CAS 10125-07-2

Cyclo(-Gly-Phe)

Description:

Cyclo(-Gly-Phe), also known as cyclo(Gly-Phe), is a cyclic dipeptide composed of glycine (Gly) and phenylalanine (Phe) residues. This compound features a unique cyclic structure that can influence its biological activity and stability compared to its linear counterparts. Cyclo(-Gly-Phe) exhibits characteristics typical of peptides, including the potential for specific interactions with biological receptors, which may contribute to its pharmacological properties. The cyclic nature of the molecule can enhance its resistance to enzymatic degradation, making it a subject of interest in drug design and development. Additionally, the presence of the aromatic phenylalanine side chain may impart unique hydrophobic interactions, influencing solubility and binding affinity in biological systems. Cyclo(-Gly-Phe) may also exhibit various conformational states, which can affect its reactivity and interaction with other biomolecules. Overall, this compound represents a fascinating area of study within peptide chemistry, with implications for medicinal chemistry and biochemistry.

Formula: C₁₁H₁₂N₂O₂

InChI: InChI=1S/C11H12N2O2/c14-10-7-12-11(15)9(13-10)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,15)(H,13,14)/t9-/m0/s1

InChI key: UZOJHXFWJFSFAI-VIFPVBQESA-N

SMILES: C1C(=O)N[C@H](C(=O)N1)CC2=CC=CC=C2

Cyclo(-Gly-Phe)

CAS: 10125-07-2

Bachem ID: 4028308.

Formula: C₁₁H₁₂N₂O₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 204.23

Ref: 01-4028308

2,5-Piperazinedione, 3-(phenylmethyl)-, (3S)-

CAS: 10125-07-2

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.2252

Ref: IN-DA000426

(S)-3-Benzylpiperazine-2,5-dione

CAS: 10125-07-2

(S)-3-Benzylpiperazine-2,5-dione

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Molecular weight: 204.23

Ref: 54-OR1063908

(S)-3-Benzylpiperazine-2,5-dione

CAS: 10125-07-2

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Molecular weight: 204.23

Ref: IN-DG122560

(S)-3-Benzylpiperazine-2,5-dione

CAS: 10125-07-2

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.229

Ref: 10-F463130

Cyclo(-Gly-Phe)

Controlled Product

CAS: 10125-07-2

Applications Cyclo(-Gly-Phe) is used to study the thermodynamics of protein unfolding. It is also able to cause gelation in a wide variety of organic fluids, including edible oils, glyceryl esters, alcohols, and aromatic molecules.
References Murphy, K., et al.: J. Mol. Biol., 222, 699 (1991); Hanabusa, K., et al.: J. Colloid Interface Sci., 224, 231 (2000)

Formula: C₁₁H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 204.23

Ref: TR-C989715

Cyclo(-Gly-L-Phe)

CAS: 10125-07-2

Cyclo(-Gly-L-Phe) is a cyclic peptide with hydroxyl group at the C-terminal. It has been shown to have high uptake and cytotoxicity in intestinal cells. The uptake of Cyclo(-Gly-L-Phe) was found to be reversed phase high performance liquid chromatography (RP-HPLC). Cyclo(-Gly-L-Phe) is also cytotoxic to coryneform, caco2, and HeLa cells and inhibits cellular protein synthesis through inhibition of ribosome function.

Formula: C₁₁H₁₂N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 204.23 g/mol

Ref: 3D-FC49429