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CAS 1015787-98-0

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Gefapixant

Description:
Gefapixant, identified by its CAS number 1015787-98-0, is a novel chemical compound primarily developed for therapeutic use in treating chronic cough. It functions as a selective P2X3 receptor antagonist, which plays a crucial role in the sensory pathways associated with cough reflex. This mechanism of action helps to reduce the hypersensitivity of the cough reflex, making it a potential treatment option for patients suffering from chronic cough conditions. Gefapixant is characterized by its relatively low molecular weight and specific structural features that enable its interaction with the P2X3 receptor. The compound has undergone various clinical trials to assess its efficacy and safety profile, showing promise in alleviating cough symptoms without the sedative effects commonly associated with other cough suppressants. As with many pharmacological agents, its development has included extensive studies on pharmacokinetics, metabolism, and potential side effects to ensure its therapeutic viability. Overall, gefapixant represents a targeted approach to managing chronic cough, highlighting the importance of receptor-specific therapies in modern medicine.
Formula:C14H19N5O4S
InChI:InChI=1S/C14H19N5O4S/c1-7(2)8-4-10(22-3)12(24(17,20)21)5-9(8)23-11-6-18-14(16)19-13(11)15/h4-7H,1-3H3,(H2,17,20,21)(H4,15,16,18,19)
InChI key:HLWURFKMDLAKOD-UHFFFAOYSA-N
SMILES:CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)S(=O)(=O)N)OC
Found 9 products.