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CAS 101342-45-4

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4-Epichlortetracycline hydrochloride 'canbe used as secondary standard'

Description:
4-Epichlortetracycline hydrochloride, with the CAS number 101342-45-4, is a semi-synthetic derivative of tetracycline, a class of broad-spectrum antibiotics. This compound exhibits characteristics typical of tetracyclines, including a complex polycyclic structure that contributes to its antibacterial activity. It is known for its ability to inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit, making it effective against a variety of gram-positive and gram-negative organisms. As a hydrochloride salt, it is typically more soluble in water, facilitating its use in various formulations. The substance is often utilized as a secondary standard in analytical chemistry due to its stability and well-defined properties, allowing for accurate calibration in assays. Its application extends beyond pharmaceuticals, as it can also serve in research settings to study antibiotic resistance and microbial interactions. However, like other tetracyclines, it may have side effects and contraindications, necessitating careful handling and usage in accordance with safety guidelines.
Formula:C22H24Cl2N2O8
InChI:InChI=1/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8?,15-,21+,22?;/m1./s1
Synonyms:
  • Ectc
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