CAS 101555-62-8

fmoc-D-proline

Description:

Fmoc-D-proline is a derivative of the amino acid proline, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group while allowing for the selective coupling of other amino acids. Fmoc-D-proline retains the unique cyclic structure of proline, which contributes to its conformational rigidity and influences the secondary structure of peptides. The Fmoc group can be easily removed under basic conditions, facilitating the subsequent steps in peptide synthesis. Fmoc-D-proline is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its use in research and pharmaceutical applications is significant, particularly in the development of peptide-based drugs and in studying protein folding and function.

Formula: C₂₀H₁₉NO₄

InChI: InChI=1/C20H19NO4.H2O/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17;/h1-4,6-9,17-18H,5,10-12H2,(H,22,23);1H2/t18-;/m1./s1

InChI key: InChIKey=ZPGDWQNBZYOZTI-GOSISDBHSA-N

SMILES: C(OC(=O)N1[C@@H](C(O)=O)CCC1)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• (2R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
• (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
• (2R)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid
• (R)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid
• (R)-N-(9-Fluorenylmethoxycarbonyl)proline
• (R)-N-FMOC-proline
• 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (2R)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (R)-
• 1-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-proline
• 1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]-<span class="text-smallcaps">D</span>-proline
• 300: PN: US20070042401 PAGE: 38 claimed protein
• 992: PN: WO2006135786 PAGE: 71 claimed protein
• Fmoc-D-Pro-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">D</span>-proline
• N-alpha-(9-fluorenylmethyloxycarbonyl)-D-proline
• N-(9-Fluorenylmethoxycarbonyl)-D-proline
• N-ALPHA-FMOC-D-PROLINE
• FMOC-D-PRO
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-PROLINE MONOHYDRATE
• FMOC-D-PROLINE extrapure
• FMOC-D-PRO-OH H2O
• n-fmoc-d-proline
• (R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID
• FMOC-D-PROLINE
• (R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-(9H-FLUOREN-9-YLMETHYL) ESTER
• FMOC-D-
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-PROLINE
• 9-FLUORENYLMETHOXYCARBONYL-D-PROLINE
• 1-(9H-FLUOREN-9-YLMETHYL) ESTER
• N-(9-FLUORENYLMETHOXYCARBONYL)-D-PYRROLIDINE-2-CARBOXYLIC ACID
• n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-proline
• FMOC-D-PYRD(2)-OH

Fmoc-D-Pro-OH

CAS: 101555-62-8

Bachem ID: 4011894.

Formula: C₂₀H₁₉NO₄

Purity: 99.9%

Color and Shape: White

Molecular weight: 337.38

Ref: 01-4011894

1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (2R)-

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 337.3692

Ref: IN-DA0004RL

Fmoc-D-Pro-OH

CAS: 101555-62-8

Fmoc-D-Pro-OH

Formula: C₂₀H₁₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 337.37

Ref: 54-OR1013352

D-Proline-2,5,5-d3-N-FMOC

CAS: 101555-62-8

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 340.39

Ref: 3U-D7177

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 337.38

Ref: 3B-F0606

Fmoc-D-Pro-OH

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Purity: ≥ 99.0%

Color and Shape: White or almost white powder

Molecular weight: 337.38

Ref: 7W-GM1101

Fmoc-D-Pro-OH

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Molecular weight: 337.38

Ref: 4Z-P-166010

Fmoc-D-Pro-OH

CAS: 101555-62-8

Fmoc-D-Pro-OH is a building block for peptide synthesis. It is a protected form of proline with an amido group, which can be used to synthesize polypeptides. Fmoc-D-Pro-OH can be coupled with other amino acids using the aldol condensation or methodologies like the strategy of organocatalysts. This building block is also useful in the synthesis of macrocycles and cyclohexanones, which are aliphatic and cyclic compounds. The recoverable nature of Fmoc-D-Pro-OH allows it to be reused in multiple reactions, so it is an economical choice for Building Blocks.

Formula: C₂₀H₁₉NO₄

Purity: Min. 95%

Molecular weight: 337.38 g/mol

Ref: 3D-FDP-1826-PI

Fmoc-D-Pro-OH

CAS: 101555-62-8

M03373 - Fmoc-D-Pro-OH

Formula: C₂₀H₁₉NO₄

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 337.375

Ref: 10-M03373

Fmoc-D-Pro-OH

CAS: 101555-62-8

Fmoc-D-Pro-OH

Formula: C₂₀H₁₉NO₄

Purity: 98%

Molecular weight: 337.37

Ref: IN-DG1191

FMOC-D-Proline extrapure, 99%

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 337.38

Ref: SR-53412

D-Proline-2,5,5-d3-N-FMOC

Controlled Product

CAS: 101555-62-8

Formula: C₂₀D₃H₁₆NO₄

Color and Shape: Neat

Molecular weight: 340.39

Ref: TR-P756016

D-Proline-N-Fmoc

CAS: 101555-62-8

Formula: C₂₀H₁₉NO₄

Molecular weight: 337.4

Ref: ST-EA-CP-L28012

Fmoc-D-proline

CAS: 101555-62-8

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Formula: C₂₀H₁₉NO₄

Purity: Min. 95%

Molecular weight: 337.37 g/mol

Ref: 3D-FF48062