skin infections, among others. The chemical structure of levofloxacin includes a bicyclic core with a fluorine atom, which enhances its antibacterial potency. It is known for its ability to inhibit bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and repair. Levofloxacin is typically administered orally or intravenously and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics are favorable, with a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include gastrointestinal disturbances, central nervous system effects, and potential tendon damage. Due to its broad activity, levofloxacin is often reserved for specific infections to mitigate the risk of developing antibiotic resistance.

Formula: C₁₈H₂₀FN₃O₄

InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1

InChI key: InChIKey=GSDSWSVVBLHKDQ-JTQLQIEISA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@H](C)N3C=C1C(O)=O

Synonyms:

• (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• (S)-(-)-Ofloxacin
• (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-
• 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• Cravit
• Dr 3355
• Floxin
• Floxin Otic
• Hr 355
• Iquix
• Levaquin
• Levoflox
• Levofloxacin
• Levofloxacino
• Levofloxacinum
• Lexoflon
• Loxof
• Mp 376
• Ofloxacin Otic
• Ofloxacin S-(-)-form
• Ofloxacina
• Ofloxacine
• Ofloxacino
• Ofloxacinum
• Oflx
• Oftaquix
• Oxaldin
• Quinsair
• Quixin
• Rwj 25213-097
• Tavanic
• Unibiotic
• Venaxan
• (-)-Ofloxacin

Levofloxacin

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Purity: >98.0%(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 361.37

Ref: 3B-L0193

Levofloxacin, 98%

CAS: 100986-85-4

Levofloxacin, 98%; Broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance, and resistance prevention studies. Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell divis

Formula: C₃₆H₄₂F₂N₆O₉

Purity: 98%

Color and Shape: Powder, White to yellow

Molecular weight: 740.76

Ref: 02-J66943

Levofloxacin

CAS: 100986-85-4

Color and Shape: Neat

Ref: 61-FOR0846.00

Levofloxacin

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄·xH₂O

Purity: 98.0 - 102.0 % (anhydrous basis)

Color and Shape: White to light-yellow powder or crystals

Molecular weight: 361.37 (anhydrous)

Ref: 7W-GA6417

Levofloxacin

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Color and Shape: Pale Yellow Solid

Molecular weight: 361.37

Ref: 4Z-L-231

Levofloxacin

CAS: 100986-85-4

Levofloxacin

Purity: ≥95%

Molecular weight: 361.37g/mol

Ref: 54-BUP16616

Levofloxacin

CAS: 100986-85-4

Levofloxacin

Formula: C₁₈H₂₀FN₃O₄

Purity: By hplc: 99.74% (Typical Value in Batch COA)

Color and Shape: white to yellow solid

Molecular weight: 361.3675g/mol

Ref: 54-BIL1009

Levofloxacin

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Color and Shape: Neat

Molecular weight: 361.37

Ref: 04-C14629730

LC PestiMix 5 10 µg/mL in Acetonitrile

CAS: 100986-85-4, 101-27-9, 1014-69-3, 104030-54-8, 106700-29-2, 112143-82-5, 1134-23-2, 115-26-4, 117718-60-2, 127-79-7, 131341-86-1, 14086-35-2, 1491-41-4, 15310-01-7, 153197-14-9, 1593-77-7, 1596-84-5, 183675-82-3, 18854-01-8, 1918-11-2, 1929-77-7, 210880-92-5, 219714-96-2, 22936-86-3, 2307-68-8, 23564-06-9, 25366-23-8, 2588-03-6, 2588-04-7, 2588-05-8, 2588-06-9, 26087-47-8, 2686-99-9, 299-86-5, 30043-49-3, 31120-85-1, 314-40-9, 3244-90-4, 3813-05-6, 3983-45-7, 470-90-6, 4726-14-1, 51218-45-2, 535-89-7, 53780-34-0, 59756-60-4, 61676-87-7, 62850-32-2, 64249-01-0, 644-64-4, 6552-12-1, 6552-13-2, 67018-59-1, 672-99-1, 673-04-1, 70217-36-6, 70630-17-0, 741-58-2, 759-94-4, 7700-17-6, 78-30-8, 79540-50-4, 80214-83-1, 81335-37-7, 83657-22-1, 85785-20-2, 86763-47-5, 88283-41-4, 89784-60-1, 947-02-4, 95-06-7, 96491-05-3, 99485-76-4, 99675-03-3

Color and Shape: Mixture

Ref: 04-A50000805AL

Levofloxacin

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 361.373

Ref: 10-F387019

Levofloxacin

Controlled Product

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Color and Shape: Neat

Molecular weight: 361.37

Ref: 86-MM0846.00

Levofloxacin

CAS: 100986-85-4

Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.

Formula: C₁₈H₂₀FN₃O₄

Purity: 98.14% - 99.80%

Color and Shape: Off-White To Yellow Crystals

Molecular weight: 361.37

Ref: TM-T6567

Levofloxacin-d3

Controlled Product

CAS: 100986-85-4

Applications Levofloxacin-d3, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.
References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),

Formula: C₁₈H₁₇D₃FN₃O₄

Color and Shape: Neat

Molecular weight: 364.39

Ref: TR-L360004

Levofloxacin

CAS: 100986-85-4

Applications Levofloxacin is an antibiotic compound.
References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992); North, D.S., et al.: Pharmacotherapy, 18, 915 (1998); Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003);

Formula: C₁₈H₂₀FN₃O₄

Color and Shape: White To Off-White

Molecular weight: 361.37

Ref: TR-L360255

Levofloxacin (LVX), 98%

CAS: 100986-85-4, 138199-71-0

Formula: C₁₈H₂₀FN₃O₄

Purity: min. 98%

Color and Shape: Off - White to pale yellow, Crystalline powder

Molecular weight: 361.37

Ref: SR-23467

Levofloxacin

CAS: 100986-85-4

Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.

Formula: C₁₈H₂₀FN₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 361.37 g/mol

Ref: 3D-AL10796

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-

CAS: 100986-85-4

Formula: C₁₈H₂₀FN₃O₄

Color and Shape: Solid

Molecular weight: 361.3675

Ref: IN-DA0003DQ