CAS 101-93-9
:Phenacaine
Description:
Phenacaine, with the CAS number 101-93-9, is a chemical compound classified as a local anesthetic. It is an aromatic amine and is structurally related to other local anesthetics, exhibiting properties that allow it to block nerve conduction. Phenacaine is typically used in medical applications for its analgesic effects, particularly in ophthalmology for eye procedures. The compound is characterized by its relatively low solubility in water, which can influence its formulation in pharmaceutical preparations. It has a moderate to high melting point, indicating its solid state at room temperature. Phenacaine's mechanism of action involves the inhibition of sodium ion influx through voltage-gated sodium channels, which prevents the propagation of nerve impulses. While it has been effective in clinical settings, its use has declined in favor of newer anesthetics with improved safety profiles and efficacy. As with many local anesthetics, potential side effects may include allergic reactions or systemic toxicity if used improperly. Overall, phenacaine remains a significant compound in the study of anesthetic agents.
Formula:C18H22N2O2
InChI:InChI=1S/C18H22N2O2/c1-4-21-17-10-6-15(7-11-17)19-14(3)20-16-8-12-18(13-9-16)22-5-2/h6-13H,4-5H2,1-3H3,(H,19,20)
InChI key:InChIKey=QXDAEKSDNVPFJG-UHFFFAOYSA-N
SMILES:N(=C(NC1=CC=C(OCC)C=C1)C)C2=CC=C(OCC)C=C2
Synonyms:- Phenacaine
- N,N′-Bis(4-ethoxyphenyl)ethanimidamide
- N,N-bis(4-ethoxyphenyl)acetamidine
- Acetamidine, N,N′-bis(p-ethoxyphenyl)-
- (1E)-N,N'-bis(4-ethoxyphenyl)ethanimidamide
- Ethanimidamide, N,N′-bis(4-ethoxyphenyl)-
- N,N′-Bis(p-ethoxyphenyl)acetamidine
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Phenacaine
CAS:Phenacaine (Holocaine) is a local anesthetic that inhibits calmodulin-dependent Ca²⁺-ATPase and cyclic nucleotide phosphodiesterases in brain and heart.Formula:C18H22N2O2Purity:99.98%Color and Shape:SolidMolecular weight:298.38



