CAS 101214-22-6
:Fmoc-Glu(OtBu)-OSu
Description:
Fmoc-Glu(OtBu)-OSu, also known as Fmoc-Glutamic acid (OtBu) derivative with an N-hydroxysuccinimide (OSu) moiety, is a chemical compound commonly used in peptide synthesis and bioconjugation. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino acid, allowing for selective deprotection during peptide assembly. The glutamic acid component provides a carboxylic acid functionality, which can participate in various coupling reactions. The tert-butyl (OtBu) group is a protecting group for the side-chain carboxyl group of glutamic acid, enhancing the stability and solubility of the compound. The OSu group facilitates the formation of stable amide bonds with primary amines, making it useful for conjugating peptides to other biomolecules. This compound is typically utilized in solid-phase peptide synthesis and in the development of peptide-based therapeutics. Its stability under standard laboratory conditions and compatibility with various coupling reagents make it a valuable tool in organic and medicinal chemistry.
Formula:C28H30N2O6
InChI:InChI=1S/C28H30N2O8/c1-28(2,3)37-25(33)15-12-22(26(34)38-30-23(31)13-14-24(30)32)29-27(35)36-16-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21/h4-11,21-22H,12-16H2,1-3H3,(H,29,35)/t22-/m0/s1
InChI key:TUXJIYSGLYYEHH-QFIPXVFZSA-N
SMILES:CC(C)(C)OC(=O)CC[C@@H](C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Synonyms:- Fmoc-Glu(OBut)-OSu
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(S)-5-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioate
CAS:(S)-5-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioateFormula:C28H30N2O8Purity:98%Molecular weight:522.55(S)-5-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioate
CAS:(S)-5-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioateFormula:C28H30N2O8Purity:98%Molecular weight:522.55Fmoc-Glu(OtBu)-OSu
CAS:Fmoc-Glu(OtBu)-OSu is employed in synthesizing N3S chelating agents and bifunctional and trifunctional carboxy-terminated polyethylene glycolation reagents.Formula:C28H30N2O8Molecular weight:522.55
