CAS 101-93-9

Phenacaine

Description:

Phenacaine, with the CAS number 101-93-9, is a chemical compound classified as a local anesthetic. It is an aromatic amine and is structurally related to other local anesthetics, exhibiting properties that allow it to block nerve conduction. Phenacaine is typically used in medical applications for its analgesic effects, particularly in ophthalmology for eye procedures. The compound is characterized by its relatively low solubility in water, which can influence its formulation in pharmaceutical preparations. It has a moderate to high melting point, indicating its solid state at room temperature. Phenacaine's mechanism of action involves the inhibition of sodium ion influx through voltage-gated sodium channels, which prevents the propagation of nerve impulses. While it has been effective in clinical settings, its use has declined in favor of newer anesthetics with improved safety profiles and efficacy. As with many local anesthetics, potential side effects may include allergic reactions or systemic toxicity if used improperly. Overall, phenacaine remains a significant compound in the study of anesthetic agents.

Formula: C₁₈H₂₂N₂O₂

InChI: InChI=1S/C18H22N2O2/c1-4-21-17-10-6-15(7-11-17)19-14(3)20-16-8-12-18(13-9-16)22-5-2/h6-13H,4-5H2,1-3H3,(H,19,20)

InChI key: InChIKey=QXDAEKSDNVPFJG-UHFFFAOYSA-N

SMILES: N(=C(NC1=CC=C(OCC)C=C1)C)C2=CC=C(OCC)C=C2

Synonyms:

• Phenacaine
• N,N′-Bis(4-ethoxyphenyl)ethanimidamide
• N,N-bis(4-ethoxyphenyl)acetamidine
• Acetamidine, N,N′-bis(p-ethoxyphenyl)-
• (1E)-N,N'-bis(4-ethoxyphenyl)ethanimidamide
• Ethanimidamide, N,N′-bis(4-ethoxyphenyl)-
• N,N′-Bis(p-ethoxyphenyl)acetamidine

Phenacaine

CAS: 101-93-9

Phenacaine, also known as Holocaine, is a local anesthetic that blocks certain Ca 2+ enzymes in red blood cells, brain, and heart.

Formula: C₁₈H₂₂N₂O₂

Color and Shape: Solid

Molecular weight: 298.38

Ref: TM-T75315