CAS 1013920-15-4
:Formula:C23H26FN5O3
InChI:InChI=1S/C23H26FN5O3/c1-12-19(10-17-16-9-14(24)5-6-18(16)27-21(17)30)25-13(2)20(12)22(31)26-15-7-8-29(11-15)23(32)28(3)4/h5-6,9-10,15,25H,7-8,11H2,1-4H3,(H,26,31)(H,27,30)/b17-10-/t15-/m0/s1
InChI key:KMIOJWCYOHBUJS-HAKPAVFJSA-N
SMILES:CC1=C(NC(=C1C(=O)N[C@H]2CCN(C2)C(=O)N(C)C)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O
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(S,Z)-N-(1-(Dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS:(S,Z)-N-(1-(Dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamideFormula:C23H26FN5O3Purity:99%Molecular weight:439.48Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48X-82 (Vorolanib)
CAS:Vorolanib is a small molecule that binds to the death receptor 4 (DR4) and inhibits angiogenesis. Vorolanib is a member of the everolimus group. This drug has been shown to inhibit tumor growth in a mouse model of metastatic cancer by blocking the activation of DR4, which signals cells to grow, and by inhibiting the production of pro-angiogenic factors. Vorolanib has also been shown to have anti-inflammatory properties. Vorolanib binds to the death receptor 4 (DR4) and inhibits angiogenesis by blocking activation of this protein, which signals cells to grow, and by inhibiting the production of pro-angiogenic factors. Vorolanib also has anti-inflammatory properties due to its ability to suppress myeloid derived suppressor cells (MDSCs).
Formula:C23H26FN5O3Purity:Min. 95%Molecular weight:439.4 g/mol
