Description:2-Methoxybenzenesulfonyl chloride, also known as anisole sulfonyl chloride, is an aromatic sulfonyl chloride characterized by the presence of a methoxy group (-OCH₃) attached to a benzene ring, which is further substituted with a sulfonyl chloride group (-SO₂Cl). This compound typically appears as a colorless to pale yellow liquid and is known for its strong reactivity due to the sulfonyl chloride functional group, making it a useful intermediate in organic synthesis. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. The compound is sensitive to moisture and can hydrolyze to form the corresponding sulfonic acid. 2-Methoxybenzenesulfonyl chloride is often employed in the synthesis of sulfonamides, as well as in the preparation of various pharmaceuticals and agrochemicals. Due to its reactivity, it should be handled with care, using appropriate safety measures to avoid exposure, as it can be corrosive and irritating to the skin and respiratory system.
For synthesis and pharmacological evaluation of sulfonamide derivatives of thiazolidin-4-ones 5-Bromo-2-methoxybenzenesulfonyl chloride is used. This …
Formula:
C7H7ClO3S
Purity:
95%
Color and Shape:
Crystals or powder or crystalline powder, White to pale cream
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