CAS 101530-10-3
:Lanoconazole
Description:
Lanoconazole is an antifungal agent primarily used in the treatment of superficial fungal infections. It belongs to the class of imidazole derivatives and exhibits broad-spectrum antifungal activity against various dermatophytes and yeast. The chemical structure of lanoconazole features a triazole ring, which is crucial for its mechanism of action, as it inhibits the enzyme lanosterol 14α-demethylase, disrupting ergosterol synthesis in fungal cell membranes. This disruption leads to increased membrane permeability and ultimately cell death. Lanoconazole is typically administered topically, making it effective for localized infections with minimal systemic absorption. Its pharmacokinetic profile indicates a relatively low toxicity, which contributes to its safety in clinical use. Additionally, lanoconazole has shown efficacy in treating conditions such as tinea, candidiasis, and other dermatological fungal infections. Its formulation may include creams, lotions, or solutions, allowing for versatile application depending on the infection site. Overall, lanoconazole is a valuable agent in the antifungal therapeutic arsenal, particularly for dermatological applications.
Formula:C14H10ClN3S2
InChI:InChI=1/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/b14-12+
InChI key:InChIKey=ZRTQSJFIDWNVJW-WYMLVPIENA-N
SMILES:C(\C#N)(=C/1\SC(CS1)C2=C(Cl)C=CC=C2)/N3C=CN=C3
Synonyms:- (2Z)-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)ethanenitrile
- (αE)-α-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
- 1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-
- 1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-
- 2E)-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)ethanenitrile
- Astat
- Latoconazole
- Nnd 318
- Tjn 318
- Lanoconazole
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-
CAS:Formula:C14H10ClN3S2Purity:98.00%Color and Shape:SolidMolecular weight:319.8323Lanoconazole
CAS:Lanoconazole is an antifungal imidazole that is potent and orally available and acts by inhibiting the synthesis of ergosterol in fungal cell membranes.Formula:C14H10ClN3S2Purity:98% - 99.97%Color and Shape:Yellow SolidMolecular weight:319.83Lanoconazole
CAS:Anti-fungal; sterol demethylase inhibitorFormula:C14H10ClN3S2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:319.83 g/molLanoconazole
CAS:Controlled ProductApplications Antifungal.
References Oka, H., et al.: Arzneim.-Forsch., 42, 345 (1992), Niwano, Y., et al.: Antimicrob. Agents Chemother., 38, 2204 (1994), Munt, L.: et al.: Oyo Yakuri, 43, 195 (1992),Formula:C14H10ClN3S2Color and Shape:NeatMolecular weight:319.83
![1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0004QG.jpg&w=3840&q=75)
